Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   FD735_RS07695 Genome accession   NZ_CP040231
Coordinates   1461346..1463247 (-) Length   633 a.a.
NCBI ID   WP_139658886.1    Uniprot ID   A0A5B7YA72
Organism   Streptococcus sp. 1643     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1456346..1468247
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FD735_RS07670 (FD735_07670) - 1456479..1457444 (+) 966 WP_139658883.1 LacI family DNA-binding transcriptional regulator -
  FD735_RS07675 (FD735_07675) - 1457479..1458753 (-) 1275 WP_139658884.1 hydroxymethylglutaryl-CoA reductase, degradative -
  FD735_RS07680 (FD735_07680) - 1458753..1459925 (-) 1173 WP_139659115.1 hydroxymethylglutaryl-CoA synthase -
  FD735_RS07685 (FD735_07685) - 1460044..1460499 (-) 456 WP_000176909.1 threonine/serine exporter family protein -
  FD735_RS07690 (FD735_07690) - 1460501..1461259 (-) 759 WP_139658885.1 threonine/serine exporter family protein -
  FD735_RS07695 (FD735_07695) stkP 1461346..1463247 (-) 1902 WP_139658886.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  FD735_RS07700 (FD735_07700) - 1463244..1463984 (-) 741 WP_139658887.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  FD735_RS07705 (FD735_07705) rsmB 1464000..1465313 (-) 1314 WP_061428025.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  FD735_RS07710 (FD735_07710) fmt 1465306..1466241 (-) 936 WP_139658888.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 633 a.a.        Molecular weight: 68914.23 Da        Isoelectric Point: 8.9717

>NTDB_id=362657 FD735_RS07695 WP_139658886.1 1461346..1463247(-) (stkP) [Streptococcus sp. 1643]
MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIG
EEDGQQYLAMEYVAGLDLKRYIKEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATFQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSVIAENPSVP
QALENVVIKATAKKLSDRYQSVSEMYVDLSTSLSYNRRNEPKLVFDDASKADTKTLPKVPQSTLTSIPKAPAQEERPQPK
KPTQPVAEPVPAPKPAKKRKFKARYMILLASLLLVAASLIWILSRTPATIPIPDVAGQTVAEAKEALKKSKFEAGEEKSE
ASDTVAEGRVIRTDPEAGSGRKEGTKVNLIVSSGKQSFQLSNYVGRKYTEVVAELKEKKVPENLIKMEEEESSESEPGTI
LRQTPASGSTYDLSKATTITLTVAKKVTSVSMPNYVGSSLEFTKNNLTQIVGVKEANIEVVEVSTAPEGTAEGTVVSQTP
RAGELVDLASTRIKLSIYKPKTPPSTSSSNPAQRGNQGSPTSPNQGNQQGNQQGHTPSSSSSNNEGSHESSRD

