Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   F1538_RS09060 Genome accession   NZ_CP043771
Coordinates   1819628..1820845 (-) Length   405 a.a.
NCBI ID   WP_013525532.1    Uniprot ID   A0AAV2U474
Organism   Haemophilus influenzae biotype aegyptius strain HE15/F3028     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1814628..1825845
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  F1538_RS09020 (F1538_09030) - 1815801..1816007 (-) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -
  F1538_RS09030 (F1538_09040) - 1816093..1816299 (-) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  F1538_RS09035 (F1538_09045) - 1816374..1816580 (-) 207 WP_013525530.1 heavy-metal-associated domain-containing protein -
  F1538_RS09040 (F1538_09050) cueR 1816657..1817043 (+) 387 WP_005648963.1 Cu(I)-responsive transcriptional regulator -
  F1538_RS09045 (F1538_09055) metJ 1817057..1817374 (-) 318 WP_005631186.1 met regulon transcriptional regulator MetJ -
  F1538_RS09050 (F1538_09060) rho 1817622..1818884 (+) 1263 WP_005666690.1 transcription termination factor Rho -
  F1538_RS09055 (F1538_09065) pilD 1818939..1819631 (-) 693 WP_013525531.1 A24 family peptidase Machinery gene
  F1538_RS09060 (F1538_09070) pilC 1819628..1820845 (-) 1218 WP_013525532.1 type II secretion system F family protein Machinery gene
  F1538_RS09065 (F1538_09075) pilB 1820842..1822236 (-) 1395 WP_013525533.1 GspE/PulE family protein Machinery gene
  F1538_RS09070 (F1538_09080) pilA 1822233..1822682 (-) 450 WP_006996184.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  F1538_RS09075 (F1538_09085) ampD 1822797..1823357 (+) 561 WP_006996183.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  F1538_RS09080 (F1538_09090) corC 1823980..1824879 (+) 900 WP_013525534.1 CNNM family magnesium/cobalt transport protein CorC -

Sequence

Protein


Download         Length: 405 a.a.        Molecular weight: 46062.22 Da        Isoelectric Point: 9.7233

>NTDB_id=385824 F1538_RS09060 WP_013525532.1 1819628..1820845(-) (pilC) [Haemophilus influenzae biotype aegyptius strain HE15/F3028]
MTKKLFYYQGSNALNQKQKGSIIADTKQQAHFQLISRGLTHIKLQQNWQFGAKPKNSEISELLNQLATLLQSAIPLKNSL
QILQQNCTQIMLNEWLERLLQSIESGLAFSQAIEQQGKYLTQQEIQLIQVGEMTGKLAVVCKKIATHRSQSLALQRKLQK
IMLYPSMVLGISLLLTLALLLFIVPQFAEMYSGNNAELPTITAILLSISNFLKQNIGILLFFALSFVLFYYFYLKRQTWF
HQKKNQLISITPIFGTIQKLSRLVNFSHSLQIMLQAGVPLNQALDSFLPRTQTWQTKTLVNDIILDKEVRSILQWVSQGY
AFSDSVSSDLFPMEAQQMLQIGEQSGKLALMLEHIADNYQEKLNHQIDLLSQMLEPLMMVIIGSLIGIIMMGMYLPIFNM
GSVIQ

Nucleotide


Download         Length: 1218 bp        

>NTDB_id=385824 F1538_RS09060 WP_013525532.1 1819628..1820845(-) (pilC) [Haemophilus influenzae biotype aegyptius strain HE15/F3028]
ATGACTAAAAAACTCTTTTATTATCAAGGTAGTAACGCATTAAATCAGAAACAAAAAGGCTCAATTATTGCGGATACGAA
ACAACAAGCGCACTTTCAGTTAATAAGCCGCGGGCTTACTCACATCAAATTACAACAAAACTGGCAATTTGGGGCAAAAC
CCAAAAATTCAGAAATCAGTGAATTACTCAATCAATTAGCGACATTGCTACAGTCCGCAATTCCGTTAAAAAACAGCCTG
CAAATTTTGCAACAAAATTGTACTCAAATTATGCTCAATGAATGGCTTGAACGGCTGCTTCAATCCATTGAATCTGGCTT
AGCATTCTCACAAGCCATTGAACAACAAGGAAAATATCTCACACAACAAGAAATTCAACTGATTCAAGTGGGAGAAATGA
CAGGAAAACTTGCCGTAGTTTGTAAAAAAATAGCCACGCACCGTAGTCAATCTTTGGCTTTACAACGCAAATTACAGAAA
ATTATGTTATATCCCTCAATGGTATTGGGAATTTCTCTATTATTGACACTCGCATTACTGCTTTTTATCGTGCCTCAATT
TGCTGAAATGTACAGTGGCAACAATGCCGAATTACCAACAATAACTGCAATATTGCTCTCTATATCCAATTTTCTTAAGC
AAAATATTGGCATTTTGCTATTTTTCGCTTTGAGTTTTGTTCTATTTTATTACTTTTATCTAAAACGCCAGACTTGGTTT
CATCAAAAGAAAAATCAACTTATTTCTATCACGCCTATTTTTGGCACAATTCAAAAACTTTCACGTTTAGTGAACTTTAG
TCACAGTTTACAAATTATGTTACAGGCTGGCGTACCGCTTAATCAAGCACTAGACAGTTTTCTCCCTCGCACACAAACGT
GGCAAACCAAGACGCTTGTAAATGACATCATATTAGATAAAGAAGTCCGGTCAATTTTACAATGGGTTTCTCAAGGCTAT
GCGTTTTCTGATAGTGTAAGTAGCGATCTTTTCCCGATGGAAGCACAACAAATGTTACAAATTGGCGAGCAAAGCGGAAA
ACTCGCTTTGATGCTAGAGCATATTGCGGATAATTACCAAGAAAAACTTAATCATCAAATTGACTTACTCTCACAAATGC
TAGAACCATTAATGATGGTAATTATCGGCAGTCTGATTGGAATTATTATGATGGGAATGTATTTACCTATCTTTAATATG
GGCTCTGTTATTCAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(266-396)

Type II secretion system (T2SS), protein F (T2SSF)

(63-185)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae 86-028NP

97.537

100

0.978
  pilC Haemophilus influenzae Rd KW20

97.291

100

0.975
  pilC Glaesserella parasuis strain SC1401

38.5

98.765

0.38

Multiple sequence alignment