Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGD   Type   Machinery gene
Locus tag   G7052_RS03205 Genome accession   NZ_CP049799
Coordinates   640488..640916 (+) Length   142 a.a.
NCBI ID   WP_002986548.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain 1040     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 635488..645916
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  G7052_RS03185 (G7052_03185) - 637819..638184 (+) 366 WP_002986560.1 DUF1033 family protein -
  G7052_RS03190 (G7052_03190) comGA 638277..639215 (+) 939 WP_002986557.1 competence type IV pilus ATPase ComGA Machinery gene
  G7052_RS03195 (G7052_03195) comGB 639151..640185 (+) 1035 WP_011054115.1 competence type IV pilus assembly protein ComGB Machinery gene
  G7052_RS03200 (G7052_03200) comGC 640187..640513 (+) 327 WP_032465607.1 competence type IV pilus major pilin ComGC Machinery gene
  G7052_RS03205 (G7052_03205) comGD 640488..640916 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD Machinery gene
  G7052_RS03210 (G7052_03210) comGE 640873..641157 (+) 285 WP_002987779.1 competence type IV pilus minor pilin ComGE Machinery gene
  G7052_RS03215 (G7052_03215) comGF 641150..641584 (+) 435 WP_023612536.1 competence type IV pilus minor pilin ComGF Machinery gene
  G7052_RS03220 (G7052_03220) comGG 641568..641894 (+) 327 WP_136274078.1 competence type IV pilus minor pilin ComGG -
  G7052_RS03225 (G7052_03225) comGH 641992..642945 (+) 954 WP_136274080.1 class I SAM-dependent methyltransferase Machinery gene
  G7052_RS03230 (G7052_03230) - 643004..644200 (+) 1197 WP_023612537.1 acetate kinase -
  G7052_RS03235 (G7052_03235) - 644387..644695 (+) 309 WP_010921804.1 hypothetical protein -
  G7052_RS03240 (G7052_03240) proC 644778..645548 (-) 771 WP_136274084.1 pyrroline-5-carboxylate reductase -

Sequence

Protein


Download         Length: 142 a.a.        Molecular weight: 16310.04 Da        Isoelectric Point: 10.3481

>NTDB_id=375262 G7052_RS03205 WP_002986548.1 640488..640916(+) (comGD) [Streptococcus pyogenes strain 1040]
MKKPVLAIKAFTLLETLLSLSVMSFIILGLSVPVTKSYQKVEEHLFFSHFEHLYRHQQKLAILQQKQRVLDISSTKIVTE
GNSLTVPKSITVNHPYRLVIDQMGGNHSLAKIIFDMTDRRFKYQFYLGSGNYQKTSQSLHSP

Nucleotide


Download         Length: 429 bp        

>NTDB_id=375262 G7052_RS03205 WP_002986548.1 640488..640916(+) (comGD) [Streptococcus pyogenes strain 1040]
ATGAAAAAGCCCGTCTTAGCAATTAAAGCTTTTACTTTGCTTGAAACTTTACTAAGTTTGTCAGTGATGAGTTTCATTAT
ATTGGGATTGTCTGTACCAGTGACAAAAAGCTATCAAAAAGTAGAAGAGCATCTGTTTTTTAGCCATTTTGAACATTTGT
ATCGACATCAGCAAAAGTTAGCCATATTACAGCAAAAACAGCGCGTCTTGGATATTTCTTCAACAAAAATTGTTACAGAA
GGTAATAGCCTAACAGTTCCTAAATCAATAACAGTGAATCATCCTTATCGGTTAGTTATTGATCAGATGGGAGGCAACCA
TTCCTTAGCTAAAATTATTTTTGACATGACTGATCGACGCTTTAAATACCAATTTTATCTAGGGAGTGGGAATTATCAAA
AAACAAGTCAAAGCTTACATAGCCCTTGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGD Streptococcus mutans UA159

45.736

90.845

0.415
  comGD Streptococcus mutans UA140

45.736

90.845

0.415
  comGD/cglD Streptococcus mitis NCTC 12261

40.441

95.775

0.387
  comGD Streptococcus gordonii str. Challis substr. CH1

40.458

92.254

0.373
  comGD/cglD Streptococcus mitis SK321

39.695

92.254

0.366
  comGD/cglD Streptococcus pneumoniae Rx1

39.695

92.254

0.366
  comGD/cglD Streptococcus pneumoniae D39

39.695

92.254

0.366
  comGD/cglD Streptococcus pneumoniae R6

39.695

92.254

0.366