Detailed information    

insolico Bioinformatically predicted

Overview

Name   comM   Type   Machinery gene
Locus tag   FXN59_RS04730 Genome accession   NZ_CP043004
Coordinates   887552..888256 (-) Length   234 a.a.
NCBI ID   WP_148328291.1    Uniprot ID   -
Organism   Aggregatibacter actinomycetemcomitans strain HK_973     
Function   require for natural transformation (predicted from homology)   
Unclear

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 862598..897642 887552..888256 within 0


Gene organization within MGE regions


Location: 862598..897642
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FXN59_RS04555 (FXN59_04555) - 862598..863632 (-) 1035 WP_262404614.1 site-specific integrase -
  FXN59_RS04560 (FXN59_04560) - 863518..863841 (-) 324 WP_233113734.1 helix-turn-helix domain-containing protein -
  FXN59_RS04565 (FXN59_04565) - 863881..864195 (-) 315 WP_015971210.1 hypothetical protein -
  FXN59_RS04575 (FXN59_04575) - 864462..864737 (+) 276 Protein_869 helix-turn-helix transcriptional regulator -
  FXN59_RS04580 (FXN59_04580) - 864795..865817 (+) 1023 WP_187387016.1 N-acetyltransferase -
  FXN59_RS04585 (FXN59_04585) - 865792..866067 (-) 276 WP_148327382.1 hypothetical protein -
  FXN59_RS04590 (FXN59_04590) - 866406..866762 (+) 357 WP_148327383.1 DUF2513 domain-containing protein -
  FXN59_RS04595 (FXN59_04595) - 866915..867094 (+) 180 WP_019518459.1 hypothetical protein -
  FXN59_RS04600 (FXN59_04600) - 867094..867507 (+) 414 WP_019518460.1 hypothetical protein -
  FXN59_RS04605 (FXN59_04605) - 867601..867825 (+) 225 WP_005545968.1 hypothetical protein -
  FXN59_RS04610 (FXN59_04610) - 868044..868286 (+) 243 WP_262404602.1 hypothetical protein -
  FXN59_RS12450 - 868283..868741 (+) 459 WP_262404603.1 helix-turn-helix domain-containing protein -
  FXN59_RS04620 (FXN59_04620) - 868727..869146 (-) 420 WP_151294346.1 type II toxin-antitoxin system HicB family antitoxin -
  FXN59_RS04625 (FXN59_04625) - 869198..869380 (-) 183 WP_005567475.1 type II toxin-antitoxin system HicA family toxin -
  FXN59_RS04630 (FXN59_04630) - 869634..869852 (+) 219 WP_151294348.1 hypothetical protein -
  FXN59_RS04635 (FXN59_04635) - 869928..870695 (-) 768 WP_151294074.1 IS5-like element ISAac2 family transposase -
  FXN59_RS04640 (FXN59_04640) - 870716..871180 (+) 465 WP_151294350.1 hypothetical protein -
  FXN59_RS12455 - 871393..871749 (+) 357 Protein_883 baseplate J/gp47 family protein -
  FXN59_RS04650 (FXN59_04650) rbsA 871978..873435 (-) 1458 WP_151294352.1 ribose ABC transporter ATP-binding protein RbsA -
  FXN59_RS04655 (FXN59_04655) rbsD 873446..873865 (-) 420 WP_148324370.1 D-ribose pyranase -
  FXN59_RS04660 (FXN59_04660) rppH 874085..874684 (+) 600 WP_148324373.1 RNA pyrophosphohydrolase -
  FXN59_RS04665 (FXN59_04665) - 874687..875484 (+) 798 WP_148324376.1 sulfite exporter TauE/SafE family protein -
  FXN59_RS04670 (FXN59_04670) lgt 875493..876290 (+) 798 WP_148324379.1 prolipoprotein diacylglyceryl transferase -
  FXN59_RS04675 (FXN59_04675) - 876287..877138 (+) 852 WP_151294354.1 thymidylate synthase -
  FXN59_RS04685 (FXN59_04685) tadA 877462..877989 (+) 528 WP_148325832.1 tRNA adenosine(34) deaminase TadA -
  FXN59_RS04690 (FXN59_04690) - 878221..878619 (-) 399 WP_151294356.1 hypothetical protein -
  FXN59_RS04695 (FXN59_04695) - 878929..880101 (-) 1173 WP_151294358.1 DUF6396 domain-containing protein -
  FXN59_RS04700 (FXN59_04700) - 880172..881896 (-) 1725 WP_262404604.1 phospholipase D-like domain-containing protein -
  FXN59_RS12460 - 881908..882066 (-) 159 WP_005579457.1 hypothetical protein -
  FXN59_RS04705 (FXN59_04705) - 882098..882418 (-) 321 WP_151294360.1 hypothetical protein -
  FXN59_RS04710 (FXN59_04710) - 882601..883284 (-) 684 WP_005542522.1 2,3-diphosphoglycerate-dependent phosphoglycerate mutase -
  FXN59_RS04715 (FXN59_04715) - 883590..885248 (+) 1659 WP_005595409.1 phospho-sugar mutase -
  FXN59_RS04720 (FXN59_04720) envC 885457..886716 (+) 1260 WP_148327243.1 murein hydrolase activator EnvC -
  FXN59_RS04725 (FXN59_04725) - 886722..887540 (+) 819 WP_392388690.1 divergent polysaccharide deacetylase family protein -
  FXN59_RS04730 (FXN59_04730) comM 887552..888256 (-) 705 WP_148328291.1 ATP-binding protein Machinery gene
  FXN59_RS04735 (FXN59_04735) - 888391..889053 (+) 663 WP_148327240.1 TnsA endonuclease N-terminal domain-containing protein -
  FXN59_RS04740 (FXN59_04740) - 889046..890965 (+) 1920 WP_151294362.1 Mu transposase C-terminal domain-containing protein -
  FXN59_RS04745 (FXN59_04745) - 890965..891858 (+) 894 WP_005541478.1 TniB family NTP-binding protein -
  FXN59_RS04750 (FXN59_04750) - 891816..892898 (+) 1083 WP_151294364.1 TniQ family protein -
  FXN59_RS04755 (FXN59_04755) - 892931..894286 (+) 1356 WP_187387017.1 hypothetical protein -
  FXN59_RS04760 (FXN59_04760) - 894314..895081 (-) 768 WP_151294074.1 IS5-like element ISAac2 family transposase -
  FXN59_RS04765 (FXN59_04765) - 895358..895576 (+) 219 WP_019518360.1 hypothetical protein -
  FXN59_RS04770 (FXN59_04770) - 895712..896020 (-) 309 WP_019518359.1 helix-turn-helix transcriptional regulator -
  FXN59_RS12465 - 896062..896904 (+) 843 WP_262404605.1 recombinase family protein -
  FXN59_RS12470 - 897007..897642 (+) 636 WP_233438889.1 hypothetical protein -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 26224.18 Da        Isoelectric Point: 10.0496

