Detailed information    

insolico Bioinformatically predicted

Overview


Name   comW   Type   Regulator
Locus tag   HBA50_RS00845 Genome accession   NZ_CP050133
Coordinates   164801..165028 (+) Length   75 a.a.
NCBI ID   WP_045500276.1    Uniprot ID   -
Organism   Streptococcus cristatus ATCC 51100     
Function   stabilization and activation of ComX (predicted from homology)   
Competence regulation

Genomic Context


Location: 159801..170028
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HBA50_RS00825 (HBA50_00825) - 159819..161258 (+) 1440 WP_045500264.1 O-antigen polymerase -
  HBA50_RS00830 (HBA50_00830) - 161265..162338 (+) 1074 WP_045500267.1 polysaccharide pyruvyl transferase family protein -
  HBA50_RS00835 (HBA50_00835) - 162328..163563 (+) 1236 WP_045500270.1 oligosaccharide flippase family protein -
  HBA50_RS00840 (HBA50_00840) wecB 163560..164648 (+) 1089 WP_045500273.1 non-hydrolyzing UDP-N-acetylglucosamine 2-epimerase -
  HBA50_RS00845 (HBA50_00845) comW 164801..165028 (+) 228 WP_045500276.1 sigma(X)-activator ComW Regulator
  HBA50_RS00855 (HBA50_00855) - 165271..166539 (+) 1269 WP_045500279.1 CapA family protein -
  HBA50_RS00860 (HBA50_00860) - 166674..167045 (+) 372 WP_045500282.1 DUF1033 family protein -
  HBA50_RS00865 (HBA50_00865) comGA 167131..168072 (+) 942 WP_045500284.1 competence type IV pilus ATPase ComGA Machinery gene
  HBA50_RS00870 (HBA50_00870) comGB 168020..169036 (+) 1017 WP_045500287.1 competence type IV pilus assembly protein ComGB Machinery gene
  HBA50_RS00875 (HBA50_00875) comGC 169033..169350 (+) 318 WP_045500288.1 competence type IV pilus major pilin ComGC Machinery gene
  HBA50_RS00880 (HBA50_00880) comGD 169310..169744 (+) 435 WP_045500291.1 competence type IV pilus minor pilin ComGD Machinery gene
  HBA50_RS00885 (HBA50_00885) comGE/cglE 169710..170003 (+) 294 WP_200893262.1 competence type IV pilus minor pilin ComGE Machinery gene

Sequence


Protein


Download         Length: 75 a.a.        Molecular weight: 9402.64 Da        Isoelectric Point: 5.5599

>NTDB_id=376859 HBA50_RS00845 WP_045500276.1 164801..165028(+) (comW) [Streptococcus cristatus ATCC 51100]
MEIQEIYNQFRDYYGELEDEYAHCQRTSLEWESLHLRYLIYYLMRYGIGEMKFFNAYHYRAAYRWYLQSLMLGSA

Nucleotide


Download         Length: 228 bp        

>NTDB_id=376859 HBA50_RS00845 WP_045500276.1 164801..165028(+) (comW) [Streptococcus cristatus ATCC 51100]
ATGGAAATTCAAGAAATTTATAATCAATTCAGAGATTACTATGGGGAGCTTGAGGATGAGTATGCTCATTGTCAAAGGAC
GAGTCTGGAGTGGGAAAGCCTGCATTTGCGCTATCTGATTTACTATTTGATGCGCTATGGTATTGGGGAGATGAAGTTTT
TTAATGCCTATCATTATCGGGCAGCTTATCGCTGGTATTTGCAGTCCTTGATGCTGGGCTCTGCCTGA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comW Streptococcus pneumoniae Rx1

45.205

97.333

0.44

  comW Streptococcus pneumoniae D39

45.205

97.333

0.44

  comW Streptococcus pneumoniae R6

45.205

97.333

0.44

  comW Streptococcus pneumoniae TIGR4

45.205

97.333

0.44

  comW Streptococcus mitis NCTC 12261

42.466

97.333

0.413

  comW Streptococcus mitis SK321

42.466

97.333

0.413