Detailed information NTG0035912

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: LLKF_RS09705
• Genome accession: NC_013656
• Coordinates: 2007539..2009749 (-)
• Length: 736 a.a.
• NCBI ID: WP_012898341.1
• Uniprot ID: -
• Organism: Lactococcus lactis subsp. lactis KF147
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2002539..2014749

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LLKF_RS09675 (LLKF_1938)	atpA	2002581..2004083 (-)	1503	WP_004255265.1	F0F1 ATP synthase subunit alpha	-
LLKF_RS09680 (LLKF_1939)	-	2004270..2004797 (-)	528	WP_012898339.1	F0F1 ATP synthase subunit delta	-
LLKF_RS09685 (LLKF_1940)	atpF	2004799..2005305 (-)	507	WP_010906128.1	F0F1 ATP synthase subunit B	-
LLKF_RS09690 (LLKF_1941)	atpB	2005320..2006033 (-)	714	WP_004255255.1	F0F1 ATP synthase subunit A	-
LLKF_RS09695 (LLKF_1942)	-	2006078..2006293 (-)	216	WP_004255250.1	F0F1 ATP synthase subunit C	-
LLKF_RS09700 (LLKF_1943)	-	2006478..2007254 (-)	777	WP_012898340.1	alpha/beta hydrolase	-
LLKF_RS09705 (LLKF_1944)	comEC	2007539..2009749 (-)	2211	WP_012898341.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
LLKF_RS09710 (LLKF_1945)	comEA	2009730..2010377 (-)	648	WP_012898342.1	ComEA family DNA-binding protein	Machinery gene
LLKF_RS09715 (LLKF_1946)	-	2010437..2011798 (-)	1362	WP_012898343.1	ABC transporter permease	-
LLKF_RS09720 (LLKF_1947)	-	2011795..2012727 (-)	933	WP_004255238.1	ABC transporter ATP-binding protein	-
LLKF_RS09725 (LLKF_1948)	-	2012832..2013230 (-)	399	WP_004255236.1	hypothetical protein	-
LLKF_RS09730 (LLKF_1949)	-	2013339..2013902 (-)	564	WP_012898344.1	GNAT family N-acetyltransferase	-

Sequence

Protein

• Length: 736 a.a.
• Molecular weight: 84661.33 Da
• Isoelectric Point: 9.6248

>NTDB_id=35912 LLKF_RS09705 WP_012898341.1 2007539..2009749(-) (comEC) [Lactococcus lactis subsp. lactis KF147]
MSCVLNKIPLIFLAYLSVILYFLIFNFNLICLILFIFSSLLALYRKYYLVIPFLLVMGSFFLVVKMDTIKNSENQPTTLS
KITMIPDTIQVNGDLLSFQGKERGQNYQVYETLKSKKEQKFYQNLSQNCQLSFTGNLQIPEKQRNFNGFDNQKYLASQNI
YRQITIDKINKIVLNDTFDLHVLRRKAIVWSQTHFPKPMNDYMTGLLFGFLSKDFNQMGDIYSSLGIIHLFALSGMQVNF
FIDWFRRIILRLGITREKLNIWQIPFSIFYAFMTGFSVSVLRALFQKNIRLNPLDNLAVTTFLLMIVSPKFLLTTGGQLT
LFYAFVISMINHKFSELKEIRKLLTESSVISLSVLPLLILDFHIFQPFSILLTIGFGFLFDVILLPLLLGTFLLSLIGYN
FNINHIFQILEWLIHEVDLPLHYPLVLGNPRPIELLILFFLIGLLIDNLFKKRRQIIFAGLIVCSFFICKNPVYPSITAV
DIGQGDSIFLQDKFNKKTILIDTGGRLALPQESWQKPQSQTNAEKTLIPYLESVGVSQIDQLILTHTDADHVGDFLNLAD
KIKIKEIWVSPGELTNNHFVEKLKKANIAIHISKVGDEIPIFDSALQVLSNGYTGKGDNNDSIVTYGNFYHTKFLFTGDL
EQEGEKELLKNYPKLKVDVLKVGHHGSKTSSNPDFIKEINPKLALISVGKENRYGHPNQETLETFKKYQIRILRTDQKGA
LKLMQINQQWRIQTVR

