Detailed information    

insolico Bioinformatically predicted

Overview

Name   pknB   Type   Regulator
Locus tag   GALLO_RS02725 Genome accession   NC_013798
Coordinates   517983..519860 (+) Length   625 a.a.
NCBI ID   WP_012961536.1    Uniprot ID   -
Organism   Streptococcus gallolyticus UCN34     
Function   modulate the activity of ComDE; modulate the activity of VicKR (predicted from homology)   
Competence regulation

Genomic Context

Location: 512983..524860
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GALLO_RS02710 (GALLO_0491) fmt 514961..515896 (+) 936 WP_012961534.1 methionyl-tRNA formyltransferase -
  GALLO_RS02715 (GALLO_0492) rsmB 515886..517208 (+) 1323 WP_012961535.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  GALLO_RS02720 (GALLO_0493) - 517246..517983 (+) 738 WP_009853567.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  GALLO_RS02725 (GALLO_0494) pknB 517983..519860 (+) 1878 WP_012961536.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  GALLO_RS02730 (GALLO_0495) liaF 519971..520666 (+) 696 WP_012961537.1 cell wall-active antibiotics response protein LiaF -
  GALLO_RS02735 (GALLO_0496) - 520663..521688 (+) 1026 WP_012961538.1 sensor histidine kinase -
  GALLO_RS02740 (GALLO_0497) - 521672..522316 (+) 645 WP_009853571.1 response regulator transcription factor -
  GALLO_RS02745 (GALLO_0498) - 522435..523835 (+) 1401 WP_012961539.1 Cof-type HAD-IIB family hydrolase -
  GALLO_RS02750 (GALLO_0499) - 523835..524191 (+) 357 WP_003063541.1 S1 RNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 625 a.a.        Molecular weight: 67656.85 Da        Isoelectric Point: 5.0759

>NTDB_id=36182 GALLO_RS02725 WP_012961536.1 517983..519860(+) (pknB) [Streptococcus gallolyticus UCN34]
MIQIGKLFAGRYRILKSIGRGGMADVYLAKDLILDNEEVAIKVLRTNYQTDQIAVARFQREARAMAELNHPNIVSIRDIG
EEDGQQFLVMEYVDGSDLKKYIQDHAPLSNNEVVRIMEEVLSAMTLAHQQGIVHRDLKPQNILLTKDGTVKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKPLPSIIDENKNVP
QALENVVIKATAKRLSDRYASTFEMSRDLMTALSYNRSREPKLVFEDTENTKTLPKVTTSTSVPSTTEQLLKKQKAAKED
KAATENKATKAKTKKKKSRRMFGTLMKIFFAVVIVAIAIFTYLTLTSPSTVSVPDVAGSSLSEAKTTIKSSGLKVGTVHK
VSSDTVESGYVIKTSPTAGSSKKEGSSIDIYVSKGSSGFKIKDYTGQDYQTAVKDLVNNYGVSESQIEIEEVSTSDYDEG
VIISQTPSEGETFKVSGDDKITFKVAAESTVTMPNLTGYTYSEAIAALTALGVSSSHITVYQADPNSSTGYVQVSSPSST
ATVTAQTPYYGETLSGNVVLYLAADEEESSQAPSSSSSESSESKESSSSSSSTDDSSSSTETSDE

