Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   FPL13_RS06880 Genome accession   NZ_CP041968
Coordinates   1421753..1423621 (-) Length   622 a.a.
NCBI ID   WP_049513530.1    Uniprot ID   A0A7L8W6F9
Organism   Streptococcus sp. KS 6     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1416753..1428621
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FPL13_RS06850 (FPL13_06935) - 1416913..1417230 (+) 318 WP_003043378.1 DUF960 domain-containing protein -
  FPL13_RS06855 (FPL13_06940) - 1417359..1417730 (-) 372 WP_049513538.1 S1 RNA-binding domain-containing protein -
  FPL13_RS06860 (FPL13_06945) - 1417732..1419132 (-) 1401 WP_049513536.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  FPL13_RS06865 (FPL13_06950) - 1419173..1419805 (-) 633 WP_003028406.1 response regulator transcription factor -
  FPL13_RS06870 (FPL13_06955) - 1419807..1420802 (-) 996 WP_049513534.1 sensor histidine kinase -
  FPL13_RS06875 (FPL13_06960) liaF 1420799..1421497 (-) 699 WP_049513532.1 cell wall-active antibiotics response protein LiaF -
  FPL13_RS06880 (FPL13_06965) stkP 1421753..1423621 (-) 1869 WP_049513530.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  FPL13_RS06885 (FPL13_06970) - 1423618..1424358 (-) 741 WP_003025814.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  FPL13_RS06890 (FPL13_06975) rsmB 1424376..1425689 (-) 1314 WP_049513529.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  FPL13_RS06895 (FPL13_06980) fmt 1425679..1426614 (-) 936 WP_049513527.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 622 a.a.        Molecular weight: 67520.56 Da        Isoelectric Point: 9.3344

>NTDB_id=375020 FPL13_RS06880 WP_049513530.1 1421753..1423621(-) (stkP) [Streptococcus sp. KS 6]
MIQVGKIFAGRYRIIKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIG
EEEGQQYLAMEYVAGLDLKRYIKEHAPLSNEEAVRIMGQILLAMRLAHTHGIVHRDLKPQNVLLTPDGDAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSIIAENPNVP
QALENVVIKATAKKLTDRYQSVAEMYVDLSSCLSADRRNEKKLVFDDTAKADTKTLPKVSQNTLTSATKSTPAPTKEVVS
SKPTPKAKKKRRLRTRYKVLLSAVVLVIVALVALVYLSPSNVKIPDVTGKTIAQARSAIETAGLKVGKEKDEYSDSVKKD
SVIRTNPEAGTQRREGSTVDLIVSKGTKTFIMEDYKGQKRADAINNLVQKYKVSKGLIKTEEVESSEYAAGTVVDQTPAA
GSTYDLTSKTRITLKVAKSVSSVTMPSYIGSTYEFAYNNLTEVIGIQGANIEKRTVTTAPASTQANTIIRQTPEAGQSLN
LKSDRIVLYVYEPKTEDSSTSESSSQSDSSSDKTSPSSSSSSASGNDGSSSKTPDTSASASN

