Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilD   Type   Machinery gene
Locus tag   F1538_RS09055 Genome accession   NZ_CP043771
Coordinates   1818939..1819631 (-) Length   230 a.a.
NCBI ID   WP_013525531.1    Uniprot ID   A0AAV2U3Y4
Organism   Haemophilus influenzae biotype aegyptius strain HE15/F3028     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1813939..1824631
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  F1538_RS09020 (F1538_09030) - 1815801..1816007 (-) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -
  F1538_RS09030 (F1538_09040) - 1816093..1816299 (-) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  F1538_RS09035 (F1538_09045) - 1816374..1816580 (-) 207 WP_013525530.1 heavy-metal-associated domain-containing protein -
  F1538_RS09040 (F1538_09050) cueR 1816657..1817043 (+) 387 WP_005648963.1 Cu(I)-responsive transcriptional regulator -
  F1538_RS09045 (F1538_09055) metJ 1817057..1817374 (-) 318 WP_005631186.1 met regulon transcriptional regulator MetJ -
  F1538_RS09050 (F1538_09060) rho 1817622..1818884 (+) 1263 WP_005666690.1 transcription termination factor Rho -
  F1538_RS09055 (F1538_09065) pilD 1818939..1819631 (-) 693 WP_013525531.1 A24 family peptidase Machinery gene
  F1538_RS09060 (F1538_09070) pilC 1819628..1820845 (-) 1218 WP_013525532.1 type II secretion system F family protein Machinery gene
  F1538_RS09065 (F1538_09075) pilB 1820842..1822236 (-) 1395 WP_013525533.1 GspE/PulE family protein Machinery gene
  F1538_RS09070 (F1538_09080) pilA 1822233..1822682 (-) 450 WP_006996184.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  F1538_RS09075 (F1538_09085) ampD 1822797..1823357 (+) 561 WP_006996183.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26800.82 Da        Isoelectric Point: 8.8532

>NTDB_id=385823 F1538_RS09055 WP_013525531.1 1818939..1819631(-) (pilD) [Haemophilus influenzae biotype aegyptius strain HE15/F3028]
MIYFTMFLLGGIFGIALWFYLSGFITRLQQEIYATYIELFPQNFLPFQSSVSSIQQKKCGHILRYFLSVGVGFIFLQIAF
KDSIFTVWFGLTLLILWAISYLDWHYQLISTTLCLWLLTIGLFGADNNFSLLTLSESIKSAASFFIVFYAIYWIAKFYYG
KEAFGRGDYWLAMALGSFIQLETLPHFLLLASVLGICFSLIHKKKKEFIPFAPFMNLSAVIIYFVKYYWY

Nucleotide


Download         Length: 693 bp        

>NTDB_id=385823 F1538_RS09055 WP_013525531.1 1818939..1819631(-) (pilD) [Haemophilus influenzae biotype aegyptius strain HE15/F3028]
ATGATTTACTTCACAATGTTTTTATTAGGCGGCATCTTCGGGATCGCATTGTGGTTCTACCTATCTGGTTTTATTACCCG
TTTACAGCAAGAGATTTATGCGACTTATATTGAATTATTCCCACAAAACTTTCTGCCATTTCAGTCTAGCGTTTCCTCTA
TTCAACAAAAAAAGTGCGGTCATATTTTGAGGTATTTTTTAAGTGTTGGGGTAGGATTTATATTTTTACAAATTGCCTTC
AAAGATTCTATTTTTACTGTATGGTTCGGACTCACACTTCTTATCCTTTGGGCAATCAGTTATCTTGATTGGCACTATCA
ACTTATTTCTACTACACTCTGTTTATGGTTACTTACAATCGGTTTATTTGGGGCAGACAATAACTTTTCATTGCTTACGT
TATCTGAAAGCATAAAAAGTGCGGCAAGTTTTTTTATTGTTTTCTACGCAATCTATTGGATTGCAAAATTCTATTACGGA
AAAGAAGCCTTTGGACGGGGAGATTATTGGCTAGCAATGGCATTAGGAAGTTTTATTCAGTTAGAAACCTTACCGCACTT
TTTATTATTAGCCTCAGTTCTTGGAATATGTTTTTCGCTTATTCATAAAAAGAAAAAAGAATTTATACCTTTTGCCCCTT
TTATGAACTTATCAGCTGTCATAATTTATTTCGTCAAATATTACTGGTATTAA

Domains

Predicted by InterproScan.

Type IV leader peptidase family (Peptidase_A24)

(92-199)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilD Haemophilus influenzae 86-028NP

90.435

100

0.904
  pilD Haemophilus influenzae Rd KW20

90

100

0.9

Multiple sequence alignment