Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   FHI56_RS10630 Genome accession   NZ_CP040804
Coordinates   2060790..2061479 (-) Length   229 a.a.
NCBI ID   WP_002886589.1    Uniprot ID   -
Organism   Streptococcus salivarius strain LAB813     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 2055790..2066479
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FHI56_RS10610 (FHI56_10610) dnaI 2056585..2057487 (-) 903 WP_013990064.1 primosomal protein DnaI -
  FHI56_RS10615 (FHI56_10615) - 2057491..2058666 (-) 1176 WP_013990063.1 DnaD domain protein -
  FHI56_RS10620 (FHI56_10620) nrdR 2058663..2059142 (-) 480 WP_002886592.1 transcriptional regulator NrdR -
  FHI56_RS10625 (FHI56_10625) covS 2059264..2060793 (-) 1530 WP_149561484.1 HAMP domain-containing histidine kinase Regulator
  FHI56_RS10630 (FHI56_10630) covR 2060790..2061479 (-) 690 WP_002886589.1 response regulator transcription factor Regulator
  FHI56_RS10635 (FHI56_10635) - 2061635..2062171 (-) 537 WP_070579518.1 DUF177 domain-containing protein -
  FHI56_RS10640 (FHI56_10640) rsmG 2062470..2063183 (+) 714 WP_049529060.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  FHI56_RS10645 (FHI56_10645) - 2063252..2064616 (+) 1365 WP_073689220.1 TrkH family potassium uptake protein -
  FHI56_RS10650 (FHI56_10650) - 2064656..2065327 (+) 672 WP_002886585.1 TrkA family potassium uptake protein -
  FHI56_RS12000 (FHI56_10655) - 2065417..2065539 (-) 123 Protein_1859 energy-coupling factor transporter transmembrane protein EcfT -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26517.51 Da        Isoelectric Point: 4.6354

>NTDB_id=367379 FHI56_RS10630 WP_002886589.1 2060790..2061479(-) (covR) [Streptococcus salivarius strain LAB813]
MSKRILIVEDEKNLARFVSLELQHEGYDVVTADNGREGLEMALEKDFDLILLDLMLPEMDGFEVTRRLQQEKDTYIMMMT
ARDSIMDIVAGLDRGADDYIVKPFAIEELLARIRATFRRQDIESAKNAPAKASTYRDLKLDVQNRTVVRGDEAIPLTKRE
FDLLNTLLSNMNQVMTREELLLQVWKYDDAIETNVVDVYIRYLRGKIDVPGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 690 bp        

>NTDB_id=367379 FHI56_RS10630 WP_002886589.1 2060790..2061479(-) (covR) [Streptococcus salivarius strain LAB813]
ATGAGCAAACGCATTTTGATTGTTGAAGATGAGAAAAACCTTGCTCGTTTTGTCTCTCTTGAACTTCAACACGAAGGATA
CGACGTTGTGACAGCAGACAACGGACGCGAAGGACTTGAAATGGCACTCGAGAAAGATTTCGATCTTATTCTCTTGGACC
TTATGTTGCCTGAGATGGACGGTTTTGAAGTAACACGTCGTCTCCAACAAGAAAAAGATACTTATATTATGATGATGACA
GCTCGCGATTCAATCATGGACATTGTTGCTGGTTTGGACCGCGGTGCTGATGACTATATTGTAAAACCATTTGCGATTGA
AGAATTGTTGGCACGTATCCGTGCAACCTTCCGTCGCCAAGATATCGAATCTGCTAAGAATGCACCAGCAAAAGCATCAA
CTTATCGTGATTTGAAATTGGATGTTCAAAACCGTACAGTTGTTCGTGGTGATGAAGCAATTCCATTGACAAAACGTGAG
TTTGATTTGTTGAACACACTTTTGAGCAATATGAACCAAGTGATGACCCGTGAGGAACTCTTGCTTCAAGTTTGGAAATA
TGATGACGCCATCGAAACAAACGTGGTAGATGTTTATATTCGTTATTTGCGTGGAAAAATCGACGTTCCAGGTAAGGAAT
CATATATTCAAACAGTACGAGGAATGGGTTACGTTATCCGTGAAAAATGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(152-225)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

99.563

100

0.996
  covR Lactococcus lactis subsp. lactis strain DGCC12653

68.421

99.563

0.681
  vicR Streptococcus mutans UA159

46.352

100

0.472
  micA Streptococcus pneumoniae Cp1015

44.156

100

0.445

Multiple sequence alignment