>NTDB_id=380143 FXN59_RS04730 WP_148328291.1 887552..888256(-) (comM) [Aggregatibacter actinomycetemcomitans strain HK_973]
MPLICNFDSGTIPKPGEISLAHNGVLFLDELPEFERKVLDALRQPLESGEIIISRANAKIQFPAKFQLIAAMNPSPTGHY
QGTHNRTSPQQVMRYLNRLSGPFLDRFDLSIEVPLLPQGSLQNIGDRGESSATVREKVLKTRAIQLQRASKINAHLNSKE
IERDCKLTDKNALFLENALTKLGLSVRAYHRILKVSRTIADLDGEQHINQRHLAEALGYRAMDRLLQKLAKNSA

Nucleotide


Download         Length: 705 bp        

>NTDB_id=380143 FXN59_RS04730 WP_148328291.1 887552..888256(-) (comM) [Aggregatibacter actinomycetemcomitans strain HK_973]
ATGCCACTTATTTGTAACTTTGACAGCGGCACGATCCCCAAACCGGGCGAAATTTCCCTCGCTCACAATGGTGTGTTATT
TTTAGATGAATTGCCCGAATTTGAACGCAAAGTGCTGGACGCGCTGCGTCAACCATTGGAAAGTGGCGAAATTATTATTT
CCCGTGCCAACGCGAAGATTCAATTTCCGGCAAAATTTCAACTGATTGCCGCGATGAACCCTAGCCCGACAGGGCATTAT
CAAGGCACGCATAATCGCACCTCACCACAACAAGTTATGCGTTATCTGAATCGTTTGTCCGGCCCTTTTTTAGATCGCTT
CGATTTATCCATTGAAGTGCCCTTATTGCCACAAGGTAGCTTACAAAATATCGGCGATCGTGGCGAATCCAGCGCAACGG
TGCGAGAAAAAGTCCTGAAAACCCGTGCCATTCAACTTCAGCGCGCCAGCAAAATTAATGCCCATTTAAATAGCAAAGAA
ATCGAACGGGACTGCAAACTTACCGACAAAAACGCACTATTCCTGGAAAATGCCCTGACTAAACTGGGGCTTTCCGTACG
GGCGTACCACCGCATACTGAAAGTGTCCCGCACCATTGCCGATTTAGATGGAGAACAACACATCAACCAGCGCCATCTGG
CCGAAGCTCTGGGTTATCGGGCAATGGACAGGTTGTTGCAAAAATTGGCGAAAAACTCGGCATAA

Domains

Predicted by InterproScan.

Magnesium chelatase, subunit ChlI (Mg_chelatase)

(9-118)

Magnesium chelatase, subunit ChlI C-terminal (Mg_chelatase_C)

(128-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comM Haemophilus influenzae Rd KW20

86.087

98.291

0.846
  comM Glaesserella parasuis strain SC1401

80.603

99.145

0.799
  comM Vibrio cholerae strain A1552

66.968

94.444

0.632
  comM Vibrio campbellii strain DS40M4

64.706

94.444

0.611
  RA0C_RS07335 Riemerella anatipestifer ATCC 11845 = DSM 15868

52.444

96.154

0.504
  comM Legionella pneumophila str. Paris

52.336

91.453

0.479
  comM Legionella pneumophila strain ERS1305867

52.336

91.453

0.479

Multiple sequence alignment