Detailed information NTG0036574

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: SMUNN2025_RS01395
• Genome accession: NC_013928
• Coordinates: 283263..285554 (+)
• Length: 763 a.a.
• NCBI ID: WP_024784858.1
• Uniprot ID: -
• Organism: Streptococcus mutans NN2025
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 278263..290554

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SMUNN2025_RS01375 (SmuNN2025_0258)	serS	278568..279848 (-)	1281	WP_012997573.1	serine--tRNA ligase	-
SMUNN2025_RS01380 (SmuNN2025_0259)	-	280420..281445 (+)	1026	WP_195914938.1	acyltransferase	-
SMUNN2025_RS01385 (SmuNN2025_0260)	-	281683..282051 (-)	369	WP_002263350.1	DUF956 family protein	-
SMUNN2025_RS01390 (SmuNN2025_0261)	-	282370..282723 (+)	354	WP_002282605.1	hypothetical protein	-
SMUNN2025_RS01395 (SmuNN2025_0262)	comA/nlmT	283263..285554 (+)	2292	WP_024784858.1	peptide cleavage/export ABC transporter	Regulator
SMUNN2025_RS01400 (SmuNN2025_0263)	-	285886..286812 (-)	927	WP_002265465.1	PTS system mannose/fructose/sorbose family transporter subunit IID	-
SMUNN2025_RS01405 (SmuNN2025_0264)	-	286827..287645 (-)	819	WP_002263354.1	PTS mannose/fructose/sorbose transporter subunit IIC	-
SMUNN2025_RS01410 (SmuNN2025_0265)	-	287680..288672 (-)	993	WP_002265466.1	PTS sugar transporter subunit IIB	-
SMUNN2025_RS01415 (SmuNN2025_0266)	-	289547..290017 (-)	471	WP_002263356.1	hypothetical protein	-

Sequence

Protein

• Length: 763 a.a.
• Molecular weight: 86444.80 Da
• Isoelectric Point: 8.1547

>NTDB_id=36574 SMUNN2025_RS01395 WP_024784858.1 283263..285554(+) (comA/nlmT) [Streptococcus mutans NN2025]
MNIFSYLLLTVVSVLLVNLFLEFIRYFFKTTPAMNKVNSKKTSNFLWSRTRRFKFVPQVDNRDCGPAALASIAKHYGSYY
SLVHLRELTKTDRQGTTALGIIEAAKNIGFETYSLDADMSLFNYDDLIYPFIVHVVKNKRLQHYYVVYNDEGDSLIIGDP
DPSVKVIRMSKERFQHEWTGVAIFFSPKDDYQPQKDKRRGLTSFIPSFLKQKSLLFYIIMASLIITLIEIIGAFYLQVML
DEYIPSQKISTLGFITLGLIITYVAQQIIAFAKEYLLIILGQRLVIDVILTYIKHIFILPMSFFSTRRTGEITSRFTDAN
QIIDAVASTIFSIFLDISMVFIVGGVLLIQNVVLFFLALLCVPIYIIIVFAFMKMFGYLNYEVMESNAIMSSSVIEDING
IETIKSLTSEEVSYQRIDKEFVDFLEKSFRLHKYGAIQVSIKTAAKLILNIVILWYGARLVMTGKISVGQMIAFNVLLGY
FSSPIENMINLQIKLQSARIANTRLNEVYLVDSEFENNGELSEGSFLDGDISFEKLSYKYGYGRDTLSDINLTIKKGSKV
SLVGASGSGKTTLAKMIVNFYEPIQGLIRLNGYDLKDIDKTVLRQHINYLPQQAYVFSGTIMDNLTLGAKKDINQEDIIR
ACEIAEIHSDIEQMPLGYQTELSDGTGVSGGQKQRIALARALLTQAPVLILDEATSSLDVLTEKKIVNNLMAMTNKTIVF
VAHRLSIAQRTDRIIVMDQGKIVEEGSHKELLAHKGFYYKLFN

