Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   FGL89_RS05675 Genome accession   NZ_CP042374
Coordinates   1132643..1133782 (+) Length   379 a.a.
NCBI ID   WP_014974933.1    Uniprot ID   K0DBT5
Organism   Leuconostoc carnosum strain CBA3620     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1127643..1138782
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL89_RS05655 (FGL89_05655) yycF 1127759..1128466 (+) 708 WP_014974937.1 response regulator YycF -
  FGL89_RS05660 (FGL89_05660) walK 1128598..1130469 (+) 1872 WP_014974936.1 cell wall metabolism sensor histidine kinase WalK -
  FGL89_RS05665 (FGL89_05665) yycH 1130459..1131763 (+) 1305 WP_014974935.1 two-component system activity regulator YycH -
  FGL89_RS05670 (FGL89_05670) yycI 1131794..1132579 (+) 786 WP_014974934.1 two-component system regulatory protein YycI -
  FGL89_RS05675 (FGL89_05675) htrA 1132643..1133782 (+) 1140 WP_014974933.1 S1C family serine protease Regulator
  FGL89_RS05680 (FGL89_05680) rlmH 1134436..1134915 (+) 480 WP_014974932.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  FGL89_RS05685 (FGL89_05685) thiD 1134993..1135802 (+) 810 WP_014974931.1 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase -
  FGL89_RS05690 (FGL89_05690) - 1135868..1137265 (-) 1398 WP_014974930.1 DHA2 family efflux MFS transporter permease subunit -
  FGL89_RS08640 - 1137405..1137548 (-) 144 WP_014974929.1 hypothetical protein -
  FGL89_RS05695 (FGL89_05695) mutY 1137672..1138694 (+) 1023 WP_014974928.1 A/G-specific adenine glycosylase -

Sequence

Protein


Download         Length: 379 a.a.        Molecular weight: 39605.04 Da        Isoelectric Point: 9.6237

>NTDB_id=377506 FGL89_RS05675 WP_014974933.1 1132643..1133782(+) (htrA) [Leuconostoc carnosum strain CBA3620]
MKQYSLTKIVLTGIIAGVIGGSALLYGQRGVENLQTSTQKVNTKASETSTIPKNATATTAYDKISDAVVSVLNFSQTGQR
RYEESSEGSGVIYKKAGDSAYIVTNNHVISGASKIQVMMHDGKKVEASLVGKDIMTDLAVLKMDAKNVTATASFGDSNKI
QVGQKVLAIGSPLGSQYASSVTQGIISAKKRLVEASSENGQSYGGSTVIQTDAAINPGNSGGPLINFAGQVIGINSMKLS
SSSSGTSVEGMGFAIPSDQVVNIVNELVKNGKITRPAIGISLVELSEITVDDQKALLKIPETVTGGVVVMGTTDNGPAAK
AGLKKYDVITAIEGKTVAGQADLREELYKHKLGDTISVTYYHQATKHTVNIKLTQKLGS

Nucleotide


Download         Length: 1140 bp        

>NTDB_id=377506 FGL89_RS05675 WP_014974933.1 1132643..1133782(+) (htrA) [Leuconostoc carnosum strain CBA3620]
ATGAAACAATATTCATTAACAAAAATCGTATTAACTGGTATCATCGCTGGTGTTATCGGTGGTAGCGCATTATTATATGG
GCAACGTGGTGTTGAAAATTTGCAAACATCGACACAAAAGGTTAACACAAAGGCTAGTGAAACTAGTACTATCCCCAAAA
ACGCTACAGCCACAACGGCTTATGATAAAATCTCTGATGCTGTTGTTTCAGTATTAAATTTTTCACAAACTGGTCAGAGA
CGCTATGAAGAGTCATCTGAAGGTTCTGGTGTGATTTACAAGAAAGCCGGCGATTCAGCCTATATCGTGACCAATAATCA
CGTGATTAGCGGTGCCTCTAAGATTCAAGTAATGATGCATGATGGTAAAAAGGTTGAAGCATCATTAGTCGGCAAAGATA
TCATGACTGATTTAGCTGTTTTAAAAATGGATGCCAAAAATGTGACGGCAACGGCATCATTTGGTGATTCGAATAAAATT
CAAGTTGGGCAAAAGGTGTTAGCTATCGGTTCCCCCTTGGGTTCACAGTACGCTTCTTCAGTGACTCAAGGTATCATTTC
TGCCAAAAAACGTTTAGTTGAGGCGAGCTCTGAAAACGGGCAAAGTTATGGCGGATCAACAGTTATTCAGACAGATGCTG
CTATTAATCCTGGTAATTCAGGTGGACCACTGATTAATTTTGCAGGTCAAGTCATTGGTATTAACTCAATGAAATTATCC
TCCTCCTCATCTGGTACGAGCGTTGAAGGGATGGGATTTGCAATACCTTCAGATCAGGTGGTTAACATTGTCAATGAACT
GGTGAAGAATGGTAAAATCACAAGGCCGGCTATTGGTATTAGCTTAGTCGAACTTTCCGAAATAACGGTTGATGACCAAA
AAGCTTTACTGAAAATTCCAGAAACTGTAACAGGTGGTGTCGTGGTCATGGGCACGACGGATAATGGGCCGGCAGCTAAA
GCTGGTTTGAAGAAGTACGACGTGATTACTGCTATTGAAGGTAAAACAGTGGCTGGTCAAGCAGACTTGCGTGAGGAGCT
CTACAAGCATAAATTAGGAGACACAATCAGCGTAACCTACTATCACCAAGCAACCAAGCACACAGTCAATATTAAATTAA
CACAGAAATTAGGAAGCTAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(276-373)

Trypsin-like peptidase domain (Trypsin_2)

(88-234)

Peptidase family M50 (Peptidase_M50)

(201-375)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB K0DBT5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mitis NCTC 12261

47.044

100

0.483
  htrA Streptococcus mutans UA159

52.059

89.71

0.467
  htrA Streptococcus gordonii str. Challis substr. CH1

46.438

100

0.464
  htrA Streptococcus pneumoniae TIGR4

50.729

90.501

0.459
  htrA Streptococcus pneumoniae D39

50.729

90.501

0.459
  htrA Streptococcus pneumoniae Rx1

50.729

90.501

0.459
  htrA Streptococcus pneumoniae R6

50.729

90.501

0.459

Multiple sequence alignment