Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   HB740_RS22620 Genome accession   NZ_CP050325
Coordinates   4869547..4870761 (-) Length   404 a.a.
NCBI ID   WP_003112721.1    Uniprot ID   Q9I5N8
Organism   Pseudomonas aeruginosa strain DVT425     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 4864547..4875761
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HB740_RS22610 (HB740_22650) - 4866729..4867841 (-) 1113 WP_003112720.1 substrate-binding domain-containing protein -
  HB740_RS22615 (HB740_22655) lapA 4867927..4869033 (-) 1107 WP_003112123.1 alkaline phosphatase LapA -
  HB740_RS22620 (HB740_22660) pilC 4869547..4870761 (-) 1215 WP_003112721.1 type II secretion system inner membrane protein GspF Machinery gene
  HB740_RS22625 (HB740_22665) pilB 4870761..4872170 (-) 1410 WP_003112722.1 type II secretion system ATPase GspE Machinery gene
  HB740_RS22630 (HB740_22670) gspD 4872167..4874578 (-) 2412 WP_174707909.1 type II secretion system secretin GspD -
  HB740_RS22635 (HB740_22675) gspM 4874575..4875168 (-) 594 WP_034012946.1 type II secretion system protein M -

Sequence

Protein


Download         Length: 404 a.a.        Molecular weight: 43409.42 Da        Isoelectric Point: 9.3769

>NTDB_id=378485 HB740_RS22620 WP_003112721.1 4869547..4870761(-) (pilC) [Pseudomonas aeruginosa strain DVT425]
MQTFRYEAADAQGRIETGTLEADSQRGALGQLRARGLTPLEVREQAGGGTGQGAGALFAPRLSDGDLAWATRQLASLLAA
SLPLEAALSATLDQAERKHIAQTLSAVRSDVRGGMRLADALAARPRDFPEIYRALVAAGEESGDLAQVMERLADYIEERN
ALRGKILTAFIYPAVVGVVSIGIVIFLLGYVVPQVVSAFSQARQDLPALTRAMLQASDFVRAWGWLCAGAIGSAYWGWRL
YLRDPQARLGWHRRVLRLPLLGRFVLGVNTARFASTLAILGSAGVPLLRALDAARQTLANDCLAQAVEEATAQVREGVSL
ASALRTRQVFPPILTHLIASGEKTGALPPMLDRAAQTLSRDIERRAMGMTALLEPLMIVVMGGVVLTIVMAVLMPIIEMN
QLVQ

Nucleotide


Download         Length: 1215 bp        

>NTDB_id=378485 HB740_RS22620 WP_003112721.1 4869547..4870761(-) (pilC) [Pseudomonas aeruginosa strain DVT425]
ATGCAGACCTTCCGTTACGAAGCCGCCGACGCCCAGGGCCGGATCGAGACCGGCACCCTGGAGGCGGACAGCCAGCGTGG
CGCCCTCGGCCAACTGCGCGCCCGCGGCCTGACCCCGCTGGAGGTCCGCGAGCAGGCTGGCGGCGGGACCGGGCAAGGGG
CGGGCGCGCTGTTCGCCCCGCGCCTGTCCGACGGCGACCTGGCCTGGGCCACCCGCCAGCTGGCCAGCCTGCTGGCCGCT
AGCCTGCCGCTGGAGGCGGCGCTGAGCGCCACCCTCGACCAGGCCGAGCGCAAGCACATCGCCCAGACCCTGAGCGCCGT
GCGCAGCGACGTGCGCGGCGGCATGCGCCTGGCCGACGCCCTTGCCGCACGGCCGCGGGACTTCCCGGAAATCTACCGGG
CGCTGGTGGCTGCGGGCGAGGAGTCCGGCGACCTGGCCCAGGTGATGGAGCGCCTGGCCGACTACATCGAGGAACGCAAC
GCCCTGCGCGGCAAGATCCTCACCGCGTTCATCTACCCGGCGGTGGTCGGCGTGGTCTCCATCGGCATCGTCATTTTCCT
CCTCGGCTACGTGGTGCCGCAGGTGGTCAGCGCCTTCTCCCAGGCGCGCCAGGACCTGCCGGCGCTGACCCGGGCGATGC
TCCAGGCCAGCGACTTCGTGCGCGCCTGGGGCTGGCTCTGCGCCGGCGCCATCGGTAGCGCTTACTGGGGCTGGCGCTTG
TACCTGCGCGACCCGCAGGCGCGGCTCGGCTGGCACCGGCGAGTGCTGCGCCTGCCTCTGCTCGGTCGCTTCGTGCTCGG
GGTGAACACCGCGCGCTTCGCCTCCACCCTGGCGATCCTCGGCAGCGCCGGCGTACCGCTGCTGCGCGCGCTCGATGCGG
CGCGCCAGACGCTGGCCAACGACTGCCTCGCGCAGGCGGTGGAGGAGGCCACCGCGCAGGTTCGCGAAGGTGTCTCGCTG
GCCTCGGCGCTGCGCACGCGGCAGGTGTTCCCGCCGATCCTCACCCACCTGATCGCCAGCGGCGAGAAGACCGGTGCGCT
GCCGCCGATGCTCGACCGCGCGGCGCAGACCCTGTCGCGCGACATCGAGCGCCGCGCCATGGGCATGACCGCGTTGCTCG
AGCCGCTGATGATCGTGGTCATGGGCGGGGTGGTGCTGACCATCGTGATGGCGGTGCTGATGCCGATCATCGAGATGAAC
CAACTGGTCCAGTAG

Domains

Predicted by InterProScan.

Type II secretion system (T2SS), protein F (T2SSF)

(273-395)

Type II secretion system (T2SS), protein F (T2SSF)

(71-193)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9I5N8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Thermus thermophilus HB27

36.386

100

0.364

Multiple sequence alignment