Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   FHI56_RS11300 Genome accession   NZ_CP040804
Coordinates   2192294..2193043 (-) Length   249 a.a.
NCBI ID   WP_149561500.1    Uniprot ID   A0AB37CNP9
Organism   Streptococcus salivarius strain LAB813     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 2187294..2198043
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FHI56_RS11280 (FHI56_11280) - 2187616..2188848 (-) 1233 WP_149561499.1 cysteine desulfurase -
  FHI56_RS11285 (FHI56_11285) sufD 2188902..2190164 (-) 1263 WP_002886437.1 Fe-S cluster assembly protein SufD -
  FHI56_RS11290 (FHI56_11290) sufC 2190201..2190971 (-) 771 WP_002883600.1 Fe-S cluster assembly ATPase SufC -
  FHI56_RS11295 (FHI56_11295) - 2191133..2192290 (-) 1158 WP_014633670.1 glycosyltransferase family 4 protein -
  FHI56_RS11300 (FHI56_11300) mecA 2192294..2193043 (-) 750 WP_149561500.1 adaptor protein MecA Regulator
  FHI56_RS11305 (FHI56_11305) - 2193250..2193621 (+) 372 WP_149561501.1 DUF3021 family protein -
  FHI56_RS11310 (FHI56_11310) - 2193681..2194535 (-) 855 WP_002883622.1 undecaprenyl-diphosphate phosphatase -
  FHI56_RS11315 (FHI56_11315) - 2194741..2196288 (+) 1548 WP_149561502.1 ABC transporter substrate-binding protein/permease -
  FHI56_RS11320 (FHI56_11320) - 2196288..2197028 (+) 741 WP_013989971.1 amino acid ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 249 a.a.        Molecular weight: 29071.68 Da        Isoelectric Point: 4.0148

>NTDB_id=367388 FHI56_RS11300 WP_149561500.1 2192294..2193043(-) (mecA) [Streptococcus salivarius strain LAB813]
MEMKQISETTLKIMITMEDLEEHGMELKDFLIPQEKTEEFFYTVMDELDLPDNFKNSGMLSFRVTPRKDRVDVFVTKSDL
KEDLDFNDLSDMDDYSGLSPEEFLKALEGNFMDKGDIEAHHKLEELEKTLEEVDKAMTEPTKEVAEEIIREDYTHYVLAF
SDFDQVVTFTQGLKDVPVEGSELYKLGDVYYMTILLYLADEPDYYANNMYARFLEYANVADRTRAYLQEHATILMEDDAL
PVLQATKWS

Nucleotide


Download         Length: 750 bp        

>NTDB_id=367388 FHI56_RS11300 WP_149561500.1 2192294..2193043(-) (mecA) [Streptococcus salivarius strain LAB813]
ATGGAAATGAAACAAATAAGCGAGACAACTCTAAAAATCATGATTACCATGGAAGATCTTGAAGAACATGGTATGGAATT
GAAAGATTTCTTGATTCCCCAGGAAAAAACAGAGGAATTTTTCTATACTGTCATGGATGAGTTGGACTTGCCTGATAACT
TTAAAAATAGTGGGATGCTGAGCTTCCGTGTCACGCCACGCAAGGATCGTGTGGATGTCTTTGTTACTAAATCAGATCTT
AAGGAAGACCTTGATTTCAATGATTTGTCAGATATGGATGACTACTCAGGGCTTTCTCCAGAAGAGTTCCTAAAGGCCCT
TGAGGGTAATTTTATGGACAAGGGTGACATCGAAGCACACCATAAGCTCGAAGAGCTTGAAAAGACCTTGGAAGAGGTTG
ATAAGGCTATGACAGAGCCTACCAAGGAAGTGGCTGAAGAAATTATTCGTGAAGACTATACCCACTATGTCTTGGCTTTC
TCTGACTTTGATCAAGTGGTGACCTTTACACAAGGTTTGAAAGATGTACCTGTTGAAGGTTCTGAGCTTTATAAACTTGG
GGACGTCTACTACATGACGATCCTTCTTTACTTGGCTGATGAGCCTGATTATTACGCGAACAATATGTATGCGCGTTTTC
TCGAATATGCGAATGTGGCAGACCGAACACGTGCCTACCTACAAGAGCATGCAACAATCTTGATGGAAGATGATGCTTTA
CCGGTACTACAAGCAACGAAATGGAGCTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus thermophilus LMD-9

93.976

100

0.94
  mecA Streptococcus thermophilus LMG 18311

93.173

100

0.932
  mecA Streptococcus mutans UA159

60.246

97.992

0.59
  mecA Streptococcus pneumoniae Rx1

47.39

100

0.474
  mecA Streptococcus pneumoniae D39

47.39

100

0.474
  mecA Streptococcus pneumoniae R6

47.39

100

0.474
  mecA Streptococcus pneumoniae TIGR4

47.39

100

0.474

Multiple sequence alignment