Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   FE005_RS00240 Genome accession   NZ_CP040461
Coordinates   49216..50523 (+) Length   435 a.a.
NCBI ID   WP_060814535.1    Uniprot ID   -
Organism   Enterococcus sp. M190262     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 44216..55523
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FE005_RS00220 (FE005_00220) - 44491..46362 (-) 1872 WP_138371094.1 beta-glucoside-specific PTS transporter subunit IIABC -
  FE005_RS00225 (FE005_00225) - 46487..47308 (+) 822 WP_103300988.1 MurR/RpiR family transcriptional regulator -
  FE005_RS00230 (FE005_00230) - 47591..48439 (-) 849 WP_138371095.1 hypothetical protein -
  FE005_RS00235 (FE005_00235) rlmH 48488..48967 (-) 480 WP_081131541.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  FE005_RS00240 (FE005_00240) htrA 49216..50523 (+) 1308 WP_060814535.1 S1C family serine protease Regulator
  FE005_RS00245 (FE005_00245) ytpR 50578..51189 (-) 612 WP_138371096.1 YtpR family tRNA-binding protein -
  FE005_RS00250 (FE005_00250) - 51401..51856 (-) 456 WP_005470736.1 universal stress protein -
  FE005_RS00255 (FE005_00255) - 51875..52189 (-) 315 WP_003125825.1 thioredoxin family protein -
  FE005_RS00260 (FE005_00260) pepA 52407..53483 (-) 1077 WP_003125824.1 glutamyl aminopeptidase -
  FE005_RS00265 (FE005_00265) - 53677..54021 (+) 345 WP_138371097.1 PepSY domain-containing protein -
  FE005_RS00270 (FE005_00270) - 54139..55182 (-) 1044 WP_138371098.1 hypothetical protein -

Sequence

Protein


Download         Length: 435 a.a.        Molecular weight: 44823.65 Da        Isoelectric Point: 4.3788

>NTDB_id=364631 FE005_RS00240 WP_060814535.1 49216..50523(+) (htrA) [Enterococcus sp. M190262]
MVRKNVTPGRKPSSGLLKKLGIGILGGVVGGLLTFGGLYLAMGSSLTSPGTTATSGVQDNNGQTKVSNVKYDVNSDVTKA
VEKVQGAVVSIINLQQNNANGLEGLFGSGQQGGQGSGTENSGDDSSLEASSEGSGVIYKVDGDKAYIVTNNHVVEGQDGL
EVVLSDGTKVKAELVGTDAYTDLAVLRISSDKVDTVASFGDSDSLKVGEPAIAIGSPLGSSFANSVTQGIVSSLNRQVTN
QNESGEAVSINAIQTDAAINPGNSGGPLINVEGQVIGINSSKIASTSESTSSVSVEGMGFAIPSNDVVDIINQLEKDGKV
VRPALGIRTINLSSITSQQQEQILKVPSSVTDGVVVYSVNNATPAEQAGLKQYDVITKIDDTDISTTTDLQSALYKHKVG
DTITVTFYRGKEEKTAKVVLSVDTSINEQSTDSSN

Nucleotide


Download         Length: 1308 bp        

>NTDB_id=364631 FE005_RS00240 WP_060814535.1 49216..50523(+) (htrA) [Enterococcus sp. M190262]
ATGGTACGAAAAAATGTGACACCAGGAAGAAAACCTTCTTCCGGTTTATTAAAAAAATTAGGTATTGGCATTCTTGGCGG
AGTAGTTGGTGGTTTGTTGACCTTCGGCGGACTTTATCTGGCGATGGGCTCTTCTTTGACTTCACCTGGAACGACTGCAA
CCAGCGGTGTTCAAGATAACAATGGACAAACGAAAGTCTCCAATGTTAAATATGATGTCAACAGCGATGTAACAAAAGCA
GTCGAAAAAGTGCAAGGAGCAGTCGTTTCGATCATCAACTTGCAACAAAATAATGCGAATGGCCTCGAAGGGTTATTTGG
CTCTGGTCAGCAAGGTGGTCAAGGATCAGGGACTGAGAATTCAGGCGATGACAGTTCACTAGAAGCTTCTTCTGAAGGAA
GTGGCGTGATTTATAAAGTAGATGGTGACAAAGCGTATATCGTTACGAATAACCACGTAGTAGAAGGACAAGATGGTTTG
GAAGTCGTTCTCTCTGATGGCACAAAAGTCAAAGCTGAATTAGTCGGAACAGACGCTTACACTGACCTTGCTGTTTTACG
CATCTCTTCTGATAAAGTAGACACGGTTGCTTCTTTCGGCGATTCTGATTCACTAAAAGTTGGCGAACCAGCAATTGCGA
TTGGTTCTCCATTAGGATCTAGCTTTGCAAATTCTGTAACGCAAGGGATTGTTTCTTCTCTGAATCGTCAAGTAACGAAC
CAAAATGAATCTGGTGAAGCAGTCAGCATCAATGCGATTCAAACAGATGCAGCGATCAACCCAGGAAACTCTGGTGGTCC
ACTGATCAACGTTGAAGGACAAGTGATCGGAATCAACTCTAGCAAGATCGCCAGCACTTCTGAATCAACATCAAGTGTCA
GCGTAGAAGGAATGGGCTTCGCGATCCCAAGTAACGACGTTGTCGATATTATCAACCAATTAGAAAAAGACGGCAAAGTT
GTTCGTCCAGCATTGGGTATTCGAACAATCAACTTAAGCTCAATCACTTCGCAACAACAAGAACAAATCTTGAAAGTACC
ATCTTCTGTCACTGACGGAGTAGTCGTATACTCAGTAAATAACGCGACACCAGCTGAACAAGCAGGATTGAAACAATACG
ATGTCATCACGAAAATCGATGATACCGACATCAGCACAACCACAGATCTACAATCTGCACTGTACAAGCACAAAGTCGGT
GATACGATCACAGTGACGTTCTACCGCGGCAAAGAAGAAAAAACAGCCAAAGTCGTTCTATCTGTAGATACTTCGATCAA
TGAACAATCGACTGACAGCAGCAACTAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(323-419)

Peptidase family M50 (Peptidase_M50)

(290-421)

Trypsin-like peptidase domain (Trypsin_2)

(133-278)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

55.528

91.494

0.508
  htrA Streptococcus gordonii str. Challis substr. CH1

50.827

97.241

0.494
  htrA Streptococcus mitis NCTC 12261

54.331

87.586

0.476
  htrA Streptococcus pneumoniae TIGR4

55.682

80.92

0.451
  htrA Streptococcus pneumoniae Rx1

55.682

80.92

0.451
  htrA Streptococcus pneumoniae D39

55.682

80.92

0.451
  htrA Streptococcus pneumoniae R6

55.682

80.92

0.451

Multiple sequence alignment