Detailed information    

insolico Bioinformatically predicted

Overview

Name   coiA   Type   Machinery gene
Locus tag   FD735_RS04050 Genome accession   NZ_CP040231
Coordinates   746060..747016 (+) Length   318 a.a.
NCBI ID   WP_139658550.1    Uniprot ID   A0A5B7Y589
Organism   Streptococcus sp. 1643     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 741060..752016
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FD735_RS04035 (FD735_04035) smpB 743307..743774 (+) 468 WP_139658549.1 SsrA-binding protein SmpB -
  FD735_RS04040 (FD735_04040) tehB 743789..744649 (+) 861 WP_000413060.1 SAM-dependent methyltransferase TehB -
  FD735_RS04045 (FD735_04045) - 744836..745984 (+) 1149 WP_125391064.1 DUF1887 family protein -
  FD735_RS04050 (FD735_04050) coiA 746060..747016 (+) 957 WP_139658550.1 competence protein CoiA Machinery gene
  FD735_RS04055 (FD735_04055) pepF 747035..748837 (+) 1803 WP_139658551.1 oligoendopeptidase F Regulator
  FD735_RS04060 (FD735_04060) - 748839..749552 (+) 714 WP_139658552.1 O-methyltransferase -
  FD735_RS10020 - 749601..749855 (+) 255 WP_369689503.1 recombinase family protein -
  FD735_RS10025 - 749810..749926 (+) 117 WP_369689506.1 recombinase family protein -
  FD735_RS10030 - 749948..750223 (+) 276 WP_369689504.1 hypothetical protein -

Sequence

Protein


Download         Length: 318 a.a.        Molecular weight: 37854.32 Da        Isoelectric Point: 9.2634

>NTDB_id=362643 FD735_RS04050 WP_139658550.1 746060..747016(+) (coiA) [Streptococcus sp. 1643]
MFVARDAKGNLVNALEKDVTKQAYTCPACGGGLRLRQGQSIRTHFAHERLRDCIAIFENESPEHLGNKEALYHWAKKDNQ
VALEYSLPEIQQIADVLVNEKLALEVQCSPLSQKLLGDRSQGYRSQGYQVIWLLGEKLWLKERLTQLQRGFLYFSQNMGF
YVWELDIKKQVLRLKYLLHQDLRGKLHFQVKEFPYGQGNLLEILRFPYQKQKLPRFAVVQDSTICHYIRQQLYYQTPYWM
KKQEEAYYQGDNLLKHQLDDWYPQVRPIESGDFLQIETDLDSYYRNFQAYYQKNPKNNRQKLYPPAFYHLYFSKNVVK

Nucleotide


Download         Length: 957 bp        

>NTDB_id=362643 FD735_RS04050 WP_139658550.1 746060..747016(+) (coiA) [Streptococcus sp. 1643]
ATGTTTGTAGCCAGAGATGCCAAGGGGAATTTGGTGAATGCCCTTGAAAAAGATGTGACCAAGCAAGCTTATACTTGTCC
AGCCTGTGGGGGCGGACTACGATTACGTCAAGGACAGAGTATTCGAACGCACTTTGCCCATGAAAGGTTAAGAGATTGTA
TTGCCATTTTTGAAAATGAAAGTCCAGAACACTTAGGCAACAAAGAGGCCCTTTATCATTGGGCCAAGAAGGACAATCAG
GTCGCCTTAGAATATAGTCTGCCCGAGATTCAGCAGATAGCAGATGTTCTCGTCAATGAGAAACTAGCTCTGGAGGTTCA
GTGCAGTCCCTTGTCTCAAAAGCTTTTAGGCGATAGAAGTCAAGGATACCGCAGCCAGGGCTATCAGGTTATCTGGCTAC
TGGGAGAAAAACTCTGGTTAAAAGAGCGATTAACACAATTGCAAAGGGGATTTCTCTATTTTAGTCAAAATATGGGATTT
TATGTTTGGGAACTGGATATCAAAAAGCAAGTTTTGAGACTCAAATATCTTTTGCATCAGGACCTACGTGGCAAGCTTCA
TTTTCAGGTCAAGGAATTTCCCTATGGCCAAGGAAATCTCTTGGAAATTCTACGATTTCCTTATCAAAAACAAAAACTGC
CTCGTTTTGCTGTTGTGCAAGATTCAACTATCTGTCACTACATTCGCCAGCAGTTGTACTATCAAACGCCCTACTGGATG
AAGAAGCAGGAGGAAGCTTATTATCAAGGAGACAATCTATTAAAGCATCAACTGGACGACTGGTATCCCCAGGTCAGACC
GATAGAATCGGGTGATTTTTTGCAGATTGAAACGGATTTGGATAGCTATTATAGAAATTTTCAGGCTTACTATCAAAAAA
ATCCGAAAAATAATCGCCAAAAGCTCTATCCACCAGCCTTTTATCACTTATATTTCTCAAAAAATGTGGTAAAATAG

Domains

Predicted by InterproScan.

Competence protein CoiA-like family (CoiA_nuc)

(12-249)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A5B7Y589

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  coiA Streptococcus mitis NCTC 12261

71.384

100

0.714
  coiA Streptococcus pneumoniae Rx1

71.069

100

0.711
  coiA Streptococcus pneumoniae D39

71.069

100

0.711
  coiA Streptococcus pneumoniae R6

71.069

100

0.711
  coiA Streptococcus pneumoniae TIGR4

70.755

100

0.708
  coiA Lactococcus lactis subsp. cremoris KW2

41.846

100

0.428

Multiple sequence alignment