Nucleotide


Download         Length: 1869 bp        

>NTDB_id=375020 FPL13_RS06880 WP_049513530.1 1421753..1423621(-) (stkP) [Streptococcus sp. KS 6]
ATGATTCAAGTCGGCAAGATATTTGCCGGACGATATAGAATCATCAAACAAATTGGTCGAGGAGGCATGGCAGATGTCTA
CTTGGCGAAAGACTTGATTTTAGACGGGGAAGAAGTCGCGGTTAAGGTTCTAAGAACCAATTACCAGACAGATCCGATTG
CTGTAGCACGTTTTCAAAGAGAGGCGCGAGCCATGGCAGATTTGGATCATCCTCATATTGTCCGGATTACCGACATTGGA
GAAGAAGAAGGCCAGCAATATCTAGCAATGGAGTATGTGGCTGGACTTGACTTGAAACGCTATATCAAAGAGCATGCTCC
TTTGTCCAATGAAGAAGCGGTGCGAATAATGGGACAAATCCTTTTGGCGATGCGTTTGGCGCACACGCATGGGATTGTTC
ACCGTGATTTGAAACCTCAAAATGTCCTTTTAACTCCAGATGGCGATGCAAAAGTAACGGACTTTGGAATTGCAGTAGCT
TTTGCAGAAACGAGCTTAACGCAAACCAACTCTATGTTGGGATCTGTACATTATCTATCACCAGAACAAGCGCGTGGTTC
AAAAGCGACCGTTCAGAGCGATATTTATGCCATGGGGATTATTTTCTATGAAATGCTGACAGGACATATCCCTTATGATG
GAGATAGTGCTGTTACGATTGCCCTACAACATTTCCAAAAGCCCCTACCGTCCATTATTGCTGAAAATCCAAACGTTCCA
CAAGCATTGGAAAATGTAGTCATCAAGGCAACGGCAAAAAAATTGACGGATCGTTATCAGTCAGTTGCAGAAATGTATGT
GGATTTATCAAGCTGCTTATCTGCTGACCGTCGAAATGAGAAAAAGCTAGTTTTTGATGACACTGCTAAAGCAGACACAA
AGACACTGCCGAAAGTATCACAAAATACCTTGACTTCTGCGACGAAGTCAACACCTGCTCCTACAAAAGAAGTAGTCAGT
AGTAAGCCTACGCCAAAAGCAAAAAAGAAGCGCCGTTTAAGAACACGCTATAAAGTTTTGTTATCAGCGGTGGTTTTAGT
CATCGTAGCTCTGGTGGCTTTAGTCTATTTGAGTCCGTCAAATGTAAAAATCCCAGATGTTACTGGAAAAACTATTGCCC
AAGCACGTTCTGCAATCGAAACTGCAGGTTTGAAAGTTGGCAAGGAAAAAGACGAATACAGTGATTCTGTTAAAAAAGAT
TCAGTTATTCGCACCAATCCAGAAGCGGGAACGCAACGTCGTGAGGGCAGTACGGTGGATCTGATTGTCTCAAAAGGGAC
TAAAACTTTTATTATGGAAGATTATAAAGGTCAGAAAAGAGCAGATGCTATCAACAATCTGGTACAAAAATACAAGGTTT
CAAAAGGCTTAATTAAAACAGAAGAAGTTGAAAGTAGTGAGTATGCGGCAGGAACAGTTGTTGATCAAACACCAGCAGCA
GGCAGCACTTATGATTTGACTTCAAAGACACGTATTACGTTAAAAGTAGCGAAGTCCGTTTCAAGTGTCACGATGCCAAG
CTATATCGGCTCAACCTATGAATTTGCTTATAATAATTTGACGGAAGTGATTGGTATTCAAGGTGCGAATATTGAAAAAC
GTACGGTTACAACAGCTCCAGCGAGTACACAGGCAAATACAATTATCAGACAAACCCCAGAAGCTGGTCAGTCTTTGAAT
TTGAAGAGTGATCGCATTGTCTTATATGTATATGAGCCAAAAACCGAAGATTCTTCAACATCTGAAAGTAGTTCACAATC
TGATAGCAGCTCAGATAAAACCAGCCCATCCTCTAGCAGTTCGTCAGCTAGTGGTAATGATGGAAGCAGTTCAAAAACGC
CAGACACAAGTGCTAGTGCAAGCAATTAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(431-498)

PASTA domain (PASTA)

(503-571)

PASTA domain (PASTA)

(362-425)

Protein kinase domain (Pkinase)

(12-232)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7L8W6F9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

66.038

93.73

0.619
  stkP Streptococcus pneumoniae D39

65.695

93.73

0.616
  stkP Streptococcus pneumoniae R6

65.695

93.73

0.616
  stkP Streptococcus pneumoniae Rx1

65.523

93.73

0.614
  pknB Streptococcus mutans UA159

59.145

94.051

0.556
  stkP/pknB Streptococcus salivarius strain HSISS4

56.492

95.338

0.539

Multiple sequence alignment