Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   FLP15_RS01320 Genome accession   NZ_CP041356
Coordinates   274895..276118 (+) Length   407 a.a.
NCBI ID   WP_142765703.1    Uniprot ID   A0A514Z640
Organism   Lactococcus protaetiae strain KACC 19320     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 269895..281118
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FLP15_RS01295 (FLP15_01295) - 270684..271418 (-) 735 WP_142767400.1 DNA alkylation repair protein -
  FLP15_RS01300 (FLP15_01300) - 271418..271810 (-) 393 WP_142765699.1 tautomerase family protein -
  FLP15_RS01305 (FLP15_01305) - 272344..273093 (-) 750 WP_142765700.1 ABC transporter permease -
  FLP15_RS01310 (FLP15_01310) - 273102..273965 (-) 864 WP_142765701.1 ABC transporter ATP-binding protein -
  FLP15_RS01315 (FLP15_01315) rlmH 274055..274534 (-) 480 WP_142765702.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  FLP15_RS01320 (FLP15_01320) htrA 274895..276118 (+) 1224 WP_142765703.1 trypsin-like peptidase domain-containing protein Regulator
  FLP15_RS01325 (FLP15_01325) - 276242..277239 (+) 998 Protein_260 glycosyltransferase -
  FLP15_RS01330 (FLP15_01330) - 277802..279142 (+) 1341 WP_142765704.1 glycosyltransferase family 4 protein -
  FLP15_RS01335 (FLP15_01335) - 279297..279520 (+) 224 Protein_262 DUF1797 family protein -
  FLP15_RS12905 - 279752..280069 (+) 318 WP_223804676.1 hypothetical protein -
  FLP15_RS01340 (FLP15_01340) - 280078..280755 (+) 678 WP_223804677.1 hypothetical protein -

Sequence

Protein


Download         Length: 407 a.a.        Molecular weight: 41826.39 Da        Isoelectric Point: 4.6071

>NTDB_id=371484 FLP15_RS01320 WP_142765703.1 274895..276118(+) (htrA) [Lactococcus protaetiae strain KACC 19320]
MSKGNFGKMLLTGVVGGAIALGGSAIYQNATNNNTASTSGSSVPVKTVKVDVNTDTTAAIKKVSNAVVSVLNYQNQSSSD
DVFNSIFGQNSGNNQSSATSSLASEGSGVIYKKENGKAYIVTNNHVVEGANSLEVLLAGGQKVKATLVGTDAYTDLAVLK
IDDSDVKEVATFADSSNLTIGEPAIAVGSPLGSEFANTATEGIVSAINRQVSMQNDEGQNVNVNAIQTDAAINPGNSGGA
LINIEGQVIGITQSKLTTTQDGSTSVEGMGFAIPSNDVVNIIAKLEKDGKVIRPALGITMVDLSQFSTDDLNQLKLPDSV
TGGVVVHTVQSGMPASTAGLKAGDVITKIGDTTITSSTDLQSALYKYNIGDTVAITYYRDGKSHTANVKLNKSTSDLQQS
SSSSQNP

Nucleotide


Download         Length: 1224 bp        

>NTDB_id=371484 FLP15_RS01320 WP_142765703.1 274895..276118(+) (htrA) [Lactococcus protaetiae strain KACC 19320]
ATGTCAAAAGGTAATTTCGGGAAAATGCTCTTGACTGGTGTCGTAGGTGGGGCCATCGCACTAGGCGGGAGTGCAATTTA
CCAAAACGCAACAAACAATAATACCGCTAGTACTAGTGGTTCCTCCGTTCCAGTCAAGACTGTAAAAGTTGATGTTAATA
CAGACACAACTGCTGCAATCAAAAAGGTTTCTAACGCAGTTGTTTCCGTCCTTAACTATCAAAATCAGAGTTCCAGTGAC
GATGTTTTCAACAGTATCTTCGGACAAAATAGTGGAAACAACCAAAGTTCAGCAACTTCTAGTTTAGCTAGTGAAGGTTC
TGGAGTCATTTATAAAAAAGAGAACGGTAAAGCTTATATCGTTACTAACAATCACGTTGTAGAAGGTGCTAATAGCCTCG
AAGTCCTGTTAGCTGGTGGTCAAAAAGTAAAAGCTACTCTAGTTGGCACAGATGCTTACACTGACCTTGCCGTACTTAAA
ATTGATGATAGTGACGTTAAAGAAGTAGCTACTTTCGCAGATTCTAGTAACTTAACAATTGGAGAACCTGCAATTGCAGT
CGGCTCTCCTCTCGGTTCTGAGTTTGCTAATACCGCAACAGAAGGAATTGTTTCAGCCATTAATCGTCAAGTATCAATGC
AGAATGATGAAGGACAAAATGTCAATGTCAATGCAATTCAAACTGATGCTGCCATCAATCCAGGAAATTCTGGAGGAGCA
TTAATTAATATTGAAGGACAAGTCATTGGTATTACACAGTCAAAACTGACAACTACCCAAGATGGCTCAACAAGCGTTGA
AGGAATGGGATTTGCCATTCCATCCAATGATGTGGTTAACATTATTGCTAAACTTGAAAAAGACGGTAAAGTTATTCGTC
CTGCATTAGGTATTACGATGGTTGATTTGTCACAATTCTCAACTGATGACCTCAATCAGCTCAAACTTCCTGATAGTGTA
ACTGGTGGTGTGGTTGTTCATACTGTTCAATCAGGTATGCCTGCTAGTACTGCTGGTCTAAAAGCTGGAGATGTCATCAC
AAAGATTGGTGATACAACAATTACCTCTTCAACAGATTTGCAAAGTGCTCTTTATAAATATAATATTGGAGATACTGTCG
CTATTACCTATTACCGTGATGGTAAATCTCACACAGCCAATGTTAAACTCAATAAATCAACAAGTGACTTGCAACAATCA
AGCTCATCAAGCCAAAACCCTTAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(294-390)

Trypsin-like peptidase domain (Trypsin_2)

(106-251)

Peptidase family M50 (Peptidase_M50)

(266-395)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A514Z640

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus gordonii str. Challis substr. CH1

54.337

96.314

0.523
  htrA Streptococcus mitis NCTC 12261

54.617

93.12

0.509
  htrA Streptococcus pneumoniae Rx1

57.726

84.275

0.486
  htrA Streptococcus pneumoniae D39

57.726

84.275

0.486
  htrA Streptococcus pneumoniae R6

57.726

84.275

0.486
  htrA Streptococcus pneumoniae TIGR4

57.726

84.275

0.486
  htrA Streptococcus mutans UA159

49.373

98.034

0.484

Multiple sequence alignment