Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGD   Type   Machinery gene
Locus tag   HHM65_RS00795 Genome accession   NZ_CP051624
Coordinates   129280..129708 (+) Length   142 a.a.
NCBI ID   WP_041781473.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae subsp. equisimilis strain TPCH-A74     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 124280..134708
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HHM65_RS00775 (HHM65_00780) - 126623..126988 (+) 366 WP_003055257.1 DUF1033 family protein -
  HHM65_RS00780 (HHM65_00785) comGA/cglA 127069..128010 (+) 942 WP_170078124.1 competence type IV pilus ATPase ComGA Machinery gene
  HHM65_RS00785 (HHM65_00790) comGB 127946..128977 (+) 1032 WP_015057201.1 competence type IV pilus assembly protein ComGB Machinery gene
  HHM65_RS00790 (HHM65_00795) comGC 128979..129305 (+) 327 WP_003055259.1 competence type IV pilus major pilin ComGC Machinery gene
  HHM65_RS00795 (HHM65_00800) comGD 129280..129708 (+) 429 WP_041781473.1 competence type IV pilus minor pilin ComGD Machinery gene
  HHM65_RS00800 (HHM65_00805) comGE 129716..129961 (+) 246 WP_003058569.1 competence type IV pilus minor pilin ComGE Machinery gene
  HHM65_RS00805 (HHM65_00810) comGF 129942..130382 (+) 441 WP_170078125.1 competence type IV pilus minor pilin ComGF Machinery gene
  HHM65_RS00810 (HHM65_00815) comGG 130405..130734 (+) 330 WP_003058539.1 competence type IV pilus minor pilin ComGG -
  HHM65_RS00815 (HHM65_00820) comGH 130797..131750 (+) 954 WP_003060701.1 class I SAM-dependent methyltransferase Machinery gene
  HHM65_RS00820 (HHM65_00825) - 131809..133005 (+) 1197 WP_015057203.1 acetate kinase -
  HHM65_RS00825 (HHM65_00830) - 133311..133517 (+) 207 WP_003058508.1 helix-turn-helix transcriptional regulator -
  HHM65_RS00830 (HHM65_00835) - 133620..134300 (+) 681 WP_012766451.1 type II CAAX endopeptidase family protein -

Sequence

Protein


Download         Length: 142 a.a.        Molecular weight: 16400.87 Da        Isoelectric Point: 9.9660

>NTDB_id=385875 HHM65_RS00795 WP_041781473.1 129280..129708(+) (comGD) [Streptococcus dysgalactiae subsp. equisimilis strain TPCH-A74]
MRLKNCNLKAFTMLESLLTLSVTSFIVLGLSVPVTSSYRRAQEQLFFTRFEHFYRHQQKLAILEHDQRVLTISSKQMLAA
EESLTIPDLIRVKNSQQLVIDQMGGNHSLAKIIFETTDQRVTYQFYLGSGNYQKTSQSLHRS

Nucleotide


Download         Length: 429 bp        

>NTDB_id=385875 HHM65_RS00795 WP_041781473.1 129280..129708(+) (comGD) [Streptococcus dysgalactiae subsp. equisimilis strain TPCH-A74]
ATGAGACTCAAAAACTGCAACCTTAAAGCTTTCACAATGCTTGAAAGCTTATTAACGCTATCAGTAACAAGTTTTATTGT
CTTGGGGTTATCTGTGCCTGTGACAAGTAGTTATCGAAGGGCTCAGGAACAGCTTTTTTTCACTCGTTTTGAGCACTTTT
ATCGTCACCAACAAAAGTTGGCTATTTTGGAACATGATCAACGGGTTTTGACAATTTCTTCGAAACAAATGCTAGCGGCA
GAGGAGTCGTTAACAATACCTGACTTGATAAGGGTTAAGAATAGCCAGCAATTGGTTATTGATCAAATGGGAGGAAATCA
TTCTTTAGCAAAGATAATATTCGAGACGACTGATCAACGGGTAACTTATCAATTTTATCTAGGGAGTGGAAATTATCAAA
AAACAAGTCAAAGCTTACATCGCTCTTGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGD Streptococcus gordonii str. Challis substr. CH1

43.382

95.775

0.415
  comGD Streptococcus mutans UA140

44.186

90.845

0.401
  comGD Streptococcus mutans UA159

44.186

90.845

0.401
  comGD/cglD Streptococcus mitis NCTC 12261

38.235

95.775

0.366