Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   F1612_RS03970 Genome accession   NZ_CP043843
Coordinates   805502..806218 (-) Length   238 a.a.
NCBI ID   WP_000688498.1    Uniprot ID   Q2VG52
Organism   Staphylococcus aureus strain NCCP 16830     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 800502..811218
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  F1612_RS03950 (F1612_04035) - 801594..802544 (+) 951 WP_000790329.1 LacI family DNA-binding transcriptional regulator -
  F1612_RS03955 (F1612_04040) - 802693..804177 (+) 1485 WP_000141427.1 sucrose-6-phosphate hydrolase -
  F1612_RS03960 (F1612_04045) - 804174..805133 (+) 960 WP_158172954.1 carbohydrate kinase family protein -
  F1612_RS03965 (F1612_04050) - 805321..805430 (-) 110 Protein_773 hypothetical protein -
  F1612_RS03970 (F1612_04055) agrA 805502..806218 (-) 717 WP_000688498.1 quorum-sensing response regulator AgrA Regulator
  F1612_RS03975 (F1612_04060) agrC 806237..807529 (-) 1293 WP_001657119.1 quorum-sensing sensor histidine kinase AgrC -
  F1612_RS03980 (F1612_04065) agrD 807554..807694 (-) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  F1612_RS03985 (F1612_04070) agrB 807691..808260 (-) 570 WP_001105707.1 accessory gene regulator AgrB -
  F1612_RS14105 hld 808550..808630 (+) 81 WP_000046022.1 delta-hemolysin -
  F1612_RS03995 (F1612_04080) - 809229..810014 (-) 786 WP_000867939.1 carbon-nitrogen family hydrolase -
  F1612_RS04000 (F1612_04085) - 810375..811001 (-) 627 WP_000522384.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27933.91 Da        Isoelectric Point: 6.0927

>NTDB_id=386152 F1612_RS03970 WP_000688498.1 805502..806218(-) (agrA) [Staphylococcus aureus strain NCCP 16830]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSRDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=386152 F1612_RS03970 WP_000688498.1 805502..806218(-) (agrA) [Staphylococcus aureus strain NCCP 16830]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAGAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCGCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q2VG52

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996

Multiple sequence alignment