Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   FR729_RS12390 Genome accession   NZ_CP042449
Coordinates   2637313..2637945 (+) Length   210 a.a.
NCBI ID   WP_005381432.1    Uniprot ID   U2ZZI4
Organism   Vibrio alginolyticus strain FA2     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2632313..2642945
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FR729_RS12365 (FR729_12740) - 2632332..2634251 (+) 1920 WP_136977022.1 ABC transporter ATP-binding protein -
  FR729_RS12370 (FR729_12745) - 2634248..2634736 (+) 489 WP_167415493.1 TIGR02444 family protein -
  FR729_RS12375 (FR729_12750) - 2634824..2635831 (+) 1008 WP_132937307.1 hydrolase -
  FR729_RS12380 (FR729_12755) - 2635865..2636077 (+) 213 WP_005382815.1 YheU family protein -
  FR729_RS12385 (FR729_12760) - 2636203..2637072 (+) 870 WP_005381434.1 phosphoribulokinase -
  FR729_RS12390 (FR729_12765) crp 2637313..2637945 (+) 633 WP_005381432.1 cAMP-activated global transcriptional regulator CRP Regulator
  FR729_RS12395 (FR729_12770) - 2638082..2638873 (-) 792 WP_042523639.1 DUF1338 domain-containing protein -
  FR729_RS12400 (FR729_12775) astD 2639122..2640579 (-) 1458 WP_005381424.1 succinylglutamate-semialdehyde dehydrogenase -
  FR729_RS12405 (FR729_12780) astA 2640608..2641627 (-) 1020 WP_005381422.1 arginine N-succinyltransferase -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23665.48 Da        Isoelectric Point: 7.8388

>NTDB_id=377955 FR729_RS12390 WP_005381432.1 2637313..2637945(+) (crp) [Vibrio alginolyticus strain FA2]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHAGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEED
QERTAWVRAKSPCEVAEISFKKFRQLIQVNPDILMRLSAQMARRLQVTSQKVGDLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEEQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=377955 FR729_RS12390 WP_005381432.1 2637313..2637945(+) (crp) [Vibrio alginolyticus strain FA2]
ATGGTTCTAGGTAAACCTCAAACCGACCCAACATTAGAGTGGTTTCTTTCACACTGTCATATTCATAAGTACCCTTCAAA
GAGCACGCTAATTCACGCGGGCGAAAAGGCAGAAACTTTGTACTACATCGTTAAAGGTTCTGTTGCGGTTCTTATCAAAG
ACGAAGAAGGTAAGGAGATGATCCTTTCTTACCTAAACCAAGGAGACTTTATTGGTGAACTTGGTCTATTCGAGGAAGAC
CAAGAGCGCACAGCTTGGGTTCGTGCTAAATCTCCTTGTGAAGTTGCTGAAATTTCTTTCAAGAAGTTCCGTCAGCTTAT
CCAAGTAAACCCAGACATCCTAATGCGTCTTTCTGCGCAGATGGCTCGTCGTCTTCAAGTAACTAGCCAAAAAGTGGGTG
ACCTGGCGTTCCTAGACGTAACTGGTCGTATCGCTCAGACGCTTCTGAACCTTGCAAAACAACCAGACGCAATGACTCAC
CCAGACGGCATGCAAATCAAGATCACTCGTCAAGAAATCGGTCAAATTGTTGGCTGTTCTCGTGAGACAGTAGGTCGTAT
CTTGAAGATGCTAGAAGAGCAGAACCTAATCTCTGCTCACGGTAAAACCATCGTGGTTTACGGTACTCGTTAA

Domains

Predicted by InterproScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB U2ZZI4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

98.095

100

0.981
  crp Haemophilus influenzae Rd KW20

75.49

97.143

0.733
  crp Acinetobacter baumannii D1279779

47.826

98.571

0.471

Multiple sequence alignment