Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   FHI56_RS10385 Genome accession   NZ_CP040804
Coordinates   2007740..2009059 (-) Length   439 a.a.
NCBI ID   WP_111686476.1    Uniprot ID   A0AB37CPR0
Organism   Streptococcus salivarius strain LAB813     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2002740..2014059
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FHI56_RS10375 (FHI56_10375) hpf 2006470..2007018 (-) 549 WP_002883786.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  FHI56_RS10380 (FHI56_10380) - 2007097..2007759 (-) 663 WP_111686477.1 ComF family protein -
  FHI56_RS10385 (FHI56_10385) comFA/cflA 2007740..2009059 (-) 1320 WP_111686476.1 DEAD/DEAH box helicase Machinery gene
  FHI56_RS10390 (FHI56_10390) - 2009114..2009740 (+) 627 WP_045771735.1 YigZ family protein -
  FHI56_RS10395 (FHI56_10395) cysK 2009842..2010768 (+) 927 WP_002883742.1 cysteine synthase A -
  FHI56_RS10400 (FHI56_10400) - 2010947..2011606 (-) 660 WP_002886636.1 CBS and ACT domain-containing protein -
  FHI56_RS10405 (FHI56_10405) - 2011741..2012451 (-) 711 WP_002883761.1 ABC transporter ATP-binding protein -
  FHI56_RS10410 (FHI56_10410) - 2012451..2013215 (-) 765 WP_002886634.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 439 a.a.        Molecular weight: 50687.79 Da        Isoelectric Point: 9.0241

>NTDB_id=367376 FHI56_RS10385 WP_111686476.1 2007740..2009059(-) (comFA/cflA) [Streptococcus salivarius strain LAB813]
MVPKEYYGRLFTKEQLPVDYHSEAFTLESMIKVDKQLRCKRCYSQIEEDWQLPEGQYYCRACIVFGRNQEGKELYYFPSK
TSEIEFPVLKWLGELTPYQAEVSEKLLETYQKQKDSLVHAVTGAGKTEMIYKIVAYVLESKGNVAIASPRVDVCRELFLR
MQRAFTCSISLLHAESEPYDGSPLVIATTHQLLKFYQNFDLVIVDEVDAFPFVGNVMLNHAVEQAKKETGRYIYLTATST
ISLEEQVRLGAIEKHHLARRFHGNPLVLPKFCWQGRLQKFLMRGKLPRPLLYQIKKQRKSKFPLLIFFPNIAIGEKFTSI
LQKYLPDEKMAFISSKSEERSATVEQFREKELSILVTTTILERGVTFPQVDVFVCMANHHLYTSSSLIQIGGRVGRSPDR
PTGKLYFFHEGLSKSMLRCREEIKVMNKKGGFNNEVSTM

Nucleotide


Download         Length: 1320 bp        

>NTDB_id=367376 FHI56_RS10385 WP_111686476.1 2007740..2009059(-) (comFA/cflA) [Streptococcus salivarius strain LAB813]
ATGGTACCTAAAGAATATTATGGACGACTATTTACGAAAGAACAGTTGCCAGTGGACTATCACTCAGAGGCTTTTACATT
AGAAAGCATGATAAAGGTCGATAAACAACTTAGATGTAAAAGATGTTACAGTCAGATAGAGGAAGATTGGCAATTACCGG
AAGGTCAGTATTATTGCAGAGCATGTATTGTCTTTGGCAGAAACCAAGAAGGAAAAGAACTTTATTATTTTCCTTCAAAA
ACATCTGAAATTGAATTTCCTGTTTTGAAGTGGTTGGGGGAACTGACTCCCTATCAAGCTGAGGTCTCAGAGAAGCTTTT
AGAAACATATCAAAAACAGAAAGACAGCCTCGTACATGCTGTGACCGGTGCTGGTAAGACCGAGATGATTTATAAAATCG
TTGCCTATGTTCTTGAAAGTAAAGGTAATGTAGCTATCGCAAGTCCTCGGGTTGATGTTTGTCGAGAGTTATTTCTACGT
ATGCAGAGGGCTTTTACTTGTAGTATTTCTCTGCTTCATGCTGAGAGTGAACCATATGATGGTAGTCCGCTTGTAATAGC
TACCACCCATCAATTACTAAAGTTTTACCAGAACTTTGACCTAGTTATCGTTGATGAGGTTGATGCATTCCCTTTTGTAG
GAAATGTCATGTTAAATCATGCTGTGGAGCAGGCAAAGAAGGAAACCGGTCGCTATATTTATTTAACAGCGACTTCTACA
ATATCTTTAGAAGAGCAAGTTCGACTTGGAGCTATAGAAAAACATCACCTTGCCAGACGTTTCCATGGAAATCCTTTAGT
ACTTCCTAAATTCTGCTGGCAAGGAAGATTACAAAAATTTCTAATGAGAGGCAAGCTTCCAAGACCCCTTCTTTATCAGA
TTAAAAAGCAACGTAAATCAAAGTTTCCTCTATTAATATTTTTCCCAAATATAGCGATAGGTGAAAAGTTTACTAGCATT
CTGCAAAAATATCTTCCAGATGAAAAAATGGCCTTTATTTCTTCAAAAAGCGAGGAGCGTTCAGCTACCGTAGAGCAGTT
CCGGGAAAAAGAGTTATCCATCTTAGTGACAACAACTATCCTTGAACGTGGTGTAACCTTTCCACAAGTAGATGTTTTTG
TTTGTATGGCAAATCATCACTTATACACTAGTTCGAGTCTTATTCAGATAGGAGGTCGAGTTGGAAGATCCCCAGATAGA
CCGACAGGAAAGCTTTATTTCTTTCATGAAGGACTATCCAAATCTATGCTTCGTTGTCGAGAAGAAATAAAAGTTATGAA
TAAAAAAGGAGGATTTAACAATGAAGTGTCTACTATGTAA

Domains

Predicted by InterproScan.

Type III restriction enzyme, res subunit (ResIII)

(94-207)

Helicase conserved C-terminal domain (Helicase_C)

(290-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

55.684

98.178

0.547
  comFA/cflA Streptococcus pneumoniae D39

55.684

98.178

0.547
  comFA/cflA Streptococcus pneumoniae R6

55.684

98.178

0.547
  comFA/cflA Streptococcus pneumoniae TIGR4

55.684

98.178

0.547
  comFA/cflA Streptococcus mitis NCTC 12261

54.839

98.861

0.542
  comFA/cflA Streptococcus mitis SK321

54.292

98.178

0.533
  comFA Lactococcus lactis subsp. cremoris KW2

45.368

95.9

0.435
  comFA Latilactobacillus sakei subsp. sakei 23K

38.303

99.317

0.38

Multiple sequence alignment