Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   FGL78_RS04615 Genome accession   NZ_CP042390
Coordinates   870877..872016 (+) Length   379 a.a.
NCBI ID   WP_146976131.1    Uniprot ID   -
Organism   Leuconostoc lactis strain CBA3626     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 865877..877016
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL78_RS04595 (FGL78_04595) yycF 866038..866745 (+) 708 WP_029510319.1 response regulator YycF -
  FGL78_RS04600 (FGL78_04600) walK 866841..868712 (+) 1872 WP_146976127.1 cell wall metabolism sensor histidine kinase WalK -
  FGL78_RS04605 (FGL78_04605) yycH 868702..870012 (+) 1311 WP_146976129.1 two-component system activity regulator YycH -
  FGL78_RS04610 (FGL78_04610) yycI 870038..870814 (+) 777 WP_029510322.1 two-component system regulatory protein YycI -
  FGL78_RS04615 (FGL78_04615) htrA 870877..872016 (+) 1140 WP_146976131.1 trypsin-like peptidase domain-containing protein Regulator
  FGL78_RS04620 (FGL78_04620) rlmH 872668..873147 (+) 480 WP_010000997.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  FGL78_RS09580 - 873219..873362 (-) 144 WP_010000998.1 hypothetical protein -
  FGL78_RS04625 (FGL78_04625) mutY 873486..874502 (+) 1017 WP_146976134.1 A/G-specific adenine glycosylase -
  FGL78_RS04630 (FGL78_04630) - 874508..875611 (+) 1104 WP_146976136.1 AI-2E family transporter -
  FGL78_RS04635 (FGL78_04635) - 875657..876043 (+) 387 WP_146976139.1 DUF6508 domain-containing protein -
  FGL78_RS04650 (FGL78_04650) - 876437..876772 (+) 336 WP_048700375.1 PadR family transcriptional regulator -

Sequence

Protein


Download         Length: 379 a.a.        Molecular weight: 39302.62 Da        Isoelectric Point: 8.9011

>NTDB_id=377627 FGL78_RS04615 WP_146976131.1 870877..872016(+) (htrA) [Leuconostoc lactis strain CBA3626]
MADKSLTKIIVTGAVAGVLGGGAMLYGQRGLEDMQQSQQKVTTKADKTVTIAKDATATSAYNKVSDAVVSVLNFSQTGKD
SFQEASEGSGVIYKKSGDAAYVVTNNHVINGAAQIQVMLHDGQKVTATLVGKDAMTDLAVLNIAADKVTTTAAFGDSNKI
QVGQKVLAIGSPLGSQYASSVTEGIISAKKRLVESSSEDGQNYGGSTVIQTDAAINPGNSGGPLINFAGQVIGINSMKLS
SSASGTSVEGMGFAIPSNQVVDIVNKLVKYGQVTRPAIGIGLVELSAVTVDDQKSLLKIPDTVKGGVVVMSLTPNGPAAK
AGIQKYDVITGIDGKTVTGQADLREELYKHDLNDTVTITYYHQAEKKTVKVKLTQKLGS

Nucleotide


Download         Length: 1140 bp        

>NTDB_id=377627 FGL78_RS04615 WP_146976131.1 870877..872016(+) (htrA) [Leuconostoc lactis strain CBA3626]
ATGGCAGATAAATCATTAACAAAAATTATCGTAACCGGCGCAGTTGCTGGCGTTCTTGGTGGTGGGGCAATGTTGTATGG
GCAGCGCGGCTTAGAAGATATGCAACAATCACAACAAAAAGTCACCACCAAGGCTGATAAGACGGTGACAATTGCCAAGG
ATGCAACGGCGACTTCAGCTTACAATAAAGTGTCAGATGCGGTTGTTTCTGTGTTGAATTTCTCTCAAACAGGCAAAGAT
TCGTTTCAAGAAGCATCTGAAGGTTCAGGCGTGATTTACAAGAAGTCTGGGGATGCGGCCTATGTGGTGACGAATAATCA
CGTGATTAACGGAGCAGCTCAAATTCAAGTCATGTTACATGACGGGCAAAAGGTGACGGCTACGTTGGTTGGAAAAGATG
CCATGACGGACTTAGCGGTGTTAAATATTGCTGCCGATAAGGTTACCACAACGGCAGCATTTGGTGATTCCAATAAGATC
CAAGTAGGTCAGAAAGTTTTGGCTATTGGCTCGCCGTTAGGGTCACAATATGCGTCATCGGTGACAGAAGGGATTATTTC
GGCTAAGAAGCGTTTGGTGGAGTCTTCTTCTGAAGATGGGCAAAATTATGGGGGCTCAACGGTTATTCAAACCGATGCGG
CCATTAACCCTGGTAATTCCGGTGGTCCATTAATTAATTTTGCTGGCCAAGTGATTGGGATTAACTCAATGAAACTCTCT
TCTTCTGCTTCTGGCACGAGTGTTGAAGGGATGGGATTTGCTATTCCGTCAAATCAAGTGGTAGATATTGTTAATAAGTT
GGTCAAGTATGGCCAAGTGACGCGTCCAGCTATTGGCATTGGATTAGTTGAATTATCAGCTGTGACGGTTGATGACCAAA
AGTCGCTGTTGAAGATCCCAGATACAGTTAAGGGCGGCGTTGTTGTCATGAGTTTGACCCCTAATGGACCAGCGGCTAAA
GCTGGTATTCAGAAATACGACGTAATTACTGGAATTGATGGTAAAACCGTGACGGGGCAAGCTGACTTGCGTGAAGAATT
ATATAAGCATGATCTTAATGATACGGTCACAATTACTTATTATCACCAAGCAGAGAAAAAGACTGTTAAAGTTAAATTAA
CACAAAAATTAGGAAGTTAA

Domains

Predicted by InterproScan.

Trypsin-like peptidase domain (Trypsin_2)

(88-234)

PDZ domain (PDZ_2)

(276-373)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mitis NCTC 12261

47.273

100

0.48
  htrA Streptococcus pneumoniae Rx1

46.53

100

0.478
  htrA Streptococcus pneumoniae D39

46.53

100

0.478
  htrA Streptococcus pneumoniae R6

46.53

100

0.478
  htrA Streptococcus pneumoniae TIGR4

46.53

100

0.478
  htrA Streptococcus gordonii str. Challis substr. CH1

47.23

100

0.472
  htrA Streptococcus mutans UA159

49.118

89.71

0.441

Multiple sequence alignment