Detailed information NTG0375210

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: FPT06_RS02380
• Genome accession: NZ_CP041994
• Coordinates: 485195..487432 (-)
• Length: 745 a.a.
• NCBI ID: WP_013730322.1
• Uniprot ID: -
• Organism: Streptococcus suis strain INT-01
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 480195..492432

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FPT06_RS02355 (FPT06_02355)	tmk	480301..480939 (-)	639	WP_002935358.1	dTMP kinase	-
FPT06_RS02360 (FPT06_02360)	-	481114..481980 (+)	867	WP_002935357.1	YitT family protein	-
FPT06_RS02365 (FPT06_02365)	-	482017..483288 (-)	1272	WP_013730324.1	toxic anion resistance protein	-
FPT06_RS02370 (FPT06_02370)	-	483294..484121 (-)	828	WP_002935354.1	hypothetical protein	-
FPT06_RS02375 (FPT06_02375)	-	484215..484871 (-)	657	WP_002935353.1	CBS domain-containing protein	-
FPT06_RS10685	-	485050..485193 (-)	144	WP_002935351.1	transposase	-
FPT06_RS02380 (FPT06_02380)	comEC/celB	485195..487432 (-)	2238	WP_013730322.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
FPT06_RS02385 (FPT06_02385)	-	487416..488078 (-)	663	WP_009909665.1	helix-hairpin-helix domain-containing protein	-
FPT06_RS02390 (FPT06_02390)	-	488146..488892 (-)	747	WP_013730321.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
FPT06_RS02395 (FPT06_02395)	-	489038..490483 (+)	1446	WP_013730320.1	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase	-
FPT06_RS02400 (FPT06_02400)	-	490635..491435 (+)	801	WP_013730319.1	ABC transporter ATP-binding protein	-
FPT06_RS02405 (FPT06_02405)	-	491432..492361 (+)	930	WP_009909659.1	ABC transporter substrate-binding protein	-

Sequence

Protein

• Length: 745 a.a.
• Molecular weight: 84146.89 Da
• Isoelectric Point: 7.3957

>NTDB_id=375210 FPT06_RS02380 WP_013730322.1 485195..487432(-) (comEC/celB) [Streptococcus suis strain INT-01]
MSRLSKLPCQPVHLAVLAVAAYFAVHSFSLLTMGLFSLLLAVFGVRQGKTVFLKTLPLLALCGLFFGYQKVQWERADQSA
TEQVTTVQVIPDTIDINGDSLSFRGRADGQTYQVFYKLTSQEEQTYFQKLTGLVQLEVEAEISLPAGQRNFKGFDYQAYL
KTQGIYRTVKITAIKKIVPVQSWNVFDWLSNWRRQALVYVKTNFPAPMSHYMTGLLFGDLDSDFDQMSDLYSSLGIIHLF
ALSGMQVGFVIDKFRWILLRLGLTKETVDKLQIPFSLVYASLTGFSVSVVRSLVQKILGNLGLRKLDNFAVTVFVCLLIL
PRFLLTAGGVLTFTYAFLLTVFDFEDLGQVKKAAVESLSISLGILPVLMTYFYAFQPLSILLTFAFSFVFDVLLLPGLSV
IFLLSPIVKITWVNGFFVFMEKIIVWVADLGLRPWILGKPSELVLLLLLVSLFLLYDFHRRKKWLLGLSLVLALLFFITK
HPLENEVTVVDIGQGDSIFLRDMRGRTVLIDVGGRVDFAAKEAWQERSRQANAERTLIPYLHSRGVDRIDSLVLTHTDTD
HVGDVLEVAKQVQIGRIYVSPGSLTVPDFVATLKEINVPVHVVEVGERLPIFDSYLEVLYPDGTGDGGNNDSIVLYGRLL
KTNFLFTGDLEQGELDLIESYPNLPVDVLKAGHHGSKGSSYPEFLDHIEAKIALVSAGENNRYKHPHQETLERFDSRNIQ
VYRTDQQGAIRFRGWREWRIETVRR

