Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   FGL83_RS02600 Genome accession   NZ_CP042387
Coordinates   516724..517863 (-) Length   379 a.a.
NCBI ID   WP_147000822.1    Uniprot ID   -
Organism   Leuconostoc lactis strain CBA3625     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 511724..522863
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL83_RS02565 (FGL83_02565) - 511967..512302 (-) 336 WP_010004867.1 PadR family transcriptional regulator -
  FGL83_RS02580 (FGL83_02580) - 512696..513082 (-) 387 WP_147000818.1 DUF6508 domain-containing protein -
  FGL83_RS02585 (FGL83_02585) - 513128..514231 (-) 1104 WP_147000819.1 AI-2E family transporter -
  FGL83_RS02590 (FGL83_02590) mutY 514237..515253 (-) 1017 WP_147000820.1 A/G-specific adenine glycosylase -
  FGL83_RS09125 - 515377..515520 (+) 144 WP_186727233.1 hypothetical protein -
  FGL83_RS02595 (FGL83_02595) rlmH 515593..516072 (-) 480 WP_147000821.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  FGL83_RS02600 (FGL83_02600) htrA 516724..517863 (-) 1140 WP_147000822.1 S1C family serine protease Regulator
  FGL83_RS02605 (FGL83_02605) yycI 517926..518702 (-) 777 WP_147000823.1 two-component system regulatory protein YycI -
  FGL83_RS02610 (FGL83_02610) yycH 518728..520038 (-) 1311 WP_147000824.1 two-component system activity regulator YycH -
  FGL83_RS02615 (FGL83_02615) walK 520028..521899 (-) 1872 WP_048700365.1 cell wall metabolism sensor histidine kinase WalK -
  FGL83_RS02620 (FGL83_02620) yycF 521996..522703 (-) 708 WP_029510319.1 response regulator YycF -

Sequence

Protein


Download         Length: 379 a.a.        Molecular weight: 39314.72 Da        Isoelectric Point: 9.1970

>NTDB_id=377561 FGL83_RS02600 WP_147000822.1 516724..517863(-) (htrA) [Leuconostoc lactis strain CBA3625]
MADKSLTKIIVTGAIAGVLGGGAMLYGQRGLEDMQQSQQKVTTKADKTVTIAKDATATSAYNKVSDAVVSVLNFSQTGKD
SFQEASEGSGVIYKKSGDAAYVVTNNHVINGAAQIQVMLHDGQKVTATLVGKDAMTDLAVLKIAADKVTTTAAFGDSNKI
QVGQKVLAIGSPLGAQYASSVTEGIISAKKRLVESSSEDGQNYGGSTVIQTDAAINPGNSGGPLINFAGQVIGINSMKLS
SSASGTSVEGMGFAIPSNQVVDIVNKLVKYGQVTRPAIGIGLVELSAVTVDDQKSLLKIPDTVKGGVVVMSLTPNGPAAK
AGIQKYDVITGIDGKTVTGQADLREELYKHDLNDTVTITYYHQAEKKTVKVKLTQKLGS

Nucleotide


Download         Length: 1140 bp        

>NTDB_id=377561 FGL83_RS02600 WP_147000822.1 516724..517863(-) (htrA) [Leuconostoc lactis strain CBA3625]
ATGGCAGATAAATCATTAACAAAAATTATCGTAACCGGCGCAATTGCTGGTGTTCTTGGTGGTGGGGCGATGTTGTATGG
GCAGCGCGGCTTAGAAGATATGCAACAATCACAACAAAAAGTCACCACCAAGGCTGATAAGACGGTGACAATTGCCAAGG
ATGCAACGGCGACTTCAGCTTACAATAAAGTGTCAGATGCGGTTGTTTCTGTATTGAATTTCTCTCAAACGGGCAAAGAT
TCTTTTCAAGAAGCGTCTGAAGGCTCAGGCGTGATTTACAAGAAGTCTGGGGATGCGGCCTATGTGGTGACGAATAATCA
CGTGATTAACGGAGCAGCCCAAATTCAAGTCATGTTACATGATGGGCAAAAAGTGACGGCTACGTTGGTTGGAAAGGATG
CCATGACGGATTTAGCGGTGTTAAAGATCGCGGCCGATAAGGTTACCACAACGGCCGCATTTGGTGATTCCAATAAGATC
CAAGTGGGGCAGAAGGTCTTGGCTATTGGCTCACCGTTGGGCGCACAATATGCCTCATCGGTCACAGAGGGAATTATTTC
GGCTAAGAAGCGTTTGGTGGAGTCTTCTTCTGAAGATGGGCAAAATTATGGGGGCTCAACGGTTATTCAAACCGATGCGG
CCATTAACCCTGGTAATTCCGGTGGCCCATTAATCAATTTTGCTGGCCAAGTGATTGGGATTAACTCAATGAAACTCTCT
TCTTCTGCTTCAGGTACGAGTGTTGAAGGGATGGGATTTGCTATTCCGTCAAATCAAGTGGTGGATATTGTTAATAAGTT
GGTCAAGTATGGCCAAGTGACGCGTCCAGCTATTGGTATTGGATTAGTTGAATTATCAGCTGTGACGGTTGATGACCAAA
AGTCACTGTTGAAGATCCCAGATACAGTTAAGGGCGGCGTTGTTGTCATGAGTTTGACCCCTAATGGACCAGCGGCTAAA
GCTGGTATTCAGAAATACGACGTGATTACTGGGATTGATGGCAAAACCGTGACGGGGCAAGCTGACTTGCGTGAAGAATT
ATATAAGCATGATCTTAATGATACGGTCACAATTACTTATTATCACCAAGCAGAGAAAAAGACTGTTAAAGTTAAATTAA
CACAAAAATTAGGAAGTTAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(276-373)

Trypsin-like peptidase domain (Trypsin_2)

(88-234)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mitis NCTC 12261

47.273

100

0.48
  htrA Streptococcus pneumoniae Rx1

46.53

100

0.478
  htrA Streptococcus pneumoniae D39

46.53

100

0.478
  htrA Streptococcus pneumoniae R6

46.53

100

0.478
  htrA Streptococcus pneumoniae TIGR4

46.53

100

0.478
  htrA Streptococcus gordonii str. Challis substr. CH1

47.23

100

0.472
  htrA Streptococcus mutans UA159

49.118

89.71

0.441

Multiple sequence alignment