Detailed information    

insolico Bioinformatically predicted

Overview

Name   coiA   Type   Machinery gene
Locus tag   SMI_RS04945 Genome accession   NC_013853
Coordinates   935048..936001 (+) Length   317 a.a.
NCBI ID   WP_000495918.1    Uniprot ID   D3H8N2
Organism   Streptococcus mitis B6     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 930048..941001
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMI_RS04940 (smi_0979) - 931116..934772 (+) 3657 WP_000468780.1 YSIRK signal domain/LPXTG anchor domain surface protein -
  SMI_RS04945 (smi_0980) coiA 935048..936001 (+) 954 WP_000495918.1 competence protein CoiA Machinery gene
  SMI_RS04950 (smi_0981) pepF 936020..937822 (+) 1803 WP_000244106.1 oligoendopeptidase F Regulator
  SMI_RS04955 (smi_0982) - 937824..938537 (+) 714 WP_012972506.1 O-methyltransferase -
  SMI_RS04960 (smi_0983) prsA 938604..939542 (+) 939 WP_000727942.1 peptidylprolyl isomerase PrsA -
  SMI_RS04965 (smi_0984) ftsW 939703..940926 (+) 1224 WP_000703373.1 cell division peptidoglycan polymerase FtsW -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 38200.89 Da        Isoelectric Point: 9.2540

>NTDB_id=36317 SMI_RS04945 WP_000495918.1 935048..936001(+) (coiA) [Streptococcus mitis B6]
MFVARDARGQLVNVLEDRLEKQAYTCPACGGQLRLRQGPSVRTHFAHKSLKDCDFSFENESPEHLTNKEVLYQWLKKETE
VQLEHPLPELKQIADVFVNGNLALEVQCSPLSQKVLKERSEGYRSQGYQVLWLLGQKLWLKDRLTRLQQGFLYFSQNMGF
YVWELDKEKQILRLKYLIHQDLRGKLHYQIKEFPYGQASLLEILRFPYKKQKISYFTVSQDKDICRYIRQQLFYQNPIWM
KEQAEAYQKGKNLLTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYKENPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide


Download         Length: 954 bp        

>NTDB_id=36317 SMI_RS04945 WP_000495918.1 935048..936001(+) (coiA) [Streptococcus mitis B6]
ATGTTTGTTGCGAGAGATGCTAGGGGACAGTTGGTAAATGTGTTAGAGGATAGGCTCGAGAAACAAGCATATACCTGCCC
CGCTTGTGGAGGTCAGCTCCGTTTGCGTCAAGGACCAAGTGTACGGACCCATTTTGCCCATAAATCTTTAAAAGACTGTG
ATTTTTCATTTGAAAATGAAAGCCCAGAACACTTGACAAATAAGGAAGTCCTCTATCAGTGGTTGAAAAAAGAGACAGAG
GTACAATTAGAACATCCCCTTCCAGAGCTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTGGCTTTAGAGGTTCA
GTGTAGCCCCTTGTCTCAAAAAGTTCTTAAAGAGCGCAGTGAGGGCTATCGTAGTCAGGGTTACCAAGTACTGTGGTTAC
TGGGTCAAAAACTGTGGCTCAAGGACCGTTTGACTCGTCTGCAACAAGGTTTTCTCTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAAGAAAAACAGATTTTAAGGCTCAAATACCTAATCCACCAAGACCTCCGTGGTAAACTCCA
TTATCAGATTAAGGAATTTCCCTATGGTCAAGCTAGTTTATTGGAAATATTGCGTTTTCCTTATAAGAAACAAAAAATAT
CTTATTTTACAGTTTCTCAGGACAAGGACATTTGTCGCTATATCCGGCAACAACTGTTTTATCAAAATCCCATTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAAAAAATCTCCTAACTTATGGACTAAAAGAATGGTATCCACAAATTCGGCC
AATAGTAGGCAAATTTTTCCAGATTGAGCAAGATTTGACCAGCTATTATCAGCACTTTTACACCTATTACAAAGAAAATC
CTCAAAATGATTGGCAAAAGCTCTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAA

Domains

Predicted by InterproScan.

Competence protein CoiA-like family (CoiA_nuc)

(8-256)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB D3H8N2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  coiA Streptococcus pneumoniae TIGR4

91.483

100

0.915
  coiA Streptococcus pneumoniae Rx1

91.483

100

0.915
  coiA Streptococcus pneumoniae D39

91.483

100

0.915
  coiA Streptococcus pneumoniae R6

91.483

100

0.915
  coiA Streptococcus mitis NCTC 12261

89.905

100

0.899
  coiA Lactococcus lactis subsp. cremoris KW2

43.168

100

0.438

Multiple sequence alignment