Nucleotide


Download         Length: 1878 bp        

>NTDB_id=36182 GALLO_RS02725 WP_012961536.1 517983..519860(+) (pknB) [Streptococcus gallolyticus UCN34]
ATGATTCAGATTGGCAAATTATTTGCTGGTCGTTATCGGATCCTCAAATCTATCGGACGGGGTGGAATGGCAGATGTTTA
TCTGGCAAAAGATCTCATTCTTGATAATGAAGAAGTTGCCATTAAGGTGCTTCGGACGAATTATCAGACTGATCAAATTG
CCGTAGCGCGTTTCCAACGGGAAGCGCGTGCCATGGCAGAACTGAACCATCCAAATATCGTCTCGATTCGTGATATTGGA
GAAGAAGACGGACAGCAATTCTTAGTAATGGAATATGTTGATGGCTCGGACTTGAAAAAATACATTCAAGATCATGCTCC
GCTTTCTAATAATGAAGTTGTTAGAATCATGGAAGAAGTCTTATCTGCGATGACTTTGGCGCATCAACAAGGAATTGTTC
ACCGTGATTTAAAACCACAAAATATCTTATTAACCAAAGACGGAACTGTTAAAGTTACTGACTTTGGTATCGCCGTAGCC
TTTGCTGAAACAAGTTTAACGCAAACCAATTCAATGCTAGGTAGTGTGCATTATTTATCGCCTGAACAAGCACGTGGTTC
AAAAGCGACTGTTCAAAGTGATATTTACGCTATGGGGATTATGTTGTTTGAAATGTTAACAGGTCACATCCCATATGATG
GCGATTCAGCTGTTACCATTGCGCTTCAACATTTCCAAAAACCACTTCCTTCCATCATTGATGAGAATAAAAATGTGCCA
CAAGCACTAGAAAATGTTGTTATCAAGGCGACTGCAAAACGTTTAAGTGACCGTTATGCGTCAACTTTTGAAATGAGTCG
TGATTTGATGACGGCACTTTCTTACAACCGTAGCCGTGAACCTAAACTTGTTTTTGAAGATACTGAAAATACAAAGACAC
TTCCAAAGGTAACAACATCAACATCTGTTCCTTCAACGACAGAACAACTCTTGAAGAAACAAAAAGCAGCTAAAGAAGAT
AAAGCAGCAACAGAAAACAAAGCGACTAAGGCTAAAACAAAGAAGAAAAAATCACGTCGTATGTTCGGCACGTTAATGAA
AATCTTTTTTGCAGTTGTGATTGTAGCTATTGCTATCTTTACTTACTTGACGTTGACCTCACCATCAACCGTGAGTGTTC
CAGATGTTGCTGGCTCTAGTTTATCAGAAGCAAAAACAACGATAAAATCATCAGGTCTTAAAGTTGGAACCGTTCATAAA
GTATCAAGTGATACCGTTGAGAGTGGTTATGTTATTAAGACAAGTCCAACTGCTGGTTCATCGAAAAAAGAAGGGTCATC
AATTGATATTTACGTATCAAAAGGCTCATCAGGCTTCAAGATAAAAGACTACACAGGTCAAGATTATCAAACAGCCGTTA
AAGATTTGGTTAATAATTATGGTGTTTCAGAGTCGCAAATTGAGATTGAAGAAGTCTCAACGTCAGACTATGACGAAGGT
GTTATCATTAGTCAAACGCCTAGCGAAGGTGAAACCTTTAAGGTAAGTGGCGATGATAAGATTACCTTTAAAGTAGCCGC
AGAAAGCACAGTAACAATGCCAAATCTGACAGGCTATACTTATTCAGAAGCTATTGCTGCCTTGACGGCTCTAGGTGTGT
CAAGTTCACATATTACGGTTTATCAAGCCGACCCAAATTCTTCTACGGGTTATGTGCAAGTAAGCTCACCATCTTCAACA
GCAACTGTCACTGCTCAGACACCTTATTATGGTGAAACGTTAAGTGGTAACGTGGTACTTTATCTAGCAGCTGATGAAGA
AGAAAGCTCACAGGCACCATCGTCATCAAGCTCAGAATCCTCTGAATCAAAAGAATCAAGTTCATCAAGCAGTAGTACAG
ATGACAGTAGCTCATCGACAGAAACAAGTGATGAATAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(371-434)

PASTA domain (PASTA)

(440-505)

PASTA domain (PASTA)

(511-575)

Protein kinase domain (Pkinase)

(12-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pknB Streptococcus mutans UA159

68.313

93.92

0.642
  stkP/pknB Streptococcus salivarius strain HSISS4

65.025

94.24

0.613
  stkP Streptococcus pneumoniae TIGR4

54.795

93.44

0.512
  stkP Streptococcus pneumoniae D39

54.623

93.44

0.51
  stkP Streptococcus pneumoniae R6

54.623

93.44

0.51
  stkP Streptococcus pneumoniae Rx1

54.452

93.44

0.509

Multiple sequence alignment