Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   FDP16_RS02050 Genome accession   NZ_CP040798
Coordinates   402263..403015 (+) Length   250 a.a.
NCBI ID   WP_176798390.1    Uniprot ID   A0A7H8V119
Organism   Streptococcus sanguinis strain CGMH058     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 397263..408015
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FDP16_RS02035 (FDP16_02120) - 397358..398923 (-) 1566 WP_176798387.1 ABC transporter substrate-binding protein/permease -
  FDP16_RS02040 (FDP16_02125) - 399055..400950 (+) 1896 WP_176798388.1 DUF2207 domain-containing protein -
  FDP16_RS02045 (FDP16_02130) - 401090..401932 (+) 843 WP_176798389.1 undecaprenyl-diphosphate phosphatase -
  FDP16_RS02050 (FDP16_02135) mecA 402263..403015 (+) 753 WP_176798390.1 adaptor protein MecA Regulator
  FDP16_RS02055 (FDP16_02140) - 403006..404172 (+) 1167 WP_002893637.1 glycosyltransferase family 4 protein -
  FDP16_RS02060 (FDP16_02145) sufC 404262..405032 (+) 771 WP_002893635.1 Fe-S cluster assembly ATPase SufC -
  FDP16_RS02065 (FDP16_02150) sufD 405074..406336 (+) 1263 WP_176798391.1 Fe-S cluster assembly protein SufD -
  FDP16_RS02070 (FDP16_02155) - 406378..407610 (+) 1233 WP_176798392.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 250 a.a.        Molecular weight: 28884.56 Da        Isoelectric Point: 3.9920

>NTDB_id=367199 FDP16_RS02050 WP_176798390.1 402263..403015(+) (mecA) [Streptococcus sanguinis strain CGMH058]
MEMKQISDSTIKITIQLEDLEERGMEMADFLVPQEKTEEFFYTILDELEMPDNFLDSGMLSFRVTPKPDKVDVFVTKSKL
DKNLSFEDLADLPDMDELSRMSPDEFLKTLEKSIFEKSKEDIEAVQSLEIAEAEEREQLSQEAADEQSAENAERYIYYIL
RFEDIKAAAAFAQTVDYKIDLSELYKYDSAYYLTILVDVEGFPERYPAWLLAKMREFADDSDITRAVLQEHGHLLLVTDA
VSGLQKVECL

Nucleotide


Download         Length: 753 bp        

>NTDB_id=367199 FDP16_RS02050 WP_176798390.1 402263..403015(+) (mecA) [Streptococcus sanguinis strain CGMH058]
ATGGAAATGAAACAGATTAGTGATTCGACCATAAAAATCACGATTCAGCTGGAAGATTTGGAAGAGCGTGGCATGGAAAT
GGCCGATTTCTTGGTTCCCCAAGAAAAGACGGAAGAATTTTTCTATACCATCTTAGATGAGTTGGAAATGCCGGATAATT
TTTTAGATAGCGGCATGCTGAGTTTTCGTGTGACGCCTAAACCAGATAAGGTGGATGTTTTTGTTACCAAGTCTAAATTG
GATAAGAATCTGAGTTTTGAGGATTTGGCAGATCTACCAGACATGGATGAGCTGTCTCGTATGTCTCCAGATGAATTCCT
CAAGACATTGGAAAAGAGCATTTTTGAAAAGAGTAAGGAAGACATAGAAGCAGTCCAATCTTTGGAAATAGCCGAAGCAG
AGGAAAGGGAGCAGCTTTCTCAAGAAGCGGCTGATGAGCAGTCAGCAGAAAATGCAGAGCGTTATATTTACTACATCCTG
CGATTTGAAGATATTAAGGCTGCTGCGGCCTTTGCCCAGACGGTGGACTATAAGATTGACTTATCAGAGCTTTATAAGTA
TGATTCGGCTTATTATTTGACGATTTTGGTGGATGTTGAGGGCTTCCCGGAGCGCTATCCTGCTTGGCTCTTGGCCAAAA
TGCGTGAATTCGCAGATGATTCAGATATCACTCGGGCAGTGCTGCAGGAGCACGGTCATCTGCTTTTGGTGACAGATGCG
GTCTCCGGCCTGCAGAAGGTTGAATGCCTATGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7H8V119

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

68.826

98.8

0.68
  mecA Streptococcus pneumoniae D39

68.826

98.8

0.68
  mecA Streptococcus pneumoniae R6

68.826

98.8

0.68
  mecA Streptococcus pneumoniae TIGR4

68.421

98.8

0.676
  mecA Streptococcus mutans UA159

50.602

99.6

0.504
  mecA Streptococcus thermophilus LMD-9

48.996

99.6

0.488
  mecA Streptococcus thermophilus LMG 18311

48.594

99.6

0.484

Multiple sequence alignment