Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   FHI56_RS10625 Genome accession   NZ_CP040804
Coordinates   2059264..2060793 (-) Length   509 a.a.
NCBI ID   WP_149561484.1    Uniprot ID   A0AB37CN59
Organism   Streptococcus salivarius strain LAB813     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 2054264..2065793
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FHI56_RS10600 (FHI56_10600) - 2054477..2055106 (-) 630 WP_073688676.1 ribonuclease P -
  FHI56_RS10605 (FHI56_10605) der 2055170..2056480 (-) 1311 WP_002886596.1 ribosome biogenesis GTPase Der -
  FHI56_RS10610 (FHI56_10610) dnaI 2056585..2057487 (-) 903 WP_013990064.1 primosomal protein DnaI -
  FHI56_RS10615 (FHI56_10615) - 2057491..2058666 (-) 1176 WP_013990063.1 DnaD domain protein -
  FHI56_RS10620 (FHI56_10620) nrdR 2058663..2059142 (-) 480 WP_002886592.1 transcriptional regulator NrdR -
  FHI56_RS10625 (FHI56_10625) covS 2059264..2060793 (-) 1530 WP_149561484.1 HAMP domain-containing histidine kinase Regulator
  FHI56_RS10630 (FHI56_10630) covR 2060790..2061479 (-) 690 WP_002886589.1 response regulator transcription factor Regulator
  FHI56_RS10635 (FHI56_10635) - 2061635..2062171 (-) 537 WP_070579518.1 DUF177 domain-containing protein -
  FHI56_RS10640 (FHI56_10640) rsmG 2062470..2063183 (+) 714 WP_049529060.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  FHI56_RS10645 (FHI56_10645) - 2063252..2064616 (+) 1365 WP_073689220.1 TrkH family potassium uptake protein -
  FHI56_RS10650 (FHI56_10650) - 2064656..2065327 (+) 672 WP_002886585.1 TrkA family potassium uptake protein -
  FHI56_RS12000 (FHI56_10655) - 2065417..2065539 (-) 123 Protein_1859 energy-coupling factor transporter transmembrane protein EcfT -

Sequence

Protein


Download         Length: 509 a.a.        Molecular weight: 58038.44 Da        Isoelectric Point: 5.2781

>NTDB_id=367378 FHI56_RS10625 WP_149561484.1 2059264..2060793(-) (covS) [Streptococcus salivarius strain LAB813]
MSKLQDKLFGKVTIRKKLTMTTAVVFFLVLSLFTLVVIFSANTLLLQRERQNVNTTIAKVVTYIEKDWDSDEELSPEPLL
AALYSPKNIYASIINGVLSEKHSLDGQVAISNKLYSNQSVFVYDKKGTFIFTSEENTDSPPGMSEVNKLKSVSYKGKRGF
LLQVPIYGKDKKTIVGYAQIFHDLEFYYALKERLVFLLIFLEVGMTVLVIAATVVVLTSILRPMRQLHETMGVITDSPSD
LELRSKIESHDEIGDLAVNFNRMMDKIQENNQMQMRFLSDVSHELRTPIAVIKGHMDLLQRWGKNDPEILEESLEAASHE
ANRMTIMINDMLDSIRVKGSFENHRNDTCDLNSSIRTVIGNFRVLHEDYQFYLNDFESSERLAQIYSQHFEQAITILIDN
AVKYSPVNKEIQVTIKALEDEMLVQVQDNGEGISKEDINHIFERFYRSDKARNRTTTQSGVGIGLSILYQIVEAYRCRID
VSSELGVGTRFDLYIPFADGETTTPQLEL

Nucleotide


Download         Length: 1530 bp        

>NTDB_id=367378 FHI56_RS10625 WP_149561484.1 2059264..2060793(-) (covS) [Streptococcus salivarius strain LAB813]
ATGAGTAAATTACAAGATAAATTATTTGGTAAAGTAACCATTAGAAAAAAGTTGACCATGACAACTGCTGTGGTCTTCTT
TCTTGTATTGTCGTTGTTCACTCTGGTTGTTATTTTTTCAGCTAATACGCTTCTTTTGCAACGTGAACGTCAAAATGTAA
ACACTACAATCGCAAAAGTTGTTACTTACATCGAAAAGGATTGGGATTCGGATGAAGAATTAAGTCCAGAACCGCTCTTA
GCGGCTCTTTATTCGCCTAAAAATATCTATGCATCAATTATTAATGGCGTACTTTCTGAAAAGCACTCTTTGGATGGTCA
AGTTGCAATTTCTAATAAATTATATTCAAATCAGTCAGTTTTTGTGTATGACAAAAAAGGAACCTTTATCTTTACTTCTG
AGGAGAATACAGATTCGCCTCCCGGTATGTCCGAGGTAAACAAACTGAAGTCAGTATCCTATAAAGGAAAGCGTGGTTTC
TTACTACAAGTTCCAATTTACGGTAAGGATAAAAAGACCATCGTTGGCTATGCCCAGATTTTCCATGATTTGGAATTCTA
CTATGCTCTTAAAGAGCGTTTGGTTTTCTTGTTGATTTTCCTAGAAGTGGGGATGACTGTCCTAGTTATCGCAGCAACTG
TAGTTGTCTTGACATCTATTCTTCGTCCGATGAGACAGTTGCACGAAACGATGGGAGTTATTACCGATTCGCCAAGTGAT
TTGGAACTTCGTTCTAAGATTGAAAGTCACGATGAAATTGGTGATTTGGCGGTTAACTTTAACCGCATGATGGATAAAAT
TCAAGAAAATAATCAGATGCAGATGCGTTTCTTGAGTGACGTCAGTCATGAATTGCGTACGCCGATTGCGGTTATCAAGG
GGCATATGGACCTCTTGCAACGTTGGGGTAAAAATGACCCTGAGATTCTTGAAGAAAGTCTTGAGGCTGCAAGTCACGAG
GCCAACCGTATGACGATTATGATTAATGATATGTTGGATTCTATCCGTGTCAAAGGATCATTTGAAAATCATAGAAACGA
TACTTGTGATTTGAATTCTTCAATCCGTACGGTTATTGGGAACTTCCGTGTCTTGCATGAAGATTATCAATTTTATCTCA
ATGATTTCGAAAGTTCAGAGCGTCTAGCACAGATTTATAGTCAGCACTTTGAACAGGCGATCACCATTTTGATTGATAAT
GCGGTCAAGTATTCGCCTGTCAATAAGGAAATACAGGTTACTATTAAAGCATTGGAAGATGAAATGTTGGTACAAGTGCA
AGATAACGGTGAGGGGATTTCAAAAGAAGATATCAATCATATTTTTGAACGTTTCTATCGTTCAGATAAGGCACGTAACC
GTACAACAACTCAATCTGGTGTTGGTATTGGTTTGTCAATCCTTTATCAAATTGTGGAAGCTTATCGCTGCCGTATTGAT
GTTAGTTCTGAACTTGGTGTTGGAACACGTTTCGACCTTTACATTCCATTTGCGGATGGAGAAACGACGACACCTCAACT
TGAGCTTTAA

Domains

Predicted by InterproScan.

HAMP domain (HAMP)

(217-269)

His Kinase A (phospho-acceptor) domain (HisKA)

(274-333)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(388-497)

ArlS sensor domain (ArlS_N)

(43-191)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Streptococcus salivarius strain HSISS4

98.821

100

0.988

Multiple sequence alignment