Nucleotide

• Length: 2238 bp

>NTDB_id=375210 FPT06_RS02380 WP_013730322.1 485195..487432(-) (comEC/celB) [Streptococcus suis strain INT-01]
ATGTCACGGTTGAGTAAGCTCCCCTGCCAGCCCGTTCACCTGGCAGTCTTGGCGGTGGCGGCCTACTTTGCAGTCCATTC
TTTTTCCCTCTTGACAATGGGCCTGTTCAGTCTGTTACTGGCTGTCTTTGGTGTTCGGCAAGGTAAGACGGTTTTCCTCA
AAACGCTGCCGCTTTTAGCTCTATGTGGTCTCTTTTTCGGCTACCAAAAGGTCCAATGGGAGCGGGCAGACCAGTCAGCC
ACAGAGCAAGTCACAACTGTGCAGGTCATTCCAGATACTATTGACATTAACGGGGACAGCCTGTCTTTTCGTGGTCGGGC
TGACGGACAAACCTATCAGGTTTTCTATAAATTAACCAGTCAGGAGGAACAGACCTATTTTCAAAAGCTGACAGGTTTGG
TCCAGCTTGAAGTGGAAGCAGAGATCAGTCTGCCAGCTGGTCAGCGGAATTTCAAGGGTTTTGACTATCAGGCCTACCTG
AAAACACAGGGTATTTATCGGACGGTCAAGATTACGGCAATCAAGAAGATTGTCCCAGTCCAGTCTTGGAATGTCTTTGA
CTGGTTGTCAAACTGGCGGAGGCAGGCTTTGGTTTATGTCAAAACCAATTTTCCGGCTCCCATGAGCCACTACATGACAG
GGCTCTTGTTTGGGGACTTGGATAGTGATTTTGACCAGATGAGTGACCTCTATTCCAGTTTGGGTATCATTCATCTCTTT
GCCCTGTCTGGTATGCAGGTGGGCTTTGTCATCGACAAGTTTCGCTGGATTTTACTGCGTTTGGGCTTGACCAAAGAAAC
GGTTGATAAATTACAAATTCCCTTTTCCCTTGTCTATGCGAGCTTGACAGGTTTTTCCGTATCGGTGGTGCGGTCTTTGG
TTCAAAAAATTTTGGGTAATCTGGGCTTGCGGAAGTTGGATAACTTTGCGGTGACAGTTTTTGTCTGTCTGTTGATACTG
CCCCGATTTCTGCTGACAGCTGGTGGTGTCCTGACCTTTACCTATGCTTTTTTGCTGACGGTTTTTGATTTTGAGGACTT
GGGGCAGGTCAAAAAGGCTGCGGTGGAAAGTCTCAGTATTTCACTTGGGATTTTGCCAGTGCTCATGACCTATTTCTATG
CCTTTCAGCCCCTGTCTATCCTCTTGACCTTTGCCTTTTCTTTTGTCTTTGATGTCCTACTCTTGCCAGGCTTGTCAGTC
ATTTTTCTCCTGTCGCCAATCGTCAAGATTACTTGGGTCAACGGATTTTTTGTCTTTATGGAAAAAATCATTGTCTGGGT
GGCGGATTTGGGATTGCGACCTTGGATACTGGGCAAGCCGTCTGAGCTGGTCCTTTTGCTCTTGCTGGTCAGCCTCTTCT
TACTCTACGATTTCCACAGGAGAAAGAAATGGCTTCTAGGACTGAGCTTGGTCCTCGCTCTGCTATTTTTCATAACCAAA
CACCCGCTGGAAAACGAGGTGACGGTGGTGGACATCGGGCAGGGGGACAGCATCTTTTTGCGGGATATGCGGGGGCGGAC
GGTCCTGATTGATGTGGGCGGACGAGTTGATTTTGCGGCCAAGGAAGCGTGGCAGGAGCGGTCTCGGCAGGCAAATGCAG
AGCGGACTTTGATTCCCTATCTGCATAGTCGGGGTGTGGATAGGATTGATAGTTTAGTCCTGACCCACACCGACACAGAC
CATGTGGGGGATGTGCTGGAAGTGGCGAAGCAGGTCCAGATTGGTCGGATTTACGTGTCGCCGGGAAGCCTGACGGTGCC
TGACTTTGTAGCCACCTTGAAAGAAATTAATGTCCCTGTTCATGTTGTTGAGGTGGGCGAACGCTTACCAATTTTTGACT
CTTACCTGGAAGTCCTTTATCCAGATGGGACAGGAGACGGTGGCAATAATGACTCCATTGTCCTTTATGGTCGCTTGCTG
AAAACTAATTTTCTCTTTACAGGGGACTTGGAGCAGGGGGAGTTGGACTTGATAGAATCTTATCCTAACCTGCCTGTCGA
TGTCCTCAAAGCCGGTCACCACGGCTCCAAAGGTTCTTCCTATCCTGAATTTTTGGACCATATCGAAGCCAAGATTGCCT
TGGTATCTGCTGGAGAAAACAACCGCTACAAGCATCCTCACCAAGAAACCTTGGAACGATTTGATAGTCGCAATATCCAA
GTCTATCGTACAGACCAGCAAGGAGCCATTCGCTTCCGAGGTTGGAGGGAGTGGAGGATTGAAACGGTGAGGAGGTAA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (215-461)

• Metallo-beta-lactamase superfamily (Lactamase_B) (493-698)

• Domain of unknown function (DUF4131) (DUF4131) (29-175)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	53.992	99.195	0.536
comEC/celB	Streptococcus mitis NCTC 12261	52.861	98.523	0.521
comEC/celB	Streptococcus pneumoniae TIGR4	51.973	98.658	0.513
comEC/celB	Streptococcus pneumoniae Rx1	51.701	98.658	0.51
comEC/celB	Streptococcus pneumoniae D39	51.701	98.658	0.51
comEC/celB	Streptococcus pneumoniae R6	51.701	98.658	0.51
comEC	Lactococcus lactis subsp. cremoris KW2	48.865	100	0.491