Detailed information    

insolico Bioinformatically predicted

Overview

Name   dsbA1   Type   Machinery gene
Locus tag   FAH67_RS00720 Genome accession   NZ_CP039886
Coordinates   130723..131364 (-) Length   213 a.a.
NCBI ID   WP_003682051.1    Uniprot ID   C0EQK7
Organism   Neisseria flavescens strain ATCC 13120     
Function   DNA binding and uptake; interact with PilQ (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 116545..129775 130723..131364 flank 948


Gene organization within MGE regions


Location: 116545..131364
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FAH67_RS00640 (FAH67_00640) - 116545..116844 (+) 300 WP_003680004.1 hypothetical protein -
  FAH67_RS11655 - 116963..117089 (+) 127 Protein_123 IS5/IS1182 family transposase -
  FAH67_RS00645 (FAH67_00645) - 117383..118573 (+) 1191 WP_003680002.1 efflux RND transporter periplasmic adaptor subunit -
  FAH67_RS00650 (FAH67_00650) - 118675..120201 (+) 1527 WP_003680001.1 DHA2 family efflux MFS transporter permease subunit -
  FAH67_RS11660 - 120346..120609 (+) 264 WP_208648187.1 transposase -
  FAH67_RS11665 - 120627..121109 (+) 483 WP_112890680.1 IS5 family transposase -
  FAH67_RS00660 (FAH67_00660) - 121229..121633 (+) 405 WP_003682599.1 hypothetical protein -
  FAH67_RS00670 (FAH67_00670) thrB 121815..122732 (-) 918 WP_003682602.1 homoserine kinase -
  FAH67_RS00705 (FAH67_00705) comE 128810..129097 (+) 288 WP_039863774.1 helix-hairpin-helix domain-containing protein Machinery gene
  FAH67_RS00710 (FAH67_00710) comP 129362..129775 (+) 414 WP_341869382.1 type IV pilin protein Machinery gene
  FAH67_RS00715 (FAH67_00715) - 129854..130678 (-) 825 WP_003682048.1 undecaprenyl-diphosphate phosphatase -
  FAH67_RS00720 (FAH67_00720) dsbA1 130723..131364 (-) 642 WP_003682051.1 thiol:disulfide interchange protein DsbA/DsbL Machinery gene

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23723.55 Da        Isoelectric Point: 9.9901

>NTDB_id=360881 FAH67_RS00720 WP_003682051.1 130723..131364(-) (dsbA1) [Neisseria flavescens strain ATCC 13120]
MKQRIKQTIAALSLSLLSLIAQAATEGVDYTVLSRPIPQQQAGKIEVLEFFGYFCVHCYHLDPVLLQHSKTFAKDVSLRT
EHVVWMPEMLGLAKVAAAVNLSGLKYQANPVIFKAVYEQKINLADTNAFRSWVGKQTGFDSKKLLQTYNSPAAASAAAKM
QQLTETYRIENTPTVIVGGKYKVNFNGTDWKAGMKTIDELIVKVRREQSSKPL

Nucleotide


Download         Length: 642 bp        

>NTDB_id=360881 FAH67_RS00720 WP_003682051.1 130723..131364(-) (dsbA1) [Neisseria flavescens strain ATCC 13120]
ATGAAGCAGCGTATAAAACAAACCATTGCCGCACTCAGCCTGAGCCTGCTCAGCCTGATTGCGCAAGCTGCTACCGAGGG
CGTGGACTATACTGTCCTCAGTCGTCCTATCCCGCAGCAACAAGCCGGAAAAATTGAAGTACTTGAGTTTTTCGGCTACT
TCTGCGTTCATTGCTACCATCTCGATCCTGTTTTGTTGCAACACAGTAAAACCTTCGCTAAAGATGTTTCCTTACGAACA
GAACACGTCGTTTGGATGCCTGAAATGTTGGGCTTGGCCAAGGTTGCCGCAGCCGTCAATCTTTCAGGTTTGAAATATCA
AGCCAATCCAGTCATCTTCAAAGCAGTTTATGAACAAAAAATCAACCTGGCCGATACCAATGCATTCCGATCATGGGTGG
GTAAACAGACGGGTTTTGACAGTAAAAAACTGCTTCAAACCTACAACAGTCCTGCTGCCGCATCGGCTGCTGCAAAAATG
CAGCAATTGACGGAAACTTATCGAATTGAAAACACACCAACTGTCATCGTCGGTGGTAAATACAAAGTCAATTTCAACGG
TACCGACTGGAAAGCCGGTATGAAAACCATAGACGAGCTCATCGTCAAAGTCCGCCGCGAACAATCCTCAAAACCACTTT
AA

Domains

Predicted by InterproScan.

Thioredoxin (Thioredoxin_4)

(44-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB C0EQK7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dsbA1 Neisseria meningitidis MC58

58.824

87.793

0.516
  dsbA2 Neisseria meningitidis MC58

58.696

86.385

0.507

Multiple sequence alignment