Detailed information    

insolico Bioinformatically predicted

Overview


Name   comW   Type   Regulator
Locus tag   SMI_RS00105 Genome accession   NC_013853
Coordinates   22057..22293 (+) Length   78 a.a.
NCBI ID   WP_000941921.1    Uniprot ID   D3H631
Organism   Streptococcus mitis B6     
Function   stabilization and activation of ComX (predicted from homology)   
Competence regulation

Genomic Context


Location: 17057..27293
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMI_RS00105 (smi_0021) comW 22057..22293 (+) 237 WP_000941921.1 sigma(X)-activator ComW Regulator
  SMI_RS00110 (smi_0022) - 22524..23810 (+) 1287 WP_012972411.1 adenylosuccinate synthase -
  SMI_RS00115 (smi_0024) tadA 24011..24478 (+) 468 WP_000386764.1 tRNA adenosine(34) deaminase TadA -
  SMI_RS00125 (smi_0026) - 24665..25108 (+) 444 WP_000701987.1 dUTP diphosphatase -
  SMI_RS00130 (smi_0027) - 25110..25649 (+) 540 WP_000691251.1 histidine phosphatase family protein -
  SMI_RS00135 (smi_0028) radA 25663..27024 (+) 1362 WP_164925536.1 DNA repair protein RadA Machinery gene

Sequence


Protein


Download         Length: 78 a.a.        Molecular weight: 9935.56 Da        Isoelectric Point: 7.2695

>NTDB_id=36279 SMI_RS00105 WP_000941921.1 22057..22293(+) (comW) [Streptococcus mitis B6]
MLQSIYDQMMDFYRNIEEEYGMFFGDNFDWEHVHFKFLIYYLVRYRIVSRRDFIVYHYRVAYRLYLEKLIMKQGFVAC

Nucleotide


Download         Length: 237 bp        

>NTDB_id=36279 SMI_RS00105 WP_000941921.1 22057..22293(+) (comW) [Streptococcus mitis B6]
ATGCTACAAAGTATTTATGATCAGATGATGGATTTTTATAGAAATATTGAAGAAGAGTATGGTATGTTCTTCGGTGATAA
TTTTGATTGGGAACATGTTCATTTTAAGTTTTTGATTTATTATCTTGTCCGATATCGTATTGTGAGTCGTCGGGATTTTA
TTGTTTACCATTATCGTGTTGCTTATCGTTTGTATCTTGAAAAATTGATAATGAAACAAGGTTTTGTTGCTTGTTGA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB D3H631

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comW Streptococcus mitis SK321

97.436

100

0.974

  comW Streptococcus mitis NCTC 12261

97.403

98.718

0.962

  comW Streptococcus pneumoniae Rx1

78.205

100

0.782

  comW Streptococcus pneumoniae D39

78.205

100

0.782

  comW Streptococcus pneumoniae R6

78.205

100

0.782

  comW Streptococcus pneumoniae TIGR4

78.205

100

0.782


Multiple sequence alignment