Nucleotide

• Length: 2211 bp

>NTDB_id=35912 LLKF_RS09705 WP_012898341.1 2007539..2009749(-) (comEC) [Lactococcus lactis subsp. lactis KF147]
ATGAGTTGTGTTTTGAATAAAATTCCTTTGATATTTTTAGCTTATCTTTCTGTTATCTTGTATTTTTTAATCTTCAATTT
TAATTTAATTTGTCTCATTTTGTTCATTTTTTCAAGTTTACTTGCCTTATATAGAAAATATTATTTAGTCATCCCATTTT
TATTAGTTATGGGAAGTTTTTTCTTAGTAGTAAAAATGGATACGATTAAGAATAGTGAAAATCAGCCAACCACTCTTTCC
AAAATTACAATGATCCCCGACACTATCCAAGTTAATGGTGATTTACTAAGTTTTCAAGGAAAAGAAAGAGGCCAAAATTA
TCAAGTTTACGAGACTCTAAAAAGTAAAAAAGAACAAAAATTTTATCAAAATCTAAGTCAAAATTGTCAGCTGAGTTTCA
CAGGAAACCTTCAAATTCCAGAAAAACAAAGAAATTTTAATGGATTCGATAATCAAAAGTATTTAGCGAGCCAGAATATT
TATCGGCAAATTACGATTGATAAAATTAATAAAATAGTTTTAAACGACACTTTTGACCTCCATGTTTTAAGACGAAAAGC
AATTGTCTGGTCACAAACTCATTTTCCAAAACCAATGAATGATTATATGACTGGCTTACTTTTTGGCTTTTTAAGTAAAG
ATTTTAATCAAATGGGAGACATTTACAGTTCATTAGGAATTATTCATCTTTTTGCCTTATCGGGAATGCAAGTTAATTTT
TTCATTGATTGGTTTCGTAGAATTATTCTTCGACTAGGAATAACGAGAGAAAAATTAAATATTTGGCAAATTCCCTTTTC
AATTTTTTATGCATTTATGACAGGATTTTCGGTTTCAGTATTACGAGCTTTATTTCAAAAAAATATTCGTCTAAATCCGT
TAGATAACCTAGCAGTGACAACCTTTCTTCTGATGATTGTCAGTCCTAAATTTTTACTGACAACAGGAGGACAACTAACT
TTATTTTATGCTTTTGTCATTTCAATGATTAATCATAAATTTTCAGAACTAAAAGAAATAAGAAAATTACTGACAGAATC
ATCAGTGATTTCTTTGAGTGTTTTACCTTTACTCATTTTGGATTTTCATATCTTTCAGCCTTTTTCAATTTTACTGACGA
TTGGCTTTGGCTTTTTATTTGATGTAATCTTATTGCCTTTACTATTAGGAACTTTTCTCTTGTCTCTAATTGGCTATAAT
TTTAATATAAATCATATTTTTCAAATTCTAGAATGGCTAATTCATGAGGTTGATTTACCCTTACATTATCCTTTGGTTTT
AGGGAATCCCCGGCCAATTGAATTATTAATCTTATTTTTCCTAATCGGTTTGTTAATTGATAATCTCTTTAAGAAAAGAA
GACAAATAATTTTTGCTGGCCTAATTGTTTGTAGTTTTTTTATTTGTAAAAATCCAGTTTACCCCAGTATCACAGCAGTT
GATATTGGCCAAGGGGATAGTATTTTTTTGCAAGATAAATTTAATAAAAAAACAATTTTGATTGATACAGGCGGACGATT
AGCCCTTCCGCAAGAAAGTTGGCAAAAACCTCAAAGTCAAACAAATGCCGAAAAAACACTCATTCCATATCTTGAATCTG
TTGGAGTAAGTCAGATCGACCAGCTCATTTTGACGCATACGGACGCTGACCATGTTGGAGATTTTTTGAATTTAGCTGAT
AAAATAAAAATAAAAGAAATTTGGGTTAGCCCCGGTGAATTGACAAATAATCATTTTGTAGAAAAATTGAAGAAAGCAAA
TATTGCGATTCACATCAGTAAAGTTGGAGATGAAATTCCAATCTTTGATAGTGCTTTACAAGTTTTATCAAATGGTTATA
CAGGAAAAGGGGATAATAATGATTCTATCGTGACTTATGGAAATTTTTATCATACAAAATTTCTATTTACAGGGGATTTA
GAACAAGAAGGAGAAAAAGAACTGCTCAAGAATTATCCTAAATTAAAAGTTGATGTCTTAAAAGTAGGTCATCATGGCAG
TAAAACAAGTTCAAACCCTGACTTTATTAAAGAAATTAACCCCAAACTTGCCCTCATTTCGGTTGGCAAGGAAAATCGAT
ATGGACATCCCAACCAAGAAACTCTAGAAACTTTTAAAAAATACCAAATCAGAATACTTAGAACCGATCAAAAGGGAGCG
CTTAAATTAATGCAAATCAATCAACAGTGGCGAATCCAAACAGTTAGATAA

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (27-171)

• Metallo-beta-lactamase superfamily (Lactamase_B) (483-689)

• Competence protein (Competence) (206-446)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Lactococcus lactis subsp. cremoris KW2	77.038	100	0.77
comEC/celB	Streptococcus mitis SK321	44.609	100	0.45
comEC/celB	Streptococcus mitis NCTC 12261	44.474	100	0.448
comEC/celB	Streptococcus pneumoniae TIGR4	43.742	100	0.442
comEC/celB	Streptococcus pneumoniae Rx1	43.338	100	0.438
comEC/celB	Streptococcus pneumoniae D39	43.338	100	0.438
comEC/celB	Streptococcus pneumoniae R6	43.338	100	0.438