Detailed information NTG0367380

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: FHI56_RS10755
• Genome accession: NZ_CP040804
• Coordinates: 2081684..2083780 (-)
• Length: 698 a.a.
• NCBI ID: WP_149561488.1
• Uniprot ID: A0AB37CR38
• Organism: Streptococcus salivarius strain LAB813
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 2076684..2088780

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FHI56_RS10720 (FHI56_10720)	ureE	2076891..2077343 (-)	453	WP_002949549.1	urease accessory protein UreE	-
FHI56_RS10725 (FHI56_10725)	ureC	2077484..2079202 (-)	1719	WP_149561487.1	urease subunit alpha	-
FHI56_RS10730 (FHI56_10730)	-	2079218..2079529 (-)	312	WP_002886559.1	urease subunit beta	-
FHI56_RS10735 (FHI56_10735)	-	2079541..2079843 (-)	303	WP_002886558.1	urease subunit gamma	-
FHI56_RS10740 (FHI56_10740)	-	2079868..2080383 (-)	516	WP_002886548.1	AmiS/UreI family transporter	-
FHI56_RS12115	-	2080771..2081190 (+)	420	WP_229058093.1	hypothetical protein	-
FHI56_RS10750 (FHI56_10750)	-	2081242..2081574 (-)	333	WP_013990041.1	DUF805 domain-containing protein	-
FHI56_RS10755 (FHI56_10755)	comA	2081684..2083780 (-)	2097	WP_149561488.1	peptide cleavage/export ABC transporter	Regulator
FHI56_RS10760 (FHI56_10760)	comR	2083955..2084854 (-)	900	WP_070579027.1	helix-turn-helix transcriptional regulator	Regulator
FHI56_RS10765 (FHI56_10765)	-	2085034..2085684 (-)	651	WP_045001950.1	phosphatase PAP2 family protein	-
FHI56_RS10770 (FHI56_10770)	-	2085687..2086244 (-)	558	WP_118185136.1	ECF transporter S component	-
FHI56_RS10775 (FHI56_10775)	-	2086553..2087062 (-)	510	WP_049529100.1	tRNA (cytidine(34)-2'-O)-methyltransferase	-
FHI56_RS10780 (FHI56_10780)	trkA	2087340..2088689 (+)	1350	WP_013990035.1	Trk system potassium transporter TrkA	-

Sequence

Protein

• Length: 698 a.a.
• Molecular weight: 78490.39 Da
• Isoelectric Point: 9.1772

>NTDB_id=367380 FHI56_RS10755 WP_149561488.1 2081684..2083780(-) (comA) [Streptococcus salivarius strain LAB813]
MSKYPYISQVDQRDCGVAALAMILKHYGSSYSLAYLRELAQTSREGTSALGLVKAAKQLGLETQAIRADLDLFKQESLSY
PFIAHVVKEGGLQHYYTVFGQIKGKLVIGDPDPSKKVIKMPLEEFAKEWTGVALFFVPGETYTKYKEDVPGLLSFLPILF
RRKGLIAVIVLLSFLVTLVNIIGSYYLQSIIDRLIPQEAYTLLTMISLGLCISYLAQQVFTFFKDYLLHRLGNYLSIAVI
LPYIKHVFSLPISFFSSRRTGEITSRFGDANTIIDALASTILSIFLDVTIVMTLAVALILQNQSLFVMTLTVVPLYVLII
LAFYKLFEKENYQLMEANSQVNTAVIDDLRGIETLKSLRVEERRYQEIEVKFHDYLKKSLSKAKWQLTQDGLKTGVQLVS
NVFILWYGAQLVMEGQLSAGQLITYNMLLNYFTTPLINIINLQSKIQQAKVANNRLQEVYVVDKEEEGKLKELSFKQLAL
KGVSHRFSYQQETLSKIDLTIHKGEKIALMGKSGSGKTTLAKMLSGYYTKSSGHVTLDKDAISHAELRQMVTYVPQQTYV
FTGTILENLLLGYEGEVDEKKLLKVCQQADILEDIQKMPQGFQTQVSEDGGLSGGQKQRLAVARALLSKQPILVFDEATS
GLDSDTESRVMANLAKIKRTMIFIAHRNSVRQHVSRVVTMVSGQIESDSPNFNPFQFI

