Detailed information    

insolico Bioinformatically predicted

Overview

Name   pknB   Type   Regulator
Locus tag   FY406_RS05660 Genome accession   NZ_CP043405
Coordinates   1141648..1143510 (+) Length   620 a.a.
NCBI ID   WP_150881013.1    Uniprot ID   -
Organism   Streptococcus ratti strain ATCC 31377     
Function   modulate the activity of ComDE; modulate the activity of VicKR (predicted from homology)   
Competence regulation

Genomic Context

Location: 1136648..1148510
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FY406_RS05645 (FY406_05645) fmt 1138631..1139566 (+) 936 WP_003086433.1 methionyl-tRNA formyltransferase -
  FY406_RS05650 (FY406_05650) rsmB 1139520..1140869 (+) 1350 WP_050990612.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  FY406_RS05655 (FY406_05655) - 1140908..1141651 (+) 744 WP_003086437.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  FY406_RS05660 (FY406_05660) pknB 1141648..1143510 (+) 1863 WP_150881013.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  FY406_RS05665 (FY406_05665) liaF 1143643..1144338 (+) 696 WP_003086440.1 cell wall-active antibiotics response protein LiaF -
  FY406_RS05670 (FY406_05670) - 1144335..1145339 (+) 1005 WP_003086442.1 sensor histidine kinase -
  FY406_RS05675 (FY406_05675) - 1145332..1145973 (+) 642 WP_003086444.1 response regulator transcription factor -
  FY406_RS05680 (FY406_05680) - 1146017..1147429 (+) 1413 WP_003086446.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  FY406_RS05685 (FY406_05685) - 1147416..1147793 (+) 378 WP_003086447.1 S1 RNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 620 a.a.        Molecular weight: 67530.52 Da        Isoelectric Point: 8.4696

>NTDB_id=383584 FY406_RS05660 WP_150881013.1 1141648..1143510(+) (pknB) [Streptococcus ratti strain ATCC 31377]
MIQIGKLFAGRYRILQSIGRGGMADVYLANDLILDNEEVAIKVLRTNYQTDQVAVTRFQREARAMAELNHPNIVAIRDIG
EEDGQQFLAMEYVDGADLKKYIQDHAPLSNAEVIRIMKEVLSAMTLAHQKGIIHRDLKSQNVLLTKDGTAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKPLPSIIAENKNVP
QALENVVIKATAKRLTNRYTSTEEMLQDLRTCLQPSRSREKKLVFNDTADTKPLPKLEQAAGAASAAQSLKNKTTNADRP
ASQPKPKPKVQDKPKKKRRFLSRFLKLFFALVFIGIIILAYLILTKPSTVSVPDVSGNKLSTAKTIIRNSGLKVGQVSKV
EDDSVSDGKVVRTNPSAGTKKREGSSVDIFIASSKGFKMEDYTGQNYQDVIDNLTNNYGVSRKNIVLKEVSSDEYSGGTV
IGQSPKAGKTYRPGSGKKITLRVVEMTMPNLKNTTYEEAVNTLAAMGISAKRIKVYDASDYSTEISSPASSAVVVGQSPY
YGETVSLSSDDDVILYVSESGGSNTHPSSSEATEETTTVTEESTEATTSSDTTAESSVSE

