Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   FPL13_RS00710 Genome accession   NZ_CP041968
Coordinates   130873..131166 (+) Length   97 a.a.
NCBI ID   WP_049513214.1    Uniprot ID   A0AAU7PY72
Organism   Streptococcus sp. KS 6     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 125873..136166
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FPL13_RS00675 (FPL13_00695) - 125929..126288 (+) 360 WP_049513223.1 MerR family transcriptional regulator -
  FPL13_RS00680 (FPL13_00700) glnA 126326..127672 (+) 1347 WP_049513221.1 type I glutamate--ammonia ligase -
  FPL13_RS00685 (FPL13_00705) - 127860..128225 (+) 366 WP_049507022.1 DUF1033 family protein -
  FPL13_RS00690 (FPL13_00710) comYA 128295..129236 (+) 942 WP_049513218.1 competence type IV pilus ATPase ComGA Machinery gene
  FPL13_RS00695 (FPL13_00715) comGB 129178..130199 (+) 1022 Protein_137 competence type IV pilus assembly protein ComGB -
  FPL13_RS00700 (FPL13_00720) comYC 130196..130513 (+) 318 WP_003028473.1 competence type IV pilus major pilin ComGC Machinery gene
  FPL13_RS00705 (FPL13_00725) comYD 130473..130901 (+) 429 WP_049507639.1 competence type IV pilus minor pilin ComGD Machinery gene
  FPL13_RS00710 (FPL13_00730) comGE/cglE 130873..131166 (+) 294 WP_049513214.1 competence type IV pilus minor pilin ComGE Machinery gene
  FPL13_RS00715 (FPL13_00735) comGF/cglF 131150..131587 (+) 438 WP_049513212.1 competence type IV pilus minor pilin ComGF Machinery gene
  FPL13_RS00720 (FPL13_00740) comGG 131568..131894 (+) 327 WP_264340993.1 competence type IV pilus minor pilin ComGG -
  FPL13_RS00725 (FPL13_00745) - 131966..132918 (+) 953 Protein_143 class I SAM-dependent methyltransferase -
  FPL13_RS00730 (FPL13_00750) - 132965..134164 (+) 1200 WP_049513208.1 acetate kinase -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10895.82 Da        Isoelectric Point: 9.8140

>NTDB_id=374980 FPL13_RS00710 WP_049513214.1 130873..131166(+) (comGE/cglE) [Streptococcus sp. KS 6]
MENLRKQHVKGTILLEALLALAIFATIVTLLLGQIHQSRKAENDLLREEEVLRVAKMALQTKQSHLTMNGIEVRVETSQQ
GIQIYHGKELILGVQGK

Nucleotide


Download         Length: 294 bp        

>NTDB_id=374980 FPL13_RS00710 WP_049513214.1 130873..131166(+) (comGE/cglE) [Streptococcus sp. KS 6]
ATGGAAAATTTAAGAAAACAACACGTTAAAGGAACGATTTTATTAGAGGCGCTGCTTGCGTTAGCTATTTTTGCGACAAT
TGTGACCCTGTTGTTGGGACAAATTCACCAGTCTCGAAAAGCAGAAAATGACTTGCTTAGAGAAGAAGAAGTTTTAAGGG
TAGCTAAAATGGCTTTGCAGACAAAGCAAAGCCATTTGACAATGAACGGTATTGAAGTGCGTGTTGAAACAAGTCAACAA
GGTATTCAAATTTATCATGGGAAGGAGCTGATTCTCGGTGTTCAAGGCAAATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(13-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae Rx1

55.435

94.845

0.526
  comGE/cglE Streptococcus pneumoniae D39

55.435

94.845

0.526
  comGE/cglE Streptococcus pneumoniae R6

55.435

94.845

0.526
  comGE/cglE Streptococcus pneumoniae TIGR4

55.435

94.845

0.526
  comGE/cglE Streptococcus mitis NCTC 12261

54.348

94.845

0.515
  comGE/cglE Streptococcus mitis SK321

54.348

94.845

0.515
  comYE Streptococcus mutans UA140

44.444

100

0.454
  comYE Streptococcus mutans UA159

44.444

100

0.454

Multiple sequence alignment