Nucleotide

• Length: 2097 bp

>NTDB_id=367380 FHI56_RS10755 WP_149561488.1 2081684..2083780(-) (comA) [Streptococcus salivarius strain LAB813]
ATGTCAAAATATCCATATATTTCACAGGTTGATCAGCGTGATTGTGGTGTCGCTGCCTTGGCCATGATTCTTAAACACTA
TGGTTCATCTTATAGTTTAGCTTATTTGCGGGAGTTGGCTCAGACTTCTCGTGAAGGCACTTCTGCGCTTGGTTTGGTTA
AAGCGGCCAAGCAGTTGGGCCTTGAAACTCAGGCTATTCGTGCGGATTTAGACTTGTTTAAACAAGAAAGCCTATCTTAT
CCTTTTATTGCACATGTGGTTAAAGAAGGTGGATTGCAACATTATTATACGGTGTTTGGTCAAATCAAGGGGAAGCTTGT
TATTGGTGATCCAGATCCTAGCAAGAAGGTCATTAAAATGCCCTTAGAGGAGTTTGCCAAAGAGTGGACGGGAGTTGCTC
TCTTTTTTGTTCCAGGAGAAACTTACACTAAATACAAAGAAGATGTGCCTGGGCTTCTTTCATTTTTACCAATTTTGTTT
CGTCGTAAGGGTTTGATTGCAGTTATTGTCTTGTTAAGTTTTCTAGTGACCCTTGTTAATATTATTGGTTCTTATTATTT
GCAATCTATTATTGACCGCTTGATTCCTCAGGAGGCCTACACTCTTCTAACCATGATTTCGCTAGGCCTATGTATCTCTT
ATCTAGCTCAACAAGTATTTACTTTTTTCAAAGATTATCTTCTACATCGATTGGGGAATTACTTGTCCATTGCTGTCATT
CTTCCTTATATTAAGCATGTCTTTTCCTTACCTATTAGTTTCTTTAGTTCACGTCGTACTGGTGAAATAACGTCACGTTT
TGGCGATGCTAACACTATTATCGATGCTCTAGCTTCAACGATTTTATCGATTTTCCTAGATGTGACCATTGTGATGACTC
TAGCTGTGGCTCTTATTTTACAAAATCAGTCACTTTTTGTGATGACTCTCACGGTAGTGCCTCTTTATGTTTTAATCATT
TTGGCCTTCTATAAGCTTTTTGAAAAGGAAAATTATCAATTGATGGAGGCAAATAGTCAGGTCAATACCGCTGTTATTGA
TGATTTGCGAGGCATTGAAACCTTAAAATCCTTGAGAGTTGAAGAGAGACGCTATCAGGAAATTGAGGTGAAATTCCATG
ACTATTTGAAGAAGTCTTTGTCTAAGGCCAAGTGGCAATTAACGCAAGATGGTTTAAAGACAGGGGTTCAGTTAGTTTCC
AATGTCTTTATCCTCTGGTATGGGGCACAATTGGTCATGGAAGGGCAATTATCTGCAGGTCAGTTGATTACTTATAATAT
GTTGCTGAATTATTTTACAACTCCTTTAATTAATATTATCAATCTCCAATCCAAAATTCAGCAAGCCAAAGTAGCCAATA
ATCGTCTTCAAGAAGTTTATGTTGTGGATAAGGAAGAAGAAGGAAAACTTAAAGAGTTATCTTTTAAACAACTTGCTCTT
AAAGGAGTCAGTCACCGTTTTAGTTATCAGCAAGAGACGCTTAGTAAGATTGATTTAACGATTCATAAGGGTGAGAAAAT
CGCCCTCATGGGTAAAAGTGGATCTGGGAAAACAACCTTAGCGAAAATGTTGTCAGGTTATTACACAAAATCTAGTGGTC
ATGTAACCCTAGATAAAGATGCTATTAGCCATGCGGAGCTGCGTCAAATGGTGACTTACGTTCCCCAGCAGACCTATGTG
TTTACAGGAACCATTTTAGAAAATCTGCTATTAGGATATGAAGGAGAAGTTGATGAGAAAAAGCTTCTTAAAGTTTGCCA
ACAAGCTGATATCTTAGAGGATATTCAAAAAATGCCACAAGGTTTTCAGACCCAAGTATCTGAAGACGGTGGTCTATCTG
GTGGTCAAAAACAACGCTTGGCGGTAGCGAGGGCCCTCTTGTCCAAGCAGCCTATCTTGGTTTTTGACGAAGCTACCAGT
GGTCTTGATAGTGATACTGAAAGCAGGGTCATGGCTAATCTTGCTAAGATTAAACGAACAATGATTTTTATTGCTCACCG
CAATAGTGTCCGTCAACATGTCAGTCGTGTGGTGACCATGGTGAGTGGCCAGATTGAGTCAGACAGTCCTAATTTCAATC
CATTCCAGTTTATTTAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (494-640)

• ABC transporter transmembrane region (ABC_membrane) (167-436)

• Peptidase C39 family (Peptidase_C39) (3-139)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus mitis SK321	53.98	98.997	0.534
comA	Streptococcus gordonii str. Challis substr. CH1	53.592	99.713	0.534
comA	Streptococcus mitis NCTC 12261	53.546	98.997	0.53
comA	Streptococcus pneumoniae Rx1	53.401	98.997	0.529
comA	Streptococcus pneumoniae D39	53.401	98.997	0.529
comA	Streptococcus pneumoniae R6	53.401	98.997	0.529
comA	Streptococcus pneumoniae TIGR4	53.256	98.997	0.527
comA/nlmT	Streptococcus mutans UA159	50.29	98.854	0.497