Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   FDP16_RS02615 Genome accession   NZ_CP040798
Coordinates   520756..522609 (+) Length   617 a.a.
NCBI ID   WP_176798471.1    Uniprot ID   A0A7H8UYU3
Organism   Streptococcus sanguinis strain CGMH058     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 515756..527609
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FDP16_RS02600 (FDP16_02705) fmt 517759..518694 (+) 936 WP_176798469.1 methionyl-tRNA formyltransferase -
  FDP16_RS02605 (FDP16_02710) rsmB 518684..520000 (+) 1317 WP_176798470.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  FDP16_RS02610 (FDP16_02715) - 520019..520759 (+) 741 WP_002903268.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  FDP16_RS02615 (FDP16_02720) stkP 520756..522609 (+) 1854 WP_176798471.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  FDP16_RS02620 (FDP16_02725) liaF 522755..523450 (+) 696 WP_002893496.1 cell wall-active antibiotics response protein LiaF -
  FDP16_RS02625 (FDP16_02730) - 523447..524466 (+) 1020 WP_176798472.1 sensor histidine kinase -
  FDP16_RS02630 (FDP16_02735) - 524444..525076 (+) 633 WP_002926512.1 response regulator transcription factor -
  FDP16_RS02635 (FDP16_02740) - 525116..526516 (+) 1401 WP_176798473.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  FDP16_RS02640 (FDP16_02745) - 526516..526878 (+) 363 WP_101771704.1 S1 RNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 617 a.a.        Molecular weight: 67320.11 Da        Isoelectric Point: 6.4426

>NTDB_id=367209 FDP16_RS02615 WP_176798471.1 520756..522609(+) (stkP) [Streptococcus sanguinis strain CGMH058]
MIQIGKIFAGRYKIIKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREAKAMADLDHPHIVRITDIG
EEDGQQYLAMEYVAGLDLKRYIKENSPISNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNVLLTPDGNAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSIISENPNVP
QALENVVIKATAKKLTDRYQSVAEMYVDLSSSLSYERRNEKKLVFDDVAKADTKTLPKISPVPQPAVPSVKSTPPKAEAT
EVKEETSDAVKKAPKKRRLRTRYKVLFFAVLLVLAAFVVLLYNSPSNTSVPDVSGQTVAEARSAIEAKKLVVGDEKEEYS
DNVESGKVIKTDPQANSQRREGSKIDLIISKGPKTFVMEDYVGQAKSAVVENLKTNYNVSEKLIEIVEEESDEYEPGQVI
RQSPAAGSTYDLTSNHKIKLTVAKEVTSVAMPDFGSMQYTYANARSYLIQMGISSSRIERVVDRSVTSTQADLVTSQSPA
AGQTIDLKSNEKITLYVTEATTPSSSSSSSSSSSSSSKSSSSSEDSGHGTSSSSSDS

