Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   FLP15_RS10965 Genome accession   NZ_CP041356
Coordinates   2295009..2295701 (-) Length   230 a.a.
NCBI ID   WP_120772040.1    Uniprot ID   A0A514ZAI2
Organism   Lactococcus protaetiae strain KACC 19320     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 2290009..2300701
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FLP15_RS10950 (FLP15_10950) - 2290489..2290830 (-) 342 WP_142767146.1 P-II family nitrogen regulator -
  FLP15_RS10955 (FLP15_10955) - 2291433..2292674 (-) 1242 WP_142767503.1 ammonium transporter -
  FLP15_RS10960 (FLP15_10960) covS 2293522..2295000 (-) 1479 WP_142767147.1 HAMP domain-containing histidine kinase Regulator
  FLP15_RS10965 (FLP15_10965) covR 2295009..2295701 (-) 693 WP_120772040.1 response regulator transcription factor Regulator
  FLP15_RS10970 (FLP15_10970) - 2295856..2296386 (-) 531 WP_142767504.1 DUF177 domain-containing protein -
  FLP15_RS10975 (FLP15_10975) - 2296924..2297169 (-) 246 WP_120772041.1 type B 50S ribosomal protein L31 -
  FLP15_RS10980 (FLP15_10980) - 2297332..2298411 (-) 1080 WP_142767505.1 carbamoyl phosphate synthase small subunit -
  FLP15_RS10985 (FLP15_10985) - 2299348..2300259 (-) 912 Protein_2199 aspartate carbamoyltransferase catalytic subunit -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26721.42 Da        Isoelectric Point: 5.1218

>NTDB_id=371503 FLP15_RS10965 WP_120772040.1 2295009..2295701(-) (covR) [Lactococcus protaetiae strain KACC 19320]
MTSKKILIIEDEKNLARFVSLELEHEGYSTEIKDNGRSGLEEALAKDYDLLLLDLMLPELDGFEVARRLRKEKDTPIIMM
TARDSTMDRVAGLDIGADDYITKPFAIEELLARVRAFFRREDHAHAVEQSENTTFRDLVIDKTNRTVHRGKKVIDLTRRE
YDLLLTLMQNVGDVVTREHLVSQVWGYEEGTETNVVDVYIRYLRNKIDVEGHESYIQTVRGLGYVMRERK

Nucleotide


Download         Length: 693 bp        

>NTDB_id=371503 FLP15_RS10965 WP_120772040.1 2295009..2295701(-) (covR) [Lactococcus protaetiae strain KACC 19320]
ATGACATCGAAAAAAATATTGATTATAGAGGATGAAAAAAATTTAGCACGCTTTGTTTCACTTGAATTGGAACATGAGGG
ATATTCAACAGAGATTAAAGACAATGGTCGTTCAGGTCTTGAAGAAGCTCTAGCAAAAGATTACGATTTACTTTTGTTGG
ACTTGATGTTGCCAGAACTTGATGGTTTCGAGGTGGCTCGTCGTTTGCGTAAAGAAAAAGACACACCGATTATCATGATG
ACGGCACGTGATTCTACAATGGACCGAGTGGCCGGTCTTGATATTGGTGCAGATGACTACATTACTAAACCATTTGCTAT
TGAAGAGCTATTGGCGCGTGTTCGTGCATTCTTCCGTCGTGAAGATCATGCTCATGCGGTAGAACAATCAGAAAATACGA
CTTTCAGAGATTTAGTGATTGATAAAACAAATCGTACAGTGCATCGTGGTAAAAAGGTTATTGACCTTACTCGCCGTGAA
TACGACTTGCTTTTGACTTTGATGCAAAATGTTGGTGATGTTGTGACTCGTGAACATTTAGTGTCACAAGTTTGGGGATA
TGAAGAAGGAACAGAAACAAATGTTGTTGATGTCTATATTCGTTATCTTCGCAACAAAATTGATGTTGAAGGACATGAAA
GCTATATTCAAACGGTACGTGGTTTGGGATACGTGATGCGTGAACGTAAGTAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-226)

Response regulator receiver domain (Response_reg)

(6-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A514ZAI2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Lactococcus lactis subsp. lactis strain DGCC12653

95.217

100

0.952
  covR Streptococcus salivarius strain HSISS4

69.298

99.13

0.687
  vicR Streptococcus mutans UA159

44.589

100

0.448
  micA Streptococcus pneumoniae Cp1015

43.913

100

0.439

Multiple sequence alignment