Detailed information NTG0383537

Bioinformatically predicted

Overview

• Name: comFC
• Type: Machinery gene
• Locus tag: FX981_RS19320
• Genome accession: NZ_CP043404
• Coordinates: 2097578..2098234 (+)
• Length: 218 a.a.
• NCBI ID: WP_244948474.1
• Uniprot ID: A0A5C0WI32
• Organism: Bacillus safensis strain PgKB20
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2092578..2103234

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FX981_RS10370 (FX981_02081)	degS	2092704..2093879 (+)	1176	WP_003213166.1	sensor histidine kinase	Regulator
FX981_RS10375 (FX981_02082)	degU	2093944..2094633 (+)	690	WP_008348273.1	two-component system response regulator DegU	Regulator
FX981_RS10380 (FX981_02083)	-	2094849..2095691 (+)	843	WP_024423625.1	DegV family protein	-
FX981_RS10385 (FX981_02084)	comFA	2095812..2097209 (+)	1398	WP_276507389.1	DEAD/DEAH box helicase	Machinery gene
FX981_RS10390 (FX981_02085)	-	2097258..2097551 (+)	294	WP_025093967.1	late competence development ComFB family protein	-
FX981_RS19320 (FX981_02086)	comFC	2097578..2098234 (+)	657	WP_244948474.1	ComF family protein	Machinery gene
FX981_RS10400 (FX981_02087)	-	2098291..2098710 (+)	420	WP_024423621.1	TIGR03826 family flagellar region protein	-
FX981_RS10405 (FX981_02088)	flgM	2098790..2099053 (+)	264	WP_024423620.1	flagellar biosynthesis anti-sigma factor FlgM	-
FX981_RS10410 (FX981_02089)	-	2099072..2099554 (+)	483	WP_149126229.1	flagellar protein FlgN	-
FX981_RS10415 (FX981_02090)	flgK	2099570..2101090 (+)	1521	WP_149126230.1	flagellar hook-associated protein FlgK	-
FX981_RS10420 (FX981_02091)	flgL	2101100..2102008 (+)	909	WP_024423617.1	flagellar hook-associated protein FlgL	-
FX981_RS10425 (FX981_02092)	-	2102055..2102633 (+)	579	WP_024426253.1	DUF6470 family protein	-
FX981_RS10430 (FX981_02093)	fliW	2102662..2103096 (+)	435	WP_024423615.1	flagellar assembly protein FliW	-

Sequence

Protein

• Length: 218 a.a.
• Molecular weight: 24946.05 Da
• Isoelectric Point: 9.7972

>NTDB_id=383537 FX981_RS19320 WP_244948474.1 2097578..2098234(+) (comFC) [Bacillus safensis strain PgKB20]
MPAFTWKSFLLLNDDHLCVACKNHLVKIERPICPTCGRAQSNDQLCQDCNRWNERSDSIKILVKNRSVYTYNELMKDVLA
RFKFRGDTALAELFQKDVQAAFKHSFCIKDPLLIPIPLSHERLKERGFNQSVLIASLLDKPILQPLVKIHQSKQSKKKKN
ERLDQKGLFQIKQTDAIVQRDIILVDDIYTTGATIYDAARILKDAGAKSVSSFTLIRS

Nucleotide

• Length: 657 bp

>NTDB_id=383537 FX981_RS19320 WP_244948474.1 2097578..2098234(+) (comFC) [Bacillus safensis strain PgKB20]
GTGCCTGCTTTTACATGGAAATCATTCCTACTATTAAATGATGATCACCTTTGTGTAGCATGTAAGAATCACTTAGTAAA
GATTGAGCGTCCTATTTGTCCAACATGCGGAAGGGCGCAGTCAAATGACCAATTGTGCCAGGACTGTAACAGATGGAATG
AACGCTCTGATTCTATTAAAATCCTTGTAAAAAATAGGTCAGTTTATACTTACAACGAGTTGATGAAAGATGTCCTTGCC
CGCTTTAAATTTCGGGGTGATACGGCTTTAGCTGAGCTGTTTCAAAAAGATGTACAAGCAGCATTTAAACATTCCTTCTG
CATAAAAGACCCATTGCTGATACCGATTCCTTTAAGTCATGAAAGACTAAAAGAAAGAGGATTTAATCAGTCCGTGTTAA
TCGCTTCTTTGCTAGATAAGCCAATATTGCAGCCACTCGTGAAAATACATCAAAGTAAGCAGTCTAAAAAAAAGAAAAAT
GAACGCCTAGATCAAAAAGGATTGTTTCAAATAAAGCAAACAGATGCGATTGTTCAAAGGGATATTATATTAGTTGATGA
TATCTATACAACGGGAGCAACCATCTATGATGCGGCAAGAATTTTGAAAGACGCAGGTGCTAAAAGTGTTTCTTCTTTTA
CGTTGATACGTAGTTAA

Domains

Predicted by InterproScan.

• Double zinc ribbon domain (DZR_2) (14-49)

• Phosphoribosyl transferase domain (Pribosyltran) (132-216)

3D structure

• AlphaFold DB: A0A5C0WI32

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comFC	Bacillus subtilis subsp. subtilis str. 168	50	99.083	0.495
comFC/cflB	Streptococcus pneumoniae Rx1	36.744	98.624	0.362
comFC/cflB	Streptococcus pneumoniae D39	36.744	98.624	0.362
comFC/cflB	Streptococcus pneumoniae R6	36.744	98.624	0.362
comFC/cflB	Streptococcus pneumoniae TIGR4	36.744	98.624	0.362