Detailed information NTG0036623

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: SMUNN2025_RS09770
• Genome accession: NC_013928
• Coordinates: 2011123..2012331 (+)
• Length: 402 a.a.
• NCBI ID: WP_012997995.1
• Uniprot ID: -
• Organism: Streptococcus mutans NN2025
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2006123..2017331

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SMUNN2025_RS09760 (SmuNN2025_1892)	-	2009424..2010086 (-)	663	WP_002262652.1	YoaK family protein	-
SMUNN2025_RS09765 (SmuNN2025_1893)	rlmH	2010438..2010917 (-)	480	WP_002262651.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
SMUNN2025_RS09770 (SmuNN2025_1894)	htrA	2011123..2012331 (+)	1209	WP_012997995.1	S1C family serine protease	Regulator
SMUNN2025_RS09775 (SmuNN2025_1895)	spo0J	2012809..2013579 (+)	771	WP_002269456.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 402 a.a.
• Molecular weight: 43098.57 Da
• Isoelectric Point: 8.8092

>NTDB_id=36623 SMUNN2025_RS09770 WP_012997995.1 2011123..2012331(+) (htrA) [Streptococcus mutans NN2025]
MNNTKSHPFLKWFIPFLVIFLTFILGVISTLTFNWITGNKSFSNNGKTTVSNVIYDTKSNTTKAVKNVKNTVVSVINYQK
TDNNYYNYDSGSQEKNKSEDGLGVYGEGSGVIYKKDGDSAYLVTNNHVVKDAEKLEIMMANGKKVVGKLVGSDTYSDLAV
IKISSKYVTTVAEFANSDKIKVGEPAIAIGSPLGSDYANSVTEGIVSSLSRTVTSQNENGETISTNAIQTDAAINPGNSG
GALINIKGQVIGINSSKIASSNNSNSGVAVEGMGFAIPSNDVVSIINQLEENGEVVRPALGISMANLSEASTSGRDTLKI
PSDVTSGIVVLSTQSGMPADGKLKKYDVITEIDGKKVASISDLQSILYKHKKGDKIKLTFYREKDKQTVEIQLTKTSQDL
NH

Nucleotide

• Length: 1209 bp

>NTDB_id=36623 SMUNN2025_RS09770 WP_012997995.1 2011123..2012331(+) (htrA) [Streptococcus mutans NN2025]
GTGAATAATACGAAATCTCACCCTTTTTTAAAATGGTTTATACCTTTTTTAGTTATTTTTTTAACTTTTATTTTAGGGGT
CATATCAACACTTACCTTTAATTGGATAACTGGTAACAAATCGTTTTCTAACAATGGAAAAACAACTGTTAGTAATGTCA
TTTATGATACCAAATCTAACACTACCAAGGCTGTTAAAAATGTCAAAAATACAGTTGTATCTGTCATCAATTATCAAAAA
ACAGATAATAATTATTACAATTATGACAGCGGTTCTCAAGAAAAAAATAAATCAGAGGATGGTCTAGGAGTCTACGGTGA
AGGTTCTGGTGTTATCTACAAAAAAGATGGCGATAGTGCTTATTTAGTCACAAACAATCATGTCGTTAAAGATGCAGAAA
AGTTAGAAATCATGATGGCTAATGGTAAAAAAGTTGTCGGTAAATTAGTAGGTTCTGATACTTATTCTGATCTGGCTGTT
ATTAAAATTTCTTCTAAGTATGTTACGACAGTTGCTGAATTTGCTAATTCGGATAAAATAAAAGTTGGAGAACCAGCAAT
CGCTATTGGTAGCCCTTTAGGCAGTGATTATGCTAATTCTGTAACAGAAGGAATTGTTTCAAGTCTCAGTCGTACAGTAA
CTTCACAAAATGAAAATGGCGAAACAATTTCAACTAATGCTATTCAAACAGATGCAGCTATTAACCCTGGTAATTCTGGT
GGCGCTTTAATTAATATCAAAGGACAAGTTATTGGTATCAATTCAAGTAAAATTGCATCAAGTAATAACTCAAATAGTGG
CGTTGCTGTTGAAGGAATGGGCTTTGCAATTCCTTCAAACGATGTTGTCTCTATTATTAATCAATTAGAAGAAAATGGTG
AAGTTGTTAGACCCGCTCTTGGTATTTCAATGGCTAATCTTAGTGAAGCTTCAACAAGTGGAAGAGATACTTTAAAAATA
CCAAGTGATGTCACAAGCGGTATTGTTGTTCTTTCAACACAAAGTGGTATGCCAGCAGATGGGAAGCTGAAGAAATATGA
TGTCATTACAGAAATTGATGGGAAGAAGGTAGCGTCTATCAGCGATCTTCAAAGTATTCTTTACAAACACAAAAAGGGAG
ATAAAATTAAACTCACTTTCTATCGCGAAAAAGATAAACAAACAGTTGAGATCCAATTAACTAAAACAAGTCAAGATTTG
AATCATTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (298-393)

• Trypsin-like peptidase domain (Trypsin_2) (108-253)

• Peptidase family M50 (Peptidase_M50) (227-398)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	99.751	100	0.998
htrA	Streptococcus gordonii str. Challis substr. CH1	55.89	99.254	0.555
htrA	Streptococcus mitis NCTC 12261	54.545	98.507	0.537
htrA	Streptococcus pneumoniae Rx1	54.177	98.259	0.532
htrA	Streptococcus pneumoniae D39	54.177	98.259	0.532
htrA	Streptococcus pneumoniae R6	54.177	98.259	0.532
htrA	Streptococcus pneumoniae TIGR4	54.177	98.259	0.532