Detailed information NTG0385877

Bioinformatically predicted

Overview

• Name: comGF
• Type: Machinery gene
• Locus tag: HHM65_RS00805
• Genome accession: NZ_CP051624
• Coordinates: 129942..130382 (+)
• Length: 146 a.a.
• NCBI ID: WP_170078125.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain TPCH-A74
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 124942..135382

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HHM65_RS00775 (HHM65_00780)	-	126623..126988 (+)	366	WP_003055257.1	DUF1033 family protein	-
HHM65_RS00780 (HHM65_00785)	comGA/cglA	127069..128010 (+)	942	WP_170078124.1	competence type IV pilus ATPase ComGA	Machinery gene
HHM65_RS00785 (HHM65_00790)	comGB	127946..128977 (+)	1032	WP_015057201.1	competence type IV pilus assembly protein ComGB	Machinery gene
HHM65_RS00790 (HHM65_00795)	comGC	128979..129305 (+)	327	WP_003055259.1	competence type IV pilus major pilin ComGC	Machinery gene
HHM65_RS00795 (HHM65_00800)	comGD	129280..129708 (+)	429	WP_041781473.1	competence type IV pilus minor pilin ComGD	Machinery gene
HHM65_RS00800 (HHM65_00805)	comGE	129716..129961 (+)	246	WP_003058569.1	competence type IV pilus minor pilin ComGE	Machinery gene
HHM65_RS00805 (HHM65_00810)	comGF	129942..130382 (+)	441	WP_170078125.1	competence type IV pilus minor pilin ComGF	Machinery gene
HHM65_RS00810 (HHM65_00815)	comGG	130405..130734 (+)	330	WP_003058539.1	competence type IV pilus minor pilin ComGG	-
HHM65_RS00815 (HHM65_00820)	comGH	130797..131750 (+)	954	WP_003060701.1	class I SAM-dependent methyltransferase	Machinery gene
HHM65_RS00820 (HHM65_00825)	-	131809..133005 (+)	1197	WP_015057203.1	acetate kinase	-
HHM65_RS00825 (HHM65_00830)	-	133311..133517 (+)	207	WP_003058508.1	helix-turn-helix transcriptional regulator	-
HHM65_RS00830 (HHM65_00835)	-	133620..134300 (+)	681	WP_012766451.1	type II CAAX endopeptidase family protein	-
HHM65_RS00835 (HHM65_00840)	-	134318..134755 (+)	438	WP_012766452.1	hypothetical protein	-

Sequence

Protein

• Length: 146 a.a.
• Molecular weight: 16938.59 Da
• Isoelectric Point: 10.7829

>NTDB_id=385877 HHM65_RS00805 WP_170078125.1 129942..130382(+) (comGF) [Streptococcus dysgalactiae subsp. equisimilis strain TPCH-A74]
MKKRTGRVQAFTFLEALIALLVISGSLLVYQGLTKTLLSHSRYLTKNDQDHWLLFSQQLREELGGARFHKVENNKLYIEK
GKKKLVLGQFKSHDFRKSAGNGQGYQPMLFGLSHSHIQAEQSRIRITLHWKSGLKRTFYYAFQDQP

Nucleotide

• Length: 441 bp

>NTDB_id=385877 HHM65_RS00805 WP_170078125.1 129942..130382(+) (comGF) [Streptococcus dysgalactiae subsp. equisimilis strain TPCH-A74]
TTGAAAAAAAGGACAGGTAGGGTCCAAGCATTTACTTTTTTAGAGGCTTTAATTGCCTTACTGGTGATATCAGGTTCTCT
TCTAGTGTATCAAGGATTGACCAAAACACTCCTTAGCCACAGTCGCTACCTTACCAAAAATGATCAAGACCATTGGCTTT
TGTTCTCCCAGCAGTTACGAGAAGAGTTAGGTGGAGCGCGATTTCACAAAGTAGAGAACAATAAATTATATATCGAAAAA
GGCAAGAAAAAACTAGTTTTAGGACAATTTAAAAGCCATGACTTTCGAAAATCGGCAGGCAATGGACAAGGTTATCAACC
CATGCTGTTTGGCCTGTCTCATAGTCATATACAAGCAGAGCAGTCTCGTATTCGTATTACCCTTCACTGGAAAAGTGGAC
TAAAAAGGACCTTCTACTATGCGTTTCAAGACCAACCTTAA

Domains

Predicted by InterProScan.

• Putative Competence protein ComGF (ComGF) (40-135)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF	Streptococcus mutans UA159	48.201	95.205	0.459
comGF	Streptococcus mutans UA140	47.482	95.205	0.452
comGF	Lactococcus lactis subsp. cremoris KW2	44.928	94.521	0.425
comGF/cglF	Streptococcus pneumoniae D39	43.066	93.836	0.404
comGF/cglF	Streptococcus mitis NCTC 12261	43.066	93.836	0.404
comGF/cglF	Streptococcus pneumoniae TIGR4	43.066	93.836	0.404
comGF/cglF	Streptococcus pneumoniae R6	43.066	93.836	0.404
comGF/cglF	Streptococcus mitis SK321	43.066	93.836	0.404
comGF/cglF	Streptococcus pneumoniae Rx1	43.066	93.836	0.404