Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   FEE39_RS02565 Genome accession   NZ_CP040854
Coordinates   546501..548660 (+) Length   719 a.a.
NCBI ID   WP_023599382.1    Uniprot ID   A0A7D9N5H0
Organism   Lactobacillus johnsonii strain G2A     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 541501..553660
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FEE39_RS02535 (FEE39_02575) - 541529..541681 (+) 153 WP_023599380.1 hypothetical protein -
  FEE39_RS02540 (FEE39_02580) - 541672..541905 (+) 234 WP_239499852.1 hypothetical protein -
  FEE39_RS02545 (FEE39_02585) - 541902..542951 (-) 1050 Protein_501 IS30-like element ISLjo1 family transposase -
  FEE39_RS02550 (FEE39_02590) - 543105..544193 (+) 1089 WP_239499853.1 GHKL domain-containing protein -
  FEE39_RS02555 (FEE39_02595) - 544336..545493 (+) 1158 WP_011161707.1 RNA-guided endonuclease TnpB family protein -
  FEE39_RS02560 (FEE39_02600) - 545691..546488 (+) 798 WP_011161708.1 LytTR family DNA-binding domain-containing protein -
  FEE39_RS02565 (FEE39_02605) comA 546501..548660 (+) 2160 WP_023599382.1 peptide cleavage/export ABC transporter Regulator
  FEE39_RS02570 (FEE39_02610) - 548671..549264 (+) 594 WP_011161710.1 HlyD family efflux transporter periplasmic adaptor subunit -
  FEE39_RS02575 (FEE39_02615) - 549391..549618 (+) 228 WP_014567249.1 bacteriocin class II family protein -
  FEE39_RS02580 (FEE39_02620) - 549629..549817 (+) 189 WP_011161712.1 Blp family class II bacteriocin -
  FEE39_RS02585 (FEE39_02625) - 549904..550278 (+) 375 WP_011161713.1 hypothetical protein -
  FEE39_RS10855 - 550429..550554 (+) 126 WP_023599383.1 hypothetical protein -
  FEE39_RS02590 (FEE39_02635) - 550638..551687 (+) 1050 WP_163588710.1 IS30-like element ISLjo1 family transposase -
  FEE39_RS02595 (FEE39_02640) - 551719..551955 (+) 237 Protein_512 peptide ABC transporter ATP-binding protein -
  FEE39_RS10920 (FEE39_02645) - 551966..552590 (+) 625 Protein_513 hypothetical protein -
  FEE39_RS02605 (FEE39_02650) - 552740..552934 (+) 195 WP_011161718.1 hypothetical protein -
  FEE39_RS02610 (FEE39_02655) - 553047..553337 (+) 291 WP_011161719.1 bacteriocin immunity protein -

Sequence

Protein


Download         Length: 719 a.a.        Molecular weight: 81150.57 Da        Isoelectric Point: 7.9626

>NTDB_id=367648 FEE39_RS02565 WP_023599382.1 546501..548660(+) (comA) [Lactobacillus johnsonii strain G2A]
MLFKYKSVYVPQVDEMDCGVACLAMILKQYHSRISLAHLRHEARTNLEGTTALGLVKTAQKFNLKTEAVKADMSLFNDDG
IQYPFIAHVLKQGELLHYYVVLKNTKNYLLIADPDPSVGVIKMPKDRFAQEWTGIALFMVPNENFEPIKEKKNNLWSLFP
YMFKQKRLMINIILAALLMTIISICSSYFVQGIIDTYIPSGTYQTLSILAVGLLIAYVFNSIFSYGQNFLLNVLGQRLSI
DLNLQYIRHIFELPMEFFVTRRTGEITSRFSDASRIIDALASTVISLFLDLSIVIVMGLVLAAQSMTLFGITLLALPIYA
VVILGFTKKFEKLNNEQMESNAVLSSSVIEDIQGIETIKALNSENTRYRRIDSQFVDYLKKSFKYSKTESLQTALKTFIQ
LSLNVIILWVGAKVVMQGQLSIGQLMTFNALLAYFIDPLQNIINLQPRLQSASVAKNRLNEVYQVKSEFNQKTAIEDCKL
LEGNIEYKNVDYRYGYGADVLKDINLKINQGEKLTIVGMSGSGKSTMVKLLVDFFSPSKGQVILNGHATSEINKHSLRSY
VNYVPQTPYIFSGTVRENLLLGCRPDITEEDVIEACQIAEIDQEIANLPLQFETKLDENAKILSGGQKQRLTIARALLSP
AKVFIFDEVTSGLDTITEKRVIDNLMKLKDKTIIFIAHRLAIAERADKVVVIDRGQIVEEGSHSELMNMHGFYYDLVKG