Nucleotide


Download         Length: 1863 bp        

>NTDB_id=383584 FY406_RS05660 WP_150881013.1 1141648..1143510(+) (pknB) [Streptococcus ratti strain ATCC 31377]
ATGATCCAGATTGGCAAATTATTTGCTGGTCGTTATCGAATTCTCCAATCTATCGGACGAGGCGGGATGGCCGATGTTTA
TTTAGCTAACGATCTGATTCTGGATAATGAGGAAGTAGCTATTAAGGTGCTGCGAACCAATTATCAAACAGATCAGGTCG
CTGTGACGCGTTTCCAGCGGGAAGCGCGGGCCATGGCAGAGCTGAATCATCCTAACATTGTTGCCATTCGTGACATTGGA
GAAGAAGACGGTCAGCAGTTCCTTGCAATGGAATATGTTGACGGTGCTGACTTGAAAAAATATATTCAAGATCACGCCCC
TTTATCGAATGCTGAAGTCATTCGTATTATGAAAGAGGTTCTTTCCGCGATGACTCTTGCCCATCAAAAGGGTATTATTC
ACCGGGATTTGAAGTCTCAAAATGTACTTTTAACTAAGGACGGGACGGCCAAAGTAACAGACTTTGGGATTGCTGTAGCC
TTTGCTGAGACCAGCCTGACACAGACCAATTCAATGCTGGGCAGTGTTCATTACCTGTCTCCTGAGCAGGCGCGCGGTTC
AAAAGCAACGGTTCAAAGTGATATCTATGCGATGGGTATCATGCTCTTTGAAATGTTGACCGGGCATATTCCTTATGATG
GTGACAGCGCTGTGACCATTGCTCTGCAGCATTTTCAAAAACCGCTGCCGTCTATCATTGCTGAAAATAAAAATGTTCCT
CAGGCTTTGGAAAATGTTGTTATTAAGGCAACAGCCAAACGTTTGACCAATCGCTACACTTCAACAGAAGAAATGCTGCA
GGATTTAAGAACCTGTCTGCAGCCTAGTCGCAGCCGCGAAAAAAAATTAGTCTTTAATGACACCGCAGATACAAAACCGT
TGCCCAAGCTTGAACAGGCCGCAGGAGCTGCTTCGGCTGCCCAGTCCTTAAAAAATAAGACGACCAATGCGGATAGGCCG
GCCAGTCAGCCCAAGCCTAAACCGAAAGTTCAGGATAAGCCCAAAAAGAAGAGACGCTTCTTGTCTCGCTTCCTCAAGCT
TTTCTTTGCCTTGGTTTTTATCGGTATTATCATTTTAGCCTACCTGATTTTAACCAAGCCGAGTACTGTTTCGGTACCGG
ATGTTTCTGGAAATAAGCTGTCAACGGCTAAAACAATCATCAGAAATTCAGGTTTAAAGGTTGGCCAGGTTAGTAAGGTT
GAAGATGACAGCGTGAGTGATGGCAAAGTTGTTCGCACGAATCCAAGCGCAGGTACTAAAAAGCGTGAAGGATCTAGTGT
TGATATTTTTATAGCCAGCTCTAAAGGCTTTAAGATGGAGGACTACACTGGACAAAATTACCAAGATGTTATTGATAATT
TAACCAATAATTACGGTGTTTCTAGAAAAAATATTGTTCTGAAAGAAGTTTCATCGGATGAGTACAGCGGTGGAACAGTA
ATCGGCCAGTCGCCAAAGGCTGGGAAGACTTATCGTCCCGGCAGCGGCAAAAAGATTACTCTCAGGGTTGTTGAGATGAC
TATGCCGAATCTTAAAAACACAACCTATGAAGAAGCCGTTAATACGTTAGCCGCTATGGGCATTTCAGCAAAACGTATAA
AGGTTTATGATGCTAGCGACTACTCAACAGAAATTTCATCGCCGGCCTCATCAGCTGTGGTTGTAGGCCAAAGTCCTTAT
TACGGAGAGACTGTCAGCCTGTCATCAGATGACGATGTCATCCTCTATGTTTCGGAATCAGGTGGAAGCAATACTCATCC
ATCTTCGTCCGAAGCAACCGAGGAAACAACAACTGTAACAGAAGAGTCAACAGAAGCAACAACCAGTAGTGATACGACTG
CTGAGTCATCAGTATCAGAATAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(370-431)

PASTA domain (PASTA)

(506-578)

PASTA domain (PASTA)

(438-503)

Protein kinase domain (Pkinase)

(12-263)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pknB Streptococcus mutans UA159

87.348

93.065

0.813
  stkP/pknB Streptococcus salivarius strain HSISS4

65.32

95.806

0.626
  stkP Streptococcus pneumoniae TIGR4

51.993

97.097

0.505
  stkP Streptococcus pneumoniae D39

51.827

97.097

0.503
  stkP Streptococcus pneumoniae R6

51.827

97.097

0.503
  stkP Streptococcus pneumoniae Rx1

51.661

97.097

0.502

Multiple sequence alignment