Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA/cilB/dalA   Type   Machinery gene
Locus tag   FDP16_RS05875 Genome accession   NZ_CP040798
Coordinates   1138100..1138942 (+) Length   280 a.a.
NCBI ID   WP_176798938.1    Uniprot ID   A0A7H8V0S1
Organism   Streptococcus sanguinis strain CGMH058     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1133100..1143942
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FDP16_RS05840 (FDP16_06080) ylqF 1133102..1133953 (+) 852 WP_176798932.1 ribosome biogenesis GTPase YlqF -
  FDP16_RS05845 (FDP16_06085) - 1133940..1134710 (+) 771 WP_176798933.1 ribonuclease HII -
  FDP16_RS05850 (FDP16_06090) - 1134721..1135647 (+) 927 WP_176798934.1 ROK family protein -
  FDP16_RS05855 (FDP16_06095) - 1135647..1135778 (+) 132 Protein_1135 DNA processing protein DprA -
  FDP16_RS05860 (FDP16_06100) - 1135805..1136569 (+) 765 WP_176798935.1 ribonuclease HII -
  FDP16_RS05865 (FDP16_06105) - 1136587..1137429 (+) 843 WP_176798936.1 PRD domain-containing protein -
  FDP16_RS05870 (FDP16_06110) - 1137405..1137968 (+) 564 WP_176798937.1 sugar O-acetyltransferase -
  FDP16_RS05875 (FDP16_06115) dprA/cilB/dalA 1138100..1138942 (+) 843 WP_176798938.1 DNA-processing protein DprA Machinery gene
  FDP16_RS05880 (FDP16_06120) topA 1139027..1141120 (+) 2094 WP_176798939.1 type I DNA topoisomerase -
  FDP16_RS05885 (FDP16_06125) - 1141177..1141659 (+) 483 Protein_1141 phosphoribosylanthranilate isomerase -
  FDP16_RS05890 (FDP16_06130) trmFO 1141760..1143088 (+) 1329 Protein_1142 methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO -

Sequence

Protein


Download         Length: 280 a.a.        Molecular weight: 30994.66 Da        Isoelectric Point: 6.7409

>NTDB_id=367221 FDP16_RS05875 WP_176798938.1 1138100..1138942(+) (dprA/cilB/dalA) [Streptococcus sanguinis strain CGMH058]
MNNFEIYKMKKAGLTNHQVLNVLRYAESRDGKLSLRDKAVVSECRNPALFIEKYKRLDLPALKEEFELFPSFSILDDIYP
WDLCEIYDAPTLLFYQGNLNLLELPKTAVVGSRDSSKQGNASVQKIVKELNNELVIVSGLARGIDTAAHMAALQNGGQTI
AVIGTGLDVFYPKANKKLQAYIGKNHLLLTEYGPGEQPLKFHFPERNRIIAGLCRGVIVAEAKMRSGSLITCERAMEEGR
DVFAIPGSILDGKSDGCHHLIQEGAKCITSGSDVLSEFDF

Nucleotide


Download         Length: 843 bp        

>NTDB_id=367221 FDP16_RS05875 WP_176798938.1 1138100..1138942(+) (dprA/cilB/dalA) [Streptococcus sanguinis strain CGMH058]
ATGAATAATTTTGAAATTTATAAAATGAAAAAAGCTGGCTTGACTAATCATCAGGTTTTAAATGTTTTGAGATACGCTGA
GAGTAGAGATGGCAAGCTTTCTCTCCGAGATAAGGCTGTCGTATCTGAGTGCCGCAATCCTGCGCTCTTTATAGAGAAAT
ACAAGAGGCTTGATTTACCAGCTTTGAAGGAAGAATTTGAACTTTTCCCGTCCTTTTCTATCTTGGATGATATTTATCCT
TGGGATTTATGCGAGATTTATGATGCCCCGACTTTGTTATTTTATCAGGGAAATCTAAATCTACTAGAATTGCCCAAGAC
AGCGGTCGTTGGCAGTCGAGACAGCAGCAAGCAAGGAAATGCCTCCGTACAAAAGATTGTCAAGGAGCTAAATAATGAAT
TGGTTATCGTCAGCGGCCTGGCTCGTGGAATAGATACAGCGGCTCATATGGCTGCCTTGCAAAACGGGGGGCAGACGATT
GCTGTCATTGGTACTGGATTAGACGTCTTTTATCCCAAGGCCAACAAAAAATTACAAGCTTACATTGGAAAAAATCATTT
ATTGCTGACAGAGTATGGTCCGGGTGAACAGCCCTTGAAATTTCATTTCCCAGAGCGGAATCGTATTATCGCTGGTCTCT
GTCGAGGCGTCATTGTGGCAGAAGCCAAGATGCGCTCAGGCAGCCTGATTACCTGTGAGCGAGCCATGGAAGAAGGCCGG
GATGTCTTTGCTATTCCGGGGTCAATTTTAGATGGAAAATCTGACGGTTGCCATCATTTGATTCAAGAGGGCGCAAAGTG
TATCACATCAGGCTCTGACGTCCTTTCTGAGTTTGATTTTTAA

Domains

Predicted by InterproScan.

DNA processing protein A sterile alpha motif domain (SAM_DprA)

(1-61)

DNA recombination-mediator protein A (DNA_processg_A)

(74-269)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7H8V0S1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA/cilB/dalA Streptococcus mitis NCTC 12261

76.786

100

0.768
  dprA/cilB/dalA Streptococcus pneumoniae Rx1

76.429

100

0.764
  dprA/cilB/dalA Streptococcus pneumoniae D39

76.429

100

0.764
  dprA/cilB/dalA Streptococcus pneumoniae R6

76.429

100

0.764
  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

76.429

100

0.764
  dprA/cilB/dalA Streptococcus mitis SK321

76.071

100

0.761
  dprA Streptococcus mutans UA159

66.786

100

0.668
  dprA Lactococcus lactis subsp. cremoris KW2

57.554

99.286

0.571

Multiple sequence alignment