Nucleotide


Download         Length: 1902 bp        

>NTDB_id=362657 FD735_RS07695 WP_139658886.1 1461346..1463247(-) (stkP) [Streptococcus sp. 1643]
ATGATCCAAATCGGCAAGATTTTTGCCGGGCGGTATCGGATTGTCAAGCAGATTGGTCGAGGAGGCATGGCAGATGTTTA
CTTGGCCAAGGATTTGATCCTAGACGGGGAAGAAGTGGCAGTGAAGGTCCTGAGGACCAACTACCAGACAGACCCTATTG
CTGTGGCACGTTTCCAACGTGAAGCGAGAGCCATGGCGGATCTGGACCATCCTCATATCGTTCGGATAACAGATATTGGT
GAGGAAGATGGTCAACAGTACCTAGCTATGGAATACGTAGCAGGTCTTGACCTCAAGCGTTATATCAAAGAACACTATCC
TCTTTCAAACGAAGAAGCAGTTCGAATTATGGGACAAATCCTCTTGGCCATGCGCTTAGCCCATACTCGAGGAATTGTTC
ACCGGGATTTGAAACCTCAAAATATCCTCTTGACACCTGACGGCACAGCCAAGGTCACGGACTTTGGGATTGCCGTAGCC
TTTGCAGAGACCAGTCTGACCCAGACAAACTCAATGTTAGGCTCTGTTCATTATTTGTCACCTGAACAAGCGCGTGGTTC
TAAAGCGACCTTCCAGAGTGATATCTATGCAATGGGGATCATCTTCTATGAAATGCTGACGGGACATATCCCTTATGATG
GGGATAGTGCAGTTACGATTGCCCTCCAGCATTTCCAGAAGCCACTTCCGTCCGTCATAGCTGAAAACCCATCTGTCCCT
CAGGCTTTAGAAAATGTTGTCATCAAGGCGACTGCTAAGAAGCTGTCAGACCGTTATCAGTCTGTTTCAGAAATGTATGT
GGACTTGTCAACTAGCTTGTCTTATAATCGTCGCAATGAACCGAAGCTGGTCTTTGATGATGCGAGTAAGGCAGACACTA
AGACTTTGCCTAAAGTTCCACAAAGTACACTGACATCGATTCCTAAAGCTCCGGCGCAGGAAGAACGCCCTCAACCAAAG
AAACCGACTCAACCAGTGGCAGAACCGGTTCCAGCGCCAAAGCCAGCTAAGAAACGGAAATTTAAGGCTCGCTATATGAT
TCTTTTGGCCAGTCTTCTATTGGTTGCGGCCTCTTTAATCTGGATTTTGTCTAGAACACCTGCAACGATTCCCATTCCTG
ATGTGGCTGGACAAACCGTTGCAGAGGCCAAAGAAGCACTCAAAAAATCCAAGTTTGAAGCTGGTGAAGAGAAATCGGAG
GCTAGCGATACAGTAGCGGAAGGACGCGTTATTCGAACGGATCCAGAAGCTGGTAGTGGCCGAAAAGAAGGAACCAAGGT
CAATTTGATTGTTTCTTCTGGTAAGCAATCCTTCCAATTGAGCAATTACGTCGGACGCAAGTATACGGAAGTCGTAGCTG
AACTCAAGGAGAAGAAGGTTCCTGAAAATCTAATCAAGATGGAAGAGGAAGAATCCAGCGAAAGTGAACCTGGAACCATC
CTTAGACAGACTCCTGCTTCGGGTTCGACTTATGATCTCTCAAAAGCTACTACGATTACCTTAACAGTAGCTAAGAAGGT
GACTAGTGTCAGCATGCCGAACTACGTCGGTTCAAGCCTCGAGTTTACAAAGAATAACTTGACTCAGATTGTCGGTGTGA
AGGAAGCAAATATTGAGGTTGTTGAAGTATCGACTGCTCCTGAAGGAACGGCAGAAGGAACTGTTGTAAGTCAAACGCCA
AGAGCAGGAGAACTGGTTGATCTTGCAAGTACGCGTATCAAACTTTCCATCTACAAACCAAAAACACCACCGTCAACTTC
ATCCTCTAATCCTGCCCAACGTGGGAACCAGGGTTCTCCTACAAGTCCAAACCAGGGGAACCAACAAGGAAATCAACAAG
GGCACACTCCTTCTAGCAGTTCATCCAATAATGAAGGATCTCACGAAAGTTCCCGAGATTAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(441-505)

PASTA domain (PASTA)

(372-432)

PASTA domain (PASTA)

(510-579)

Protein kinase domain (Pkinase)

(12-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A5B7YA72

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

78.328

92.575

0.725
  stkP Streptococcus pneumoniae D39

77.986

92.575

0.722
  stkP Streptococcus pneumoniae R6

77.986

92.575

0.722
  stkP Streptococcus pneumoniae Rx1

77.816

92.575

0.72
  pknB Streptococcus mutans UA159

56.153

91.153

0.512
  stkP/pknB Streptococcus salivarius strain HSISS4

52.277

93.681

0.49

Multiple sequence alignment