Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE1/comEA   Type   Machinery gene
Locus tag   F1537_RS09770 Genome accession   NZ_CP043770
Coordinates   1908453..1908800 (+) Length   115 a.a.
NCBI ID   WP_006995651.1    Uniprot ID   A0AAV2TZ57
Organism   Haemophilus influenzae biotype aegyptius strain HE7/F1946     
Function   dsDNA binding (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1903453..1913800
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  F1537_RS09755 (F1537_09765) - 1905199..1906758 (+) 1560 WP_013526121.1 phosphoethanolamine transferase -
  F1537_RS09760 (F1537_09770) lspA 1906828..1907343 (+) 516 WP_006995648.1 signal peptidase II -
  F1537_RS09765 (F1537_09775) ispH 1907340..1908284 (+) 945 WP_006995649.1 4-hydroxy-3-methylbut-2-enyl diphosphate reductase -
  F1537_RS09770 (F1537_09780) comE1/comEA 1908453..1908800 (+) 348 WP_006995651.1 helix-hairpin-helix domain-containing protein Machinery gene
  F1537_RS09775 (F1537_09785) thiB 1909047..1910045 (+) 999 WP_006995652.1 thiamine ABC transporter substrate binding subunit -
  F1537_RS09780 (F1537_09790) thiP 1910050..1911666 (+) 1617 WP_006995653.1 thiamine/thiamine pyrophosphate ABC transporter permease -
  F1537_RS09785 (F1537_09795) thiQ 1911650..1912297 (+) 648 WP_005655984.1 thiamine ABC transporter ATP-binding protein -
  F1537_RS09790 (F1537_09800) bioB 1912410..1913411 (+) 1002 WP_013526120.1 biotin synthase BioB -

Sequence

Protein


Download         Length: 115 a.a.        Molecular weight: 12365.25 Da        Isoelectric Point: 8.0085

>NTDB_id=385795 F1537_RS09770 WP_006995651.1 1908453..1908800(+) (comE1/comEA) [Haemophilus influenzae biotype aegyptius strain HE7/F1946]
MKLMKTLFTSVVLCGALVVSSSFAEEKATEQTAQPVVATQAEAQIALAVVSDKLNINTATASEIQKSLTGIGAKKAEAIV
QYREKHGNFTNAEQLLEVQGIGKATLEKNRDRIIF

Nucleotide


Download         Length: 348 bp        

>NTDB_id=385795 F1537_RS09770 WP_006995651.1 1908453..1908800(+) (comE1/comEA) [Haemophilus influenzae biotype aegyptius strain HE7/F1946]
ATGAAATTAATGAAAACATTATTCACTTCGGTTGTATTGTGTGGTGCGCTGGTTGTTTCTTCGTCTTTTGCTGAGGAAAA
AGCGACAGAACAAACCGCTCAACCTGTTGTAGCAACTCAAGCTGAAGCTCAAATAGCACTAGCCGTAGTGAGCGATAAAT
TGAATATCAACACAGCAACTGCCAGTGAAATTCAAAAATCCCTAACTGGCATTGGTGCGAAAAAAGCGGAAGCTATTGTG
CAATATCGTGAAAAACACGGTAATTTTACTAATGCAGAACAGCTTTTAGAAGTACAAGGAATTGGCAAAGCAACACTAGA
GAAAAATCGTGATCGTATAATCTTTTAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(52-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE1/comEA Haemophilus influenzae Rd KW20

94.643

97.391

0.922
  comEA/comE1 Glaesserella parasuis strain SC1401

58.772

99.13

0.583
  comEA Vibrio cholerae C6706

43.636

95.652

0.417
  comEA Vibrio cholerae strain A1552

43.636

95.652

0.417
  comEA Vibrio campbellii strain DS40M4

40.179

97.391

0.391

Multiple sequence alignment