Nucleotide


Download         Length: 2160 bp        

>NTDB_id=367648 FEE39_RS02565 WP_023599382.1 546501..548660(+) (comA) [Lactobacillus johnsonii strain G2A]
ATGTTATTCAAATATAAATCTGTTTATGTACCTCAAGTAGATGAGATGGATTGCGGAGTTGCTTGTTTAGCGATGATCTT
AAAACAATATCATTCTCGTATATCTTTAGCTCATTTACGTCATGAAGCGCGTACTAATCTTGAAGGAACAACTGCTTTAG
GGTTAGTTAAAACAGCCCAGAAATTTAATTTAAAAACAGAAGCCGTAAAGGCAGATATGTCTTTATTTAATGATGACGGT
ATTCAGTATCCTTTTATTGCTCACGTACTTAAACAGGGAGAATTGCTTCACTATTATGTGGTGCTAAAAAATACTAAAAA
TTATTTATTAATTGCCGATCCAGATCCTTCAGTTGGTGTGATAAAAATGCCTAAAGATAGGTTCGCTCAAGAATGGACAG
GGATTGCACTCTTTATGGTTCCCAATGAAAACTTTGAACCAATTAAAGAAAAGAAGAATAACCTATGGTCTCTCTTTCCA
TATATGTTTAAACAAAAGCGGCTAATGATTAATATCATTCTAGCCGCTTTATTAATGACCATAATTAGTATCTGTAGTTC
ATATTTTGTTCAAGGAATAATTGATACTTATATTCCAAGTGGTACTTATCAGACTTTATCAATCTTAGCAGTCGGATTGT
TAATTGCTTATGTCTTTAATTCTATCTTCTCCTATGGACAGAATTTTTTGCTAAATGTTTTAGGACAAAGATTAAGTATT
GATTTAAATCTTCAATATATTAGACATATTTTTGAATTACCGATGGAATTTTTTGTAACAAGAAGAACGGGTGAAATTAC
TTCACGTTTTTCTGATGCAAGTAGAATTATTGATGCTTTGGCAAGTACGGTTATCTCGCTTTTCTTAGATCTATCAATTG
TAATCGTAATGGGATTAGTATTAGCGGCTCAGAGTATGACTTTGTTTGGAATCACATTATTGGCTTTACCTATTTATGCA
GTTGTAATTCTAGGTTTTACTAAAAAGTTTGAAAAATTAAATAATGAGCAAATGGAAAGTAATGCTGTTTTGAGTTCTTC
AGTTATTGAAGACATTCAAGGAATTGAAACAATTAAAGCATTAAATAGTGAGAATACAAGGTATAGAAGAATCGATAGTC
AGTTTGTAGATTACTTAAAAAAATCTTTTAAATACAGCAAAACTGAGAGCTTGCAGACAGCACTCAAGACATTTATTCAA
TTATCTCTTAATGTAATTATTCTTTGGGTTGGTGCAAAAGTTGTAATGCAAGGACAATTGAGCATTGGTCAGTTGATGAC
TTTTAATGCGTTGCTGGCATATTTTATTGATCCACTGCAAAATATTATTAATCTGCAACCGCGACTTCAATCAGCTAGTG
TTGCTAAAAATCGATTGAATGAGGTCTATCAAGTAAAAAGTGAATTCAATCAGAAGACTGCTATTGAAGATTGTAAGCTC
CTAGAAGGAAATATTGAATATAAGAATGTGGATTATCGCTATGGTTATGGTGCAGATGTCTTAAAAGATATTAATCTAAA
AATTAACCAGGGCGAAAAATTAACGATTGTTGGAATGAGTGGATCTGGAAAATCAACAATGGTTAAGTTGTTAGTAGATT
TCTTTTCGCCAAGTAAGGGTCAAGTCATTTTAAATGGCCATGCAACAAGTGAGATTAATAAGCATAGCTTGCGATCATAT
GTGAATTATGTACCTCAAACCCCATATATCTTTTCTGGAACAGTTAGAGAGAATTTGTTGTTAGGTTGTAGGCCAGATAT
CACTGAAGAAGATGTAATAGAGGCTTGTCAGATTGCTGAGATTGACCAAGAAATAGCTAATCTACCTTTGCAATTTGAAA
CAAAATTAGATGAAAATGCAAAAATTCTATCTGGTGGACAAAAACAAAGGTTAACAATTGCTCGGGCATTATTATCTCCT
GCAAAGGTATTTATCTTTGATGAAGTAACAAGTGGCTTAGATACAATTACTGAGAAGAGAGTAATTGATAATTTGATGAA
GCTCAAAGATAAGACAATTATTTTTATCGCACACCGTCTGGCAATTGCGGAACGAGCAGATAAGGTTGTTGTAATTGATC
GTGGCCAGATAGTTGAAGAAGGCAGTCACAGCGAATTGATGAATATGCATGGCTTTTATTATGACTTAGTGAAGGGATAG

Domains

Predicted by InterproScan.

Peptidase C39 family (Peptidase_C39)

(7-143)

ABC transporter transmembrane region (ABC_membrane)

(169-439)

ABC transporter (ABC_tran)

(501-651)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7D9N5H0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis NCTC 12261

57.303

99.026

0.567
  comA Streptococcus mitis SK321

57.022

99.026

0.565
  comA Streptococcus pneumoniae Rx1

56.882

99.026

0.563
  comA Streptococcus pneumoniae D39

56.882

99.026

0.563
  comA Streptococcus pneumoniae R6

56.882

99.026

0.563
  comA Streptococcus pneumoniae TIGR4

56.742

99.026

0.562
  comA Streptococcus gordonii str. Challis substr. CH1

55.758

99.026

0.552
  comA/nlmT Streptococcus mutans UA159

53.324

98.331

0.524

Multiple sequence alignment