Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   HBA50_RS00885 Genome accession   NZ_CP050133
Coordinates   169710..170003 (+) Length   97 a.a.
NCBI ID   WP_200893262.1    Uniprot ID   -
Organism   Streptococcus cristatus ATCC 51100     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 164710..175003
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HBA50_RS00845 (HBA50_00845) comW 164801..165028 (+) 228 WP_045500276.1 sigma(X)-activator ComW Regulator
  HBA50_RS00855 (HBA50_00855) - 165271..166539 (+) 1269 WP_045500279.1 CapA family protein -
  HBA50_RS00860 (HBA50_00860) - 166674..167045 (+) 372 WP_045500282.1 DUF1033 family protein -
  HBA50_RS00865 (HBA50_00865) comGA 167131..168072 (+) 942 WP_045500284.1 competence type IV pilus ATPase ComGA Machinery gene
  HBA50_RS00870 (HBA50_00870) comGB 168020..169036 (+) 1017 WP_045500287.1 competence type IV pilus assembly protein ComGB Machinery gene
  HBA50_RS00875 (HBA50_00875) comGC 169033..169350 (+) 318 WP_045500288.1 competence type IV pilus major pilin ComGC Machinery gene
  HBA50_RS00880 (HBA50_00880) comGD 169310..169744 (+) 435 WP_045500291.1 competence type IV pilus minor pilin ComGD Machinery gene
  HBA50_RS00885 (HBA50_00885) comGE/cglE 169710..170003 (+) 294 WP_200893262.1 competence type IV pilus minor pilin ComGE Machinery gene
  HBA50_RS00890 (HBA50_00890) comGF/cglF 169987..170424 (+) 438 WP_045500297.1 competence type IV pilus minor pilin ComGF Machinery gene
  HBA50_RS00895 (HBA50_00895) comGG 170405..170803 (+) 399 WP_045500299.1 competence type IV pilus minor pilin ComGG Machinery gene
  HBA50_RS00900 (HBA50_00900) comGH 170884..171849 (+) 966 WP_045500301.1 class I SAM-dependent methyltransferase Machinery gene
  HBA50_RS00905 (HBA50_00905) - 171885..173078 (+) 1194 WP_045500304.1 acetate kinase -
  HBA50_RS00910 (HBA50_00910) - 173389..174279 (-) 891 WP_045500311.1 RluA family pseudouridine synthase -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 11098.96 Da        Isoelectric Point: 10.5508

>NTDB_id=376864 HBA50_RS00885 WP_200893262.1 169710..170003(+) (comGE/cglE) [Streptococcus cristatus ATCC 51100]
MESLKRRRMEASILLEALVAMAVFAAIASLLLGQISQSRKEQTRLLQEEEVLRVTRMAMQTGQENLTVNGITVRQTKTDQ
QLTVYHQEEKVLSVKKR

Nucleotide


Download         Length: 294 bp        

>NTDB_id=376864 HBA50_RS00885 WP_200893262.1 169710..170003(+) (comGE/cglE) [Streptococcus cristatus ATCC 51100]
ATGGAAAGTTTAAAAAGACGACGAATGGAGGCTAGTATTTTGCTGGAGGCTCTGGTGGCAATGGCGGTTTTTGCGGCTAT
TGCCAGCCTCCTGCTTGGCCAGATTAGCCAGTCGCGGAAGGAACAGACTCGATTATTGCAGGAGGAGGAAGTCCTACGGG
TTACTCGGATGGCCATGCAGACGGGACAGGAAAATCTGACGGTCAACGGCATCACAGTCCGCCAGACCAAGACCGACCAG
CAATTAACCGTCTACCACCAAGAGGAGAAGGTGCTCAGTGTTAAAAAACGTTAA

Domains

Predicted by InterProScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae Rx1

47.368

97.938

0.464
  comGE/cglE Streptococcus pneumoniae D39

47.368

97.938

0.464
  comGE/cglE Streptococcus pneumoniae R6

47.368

97.938

0.464
  comGE/cglE Streptococcus pneumoniae TIGR4

47.368

97.938

0.464
  comGE/cglE Streptococcus mitis NCTC 12261

46.316

97.938

0.454
  comGE/cglE Streptococcus mitis SK321

46.316

97.938

0.454
  comGE Streptococcus mutans UA140

38.144

100

0.381
  comGE Streptococcus mutans UA159

38.144

100

0.381