Nucleotide


Download         Length: 1854 bp        

>NTDB_id=367209 FDP16_RS02615 WP_176798471.1 520756..522609(+) (stkP) [Streptococcus sanguinis strain CGMH058]
ATGATTCAAATCGGCAAAATCTTTGCCGGGCGATATAAAATCATCAAGCAGATTGGCCGCGGAGGCATGGCAGATGTCTA
TCTGGCCAAGGACTTGATTTTGGATGGTGAGGAAGTTGCGGTAAAGGTTCTTAGGACCAATTACCAGACAGATCCTATCG
CTGTCGCGCGTTTCCAGCGGGAAGCTAAGGCGATGGCTGACTTGGACCATCCGCACATCGTTCGGATTACTGATATTGGA
GAAGAAGACGGCCAGCAGTATCTGGCTATGGAATACGTGGCGGGTCTGGACCTCAAGCGCTATATCAAAGAGAATTCTCC
TATTTCAAATGAAGAAGCAGTCAGAATCATGGGACAAATCTTGCTGGCAATGCGCCTAGCGCATACACGCGGCATTGTCC
ATCGTGACCTGAAACCACAAAATGTCCTCTTAACCCCGGATGGCAATGCCAAGGTAACAGACTTTGGGATTGCGGTGGCC
TTTGCGGAGACAAGTCTGACTCAGACTAACTCAATGCTAGGCTCAGTTCATTATCTATCGCCTGAGCAGGCACGTGGCTC
TAAAGCAACTGTTCAGAGTGATATTTATGCGATGGGGATTATTTTTTATGAAATGCTGACTGGTCATATCCCTTATGACG
GGGATAGTGCCGTTACGATTGCCTTGCAGCATTTCCAAAAGCCGCTGCCATCCATTATTTCTGAAAATCCTAATGTGCCT
CAGGCCTTGGAAAATGTCGTCATTAAGGCAACAGCCAAAAAACTGACGGATCGCTATCAATCAGTTGCAGAGATGTATGT
CGACTTGTCCAGCAGCTTATCCTACGAGCGCCGTAATGAAAAGAAATTAGTCTTTGATGATGTAGCGAAAGCAGACACCA
AGACCTTGCCAAAAATCTCACCTGTACCTCAGCCGGCAGTTCCATCTGTTAAGTCAACCCCGCCTAAAGCGGAAGCGACT
GAAGTCAAGGAAGAGACATCTGATGCGGTTAAGAAAGCTCCAAAGAAACGCCGTTTGAGAACGCGTTACAAGGTTCTTTT
CTTTGCAGTCCTATTGGTTTTGGCTGCCTTTGTCGTCCTTCTCTATAACAGCCCGTCCAATACCAGCGTGCCAGATGTTT
CTGGTCAGACTGTAGCAGAGGCTCGCTCCGCTATTGAAGCTAAGAAGCTGGTTGTCGGGGATGAAAAGGAAGAATACAGC
GACAATGTCGAATCCGGCAAAGTCATTAAAACTGATCCACAGGCCAACAGTCAGCGCCGCGAAGGCAGCAAGATTGACCT
GATTATTTCCAAGGGACCCAAGACCTTTGTCATGGAAGATTATGTCGGTCAAGCAAAATCAGCCGTAGTTGAAAATCTGA
AAACAAACTATAATGTTTCTGAGAAATTGATTGAGATTGTTGAGGAGGAATCGGACGAGTACGAGCCAGGTCAGGTCATT
CGCCAGTCACCGGCAGCTGGTTCGACCTATGATTTGACTTCTAATCATAAGATCAAGCTGACAGTGGCTAAAGAAGTGAC
TAGTGTGGCCATGCCTGACTTTGGCAGCATGCAGTACACCTACGCTAATGCACGTTCTTACTTGATTCAAATGGGAATTT
CTTCGTCTCGAATTGAGCGAGTTGTTGACCGTTCGGTCACTTCGACTCAGGCAGACTTGGTAACTTCCCAGTCACCAGCG
GCAGGTCAGACAATTGACCTCAAGTCTAATGAAAAAATCACTCTTTATGTGACTGAAGCAACGACACCATCATCATCTAG
CTCGTCATCCTCATCGTCTAGTAGCAGCTCAAAGAGCAGCTCATCGTCTGAAGATAGTGGACATGGAACAAGTTCTAGCT
CATCTGATAGTTGA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(437-504)

PASTA domain (PASTA)

(370-431)

PASTA domain (PASTA)

(509-578)

Protein kinase domain (Pkinase)

(12-232)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7H8UYU3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

63.411

97.893

0.621
  stkP Streptococcus pneumoniae D39

63.079

97.893

0.617
  stkP Streptococcus pneumoniae R6

63.079

97.893

0.617
  stkP Streptococcus pneumoniae Rx1

62.914

97.893

0.616
  pknB Streptococcus mutans UA159

58.603

95.138

0.558
  stkP/pknB Streptococcus salivarius strain HSISS4

55.426

97.083

0.538

Multiple sequence alignment