Nucleotide

• Length: 2292 bp

>NTDB_id=36574 SMUNN2025_RS01395 WP_024784858.1 283263..285554(+) (comA/nlmT) [Streptococcus mutans NN2025]
ATGAACATATTTTCTTATCTTCTTTTGACTGTAGTTTCAGTATTATTAGTCAATTTATTCTTAGAATTTATAAGATACTT
TTTTAAAACAACTCCAGCAATGAATAAGGTAAATTCTAAGAAAACTTCAAATTTTTTATGGAGTCGAACTAGACGTTTTA
AATTTGTACCACAAGTCGATAATAGAGACTGTGGCCCGGCTGCTCTAGCCTCTATTGCCAAACATTATGGTTCATATTAT
TCCTTGGTTCATCTGCGTGAACTTACAAAGACAGATCGACAAGGCACCACAGCATTAGGCATCATTGAAGCTGCCAAAAA
TATTGGATTTGAAACTTACTCGCTAGATGCTGATATGTCTTTATTTAATTATGATGACCTTATTTACCCTTTTATTGTTC
ACGTTGTTAAAAATAAACGTCTTCAACATTACTATGTTGTTTATAACGATGAAGGAGATAGTCTAATCATCGGAGATCCA
GATCCTTCTGTCAAAGTTATTCGCATGTCTAAGGAGAGATTTCAGCATGAATGGACAGGTGTAGCTATCTTCTTTTCTCC
AAAGGATGATTATCAGCCTCAAAAAGATAAAAGAAGAGGATTAACAAGTTTCATACCTTCTTTTTTAAAGCAAAAGAGTC
TCTTGTTCTATATTATAATGGCGAGTTTAATCATTACTTTAATAGAAATTATTGGAGCTTTTTATCTCCAAGTAATGCTG
GATGAGTATATTCCCAGTCAAAAAATTTCAACTTTAGGTTTTATCACTTTAGGATTGATAATAACTTATGTTGCCCAACA
AATAATAGCTTTTGCAAAAGAGTACTTATTAATTATATTAGGACAAAGGCTGGTAATTGATGTTATACTTACTTATATTA
AGCACATTTTTATTCTTCCGATGTCTTTTTTTTCGACAAGACGAACGGGAGAAATCACATCTCGCTTCACTGATGCCAAT
CAAATTATTGATGCTGTGGCGTCAACAATTTTTTCTATTTTCTTAGACATTTCGATGGTATTTATAGTTGGTGGAGTATT
ATTAATTCAAAATGTCGTTTTATTTTTCCTAGCCTTGCTCTGCGTTCCTATCTACATTATCATTGTTTTTGCATTTATGA
AAATGTTTGGTTACTTAAACTATGAGGTAATGGAAAGTAATGCGATAATGTCTTCATCTGTTATTGAGGATATTAATGGA
ATAGAAACTATCAAATCTTTGACGAGTGAAGAAGTTAGCTATCAGAGAATTGACAAGGAATTTGTTGATTTTTTAGAGAA
ATCTTTTAGGCTGCATAAGTATGGAGCTATTCAAGTCTCAATTAAAACTGCTGCAAAGCTAATTTTGAATATCGTTATTC
TATGGTATGGAGCACGATTGGTTATGACCGGGAAAATTTCAGTGGGTCAAATGATTGCTTTTAATGTGCTTTTAGGATAT
TTTTCAAGCCCAATTGAAAATATGATTAATTTACAAATTAAGCTCCAATCAGCCCGCATAGCTAATACGCGTCTCAATGA
AGTCTATCTGGTCGATTCTGAGTTTGAAAATAATGGGGAGCTTTCAGAAGGCAGCTTTTTGGATGGGGATATCTCTTTTG
AAAAGTTATCTTACAAGTATGGTTATGGTCGTGATACTCTGTCAGATATCAATCTAACTATTAAAAAAGGTTCAAAGGTC
AGTCTGGTCGGAGCCTCTGGTTCTGGTAAAACGACTCTTGCCAAGATGATTGTCAATTTTTATGAACCTATACAGGGTCT
TATCCGTCTTAATGGCTATGACCTAAAAGATATAGATAAGACTGTTTTACGCCAGCATATTAACTATCTCCCCCAACAAG
CTTATGTCTTTAGTGGTACCATTATGGATAATCTGACCTTGGGAGCCAAGAAAGACATTAATCAGGAAGATATTATTCGA
GCCTGTGAAATTGCTGAGATTCATTCAGACATTGAACAAATGCCGCTGGGGTACCAGACTGAGTTATCTGATGGTACTGG
AGTTTCCGGTGGCCAGAAGCAGCGGATTGCCTTGGCTCGCGCTCTCTTAACCCAAGCTCCAGTTTTGATTTTGGATGAGG
CCACCAGCAGTCTGGATGTCCTGACTGAAAAGAAAATCGTCAACAACCTCATGGCCATGACCAATAAGACTATTGTTTTT
GTGGCACACCGTTTGAGTATTGCTCAACGGACAGACCGAATTATTGTTATGGATCAAGGTAAGATTGTGGAAGAAGGTAG
CCATAAGGAACTTTTAGCTCATAAAGGCTTCTACTACAAGCTGTTTAACTAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (547-696)

• Peptidase C39 family (Peptidase_C39) (53-189)

• ABC transporter transmembrane region (ABC_membrane) (215-484)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	73.377	98.952	0.726
comA	Streptococcus mitis NCTC 12261	62.535	93.054	0.582
comA	Streptococcus pneumoniae Rx1	61.69	93.054	0.574
comA	Streptococcus pneumoniae D39	61.69	93.054	0.574
comA	Streptococcus pneumoniae R6	61.69	93.054	0.574
comA	Streptococcus mitis SK321	61.69	93.054	0.574
comA	Streptococcus pneumoniae TIGR4	61.408	93.054	0.571
comA	Streptococcus gordonii str. Challis substr. CH1	60.084	93.578	0.562