Detailed information    

insolico Bioinformatically predicted

Overview

Name   ruvB   Type   Machinery gene
Locus tag   HFV09_RS00340 Genome accession   NZ_CP051138
Coordinates   55485..56483 (+) Length   332 a.a.
NCBI ID   WP_002986679.1    Uniprot ID   A2RC05
Organism   Streptococcus pyogenes strain 4063-05     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 50485..61483
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HFV09_RS00325 - 51531..52415 (+) 885 WP_011528141.1 HNH endonuclease -
  HFV09_RS00330 purB 52924..54216 (+) 1293 WP_011528142.1 adenylosuccinate lyase -
  HFV09_RS00335 comR 54348..55259 (+) 912 WP_011528143.1 transcriptional regulator Rgg4/ComR Regulator
  HFV09_RS09680 comS 55343..55438 (+) 96 WP_198462994.1 quorum-sensing system DWW-type pheromone Regulator
  HFV09_RS00340 ruvB 55485..56483 (+) 999 WP_002986679.1 Holliday junction branch migration DNA helicase RuvB Machinery gene
  HFV09_RS00345 - 56621..57058 (+) 438 WP_002987727.1 low molecular weight protein-tyrosine-phosphatase -
  HFV09_RS00350 - 57082..57483 (+) 402 WP_002986671.1 MORN repeat-containing protein -
  HFV09_RS00355 - 57480..59255 (+) 1776 WP_011528145.1 acyltransferase family protein -

Sequence

Protein


Download         Length: 332 a.a.        Molecular weight: 37565.11 Da        Isoelectric Point: 5.3005

>NTDB_id=382655 HFV09_RS00340 WP_002986679.1 55485..56483(+) (ruvB) [Streptococcus pyogenes strain 4063-05]
MARILDNNVMGNEEFSDRTLRPQYLHEYIGQDKVKEQFAIFIEAAKRRDESLDHVLLFGPPGLGKTTMAFVIANELGVNL
KQTSGPAVEKAGDLVAILNELEPGDILFIDEIHRMPMSVEEVLYSAMEDFYIDIMIGAGDTSRSIHLDLPPFTLIGATTR
AGMLSNPLRARFGITGHMEYYQEKDLTEIVERTATIFEIKIDHEAARKLACRSRGTPRIANRLLKRVRDYAQIIGDGIIT
AQITDRALTMLDVDREGLDYIDQKILRTMIEMYQGGPVGLGTLSVNIAEERNTVEEMYEPYLIQKGFLMRTRTGRVATQK
AYRHLGYPYQNT

Nucleotide


Download         Length: 999 bp        

>NTDB_id=382655 HFV09_RS00340 WP_002986679.1 55485..56483(+) (ruvB) [Streptococcus pyogenes strain 4063-05]
ATGGCTAGAATTTTAGACAATAATGTAATGGGAAATGAGGAGTTTTCGGATCGGACTCTTCGCCCTCAATATCTACACGA
ATATATTGGACAAGATAAAGTTAAGGAACAATTCGCAATTTTTATAGAAGCAGCTAAAAGACGTGACGAATCTTTAGACC
ATGTTTTATTATTTGGACCTCCAGGACTGGGAAAAACAACAATGGCATTTGTGATTGCCAATGAATTGGGAGTTAATTTA
AAGCAAACTTCAGGTCCTGCCGTTGAGAAAGCTGGAGATTTGGTAGCTATTTTAAATGAATTAGAACCAGGGGATATTTT
GTTTATTGATGAAATTCACCGCATGCCAATGTCTGTCGAGGAAGTACTATATAGTGCTATGGAAGACTTCTATATTGATA
TTATGATTGGCGCTGGAGATACTAGTCGTAGTATTCATTTGGATCTGCCTCCATTTACATTGATTGGTGCTACTACACGT
GCAGGCATGTTATCTAATCCCCTCAGAGCTCGTTTTGGTATCACTGGTCACATGGAATACTATCAAGAAAAGGATTTGAC
AGAGATTGTGGAGCGTACAGCTACTATTTTTGAAATAAAAATAGACCATGAAGCTGCACGGAAATTAGCTTGTCGCAGTA
GAGGAACGCCCCGCATTGCTAATCGATTACTAAAACGAGTGCGTGACTATGCTCAAATTATTGGTGATGGCATCATAACG
GCTCAAATAACTGATAGAGCTTTGACTATGTTAGATGTTGACCGCGAAGGTCTCGATTACATTGATCAGAAAATTTTACG
AACGATGATTGAGATGTATCAGGGAGGACCAGTTGGTTTGGGGACATTATCTGTGAATATTGCCGAGGAGCGTAATACAG
TTGAAGAGATGTATGAACCCTACTTAATTCAAAAAGGCTTTCTCATGCGAACACGAACAGGTCGTGTAGCGACGCAAAAG
GCTTATCGTCATCTTGGCTATCCCTATCAAAACACTTAA

Domains

Predicted by InterProScan.

RuvB C-terminal winged helix domain (WHD_RuvB)

(256-325)

RuvB AAA lid domain (AAA_lid_4)

(181-254)

Holliday junction DNA helicase RuvB P-loop domain (RuvB_N)

(20-178)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A2RC05

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ruvB Streptococcus pneumoniae R6

84.848

99.398

0.843
  ruvB Streptococcus pneumoniae D39

84.848

99.398

0.843
  ruvB Streptococcus pneumoniae TIGR4

84.545

99.398

0.84
  ruvB Bacillus subtilis subsp. subtilis str. 168

58.824

97.289

0.572
  ruvB Helicobacter pylori 26695

48.936

99.096

0.485
  ruvB Synechocystis sp. PCC 6803

50.16

94.277

0.473