Detailed information NTG0358870

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: E8M06_RS11140
• Genome accession: NZ_CP039462
• Coordinates: 2281063..2282259 (+)
• Length: 398 a.a.
• NCBI ID: WP_136581680.1
• Uniprot ID: -
• Organism: Streptococcus suis strain WUSS351
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2276063..2287259

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E8M06_RS11095 (E8M06_11105)	-	2276756..2277397 (+)	642	WP_044687191.1	replication protein	-
E8M06_RS11100 (E8M06_11110)	-	2277403..2277687 (+)	285	WP_015647601.1	hypothetical protein	-
E8M06_RS11105 (E8M06_11115)	-	2277680..2278012 (+)	333	WP_044676808.1	DUF771 domain-containing protein	-
E8M06_RS11110 (E8M06_11120)	-	2278075..2279196 (+)	1122	WP_044687193.1	site-specific integrase	-
E8M06_RS11130 (E8M06_11140)	-	2279702..2280385 (-)	684	WP_053867304.1	YoaK family protein	-
E8M06_RS11135 (E8M06_11145)	rlmH	2280410..2280889 (-)	480	WP_004194528.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
E8M06_RS11140 (E8M06_11150)	htrA	2281063..2282259 (+)	1197	WP_136581680.1	trypsin-like peptidase domain-containing protein	Regulator
E8M06_RS11145 (E8M06_11155)	spo0J	2282320..2283084 (+)	765	WP_099833035.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 398 a.a.
• Molecular weight: 41880.91 Da
• Isoelectric Point: 4.4971

>NTDB_id=358870 E8M06_RS11140 WP_136581680.1 2281063..2282259(+) (htrA) [Streptococcus suis strain WUSS351]
MERIPYMKKYLKFAILFVIGFFGGLIGALSASFFQPQVQQANSAITSVSNVQYNNETSTTKAVEKVQNAVVSVINYQKSA
NNSLGAIFGNIESSDELAVAGEGSGVIYKKDGQYAYIVTNTHVINNAEKIDILLASGEKISGELVGSDTYSDIAVIKISA
DKVTTVAEFADSDTIKVGETAIAIGSPLGSVYANTVTQGIISSLSRTVTSQSEDGQTISTNAIQTDTAINPGNSGGPLIN
IQGQVIGITSSKITSSSVSSSGVAVEGMGFAIPANDAVAIINQLEKDGKVSRPALGVHMVNLTTLSTSQLEKAGLSNTEL
TSGVVIVSTQSGLPADGKLETFDVITEIDGEAIQNKSDLQSALYKHQIGDTITITYYRNNQKQTVDIKLTHSTEELSE

Nucleotide

• Length: 1197 bp

>NTDB_id=358870 E8M06_RS11140 WP_136581680.1 2281063..2282259(+) (htrA) [Streptococcus suis strain WUSS351]
ATGGAAAGGATTCCTTATATGAAAAAATATTTGAAATTTGCGATTCTATTTGTAATTGGATTTTTTGGGGGTCTTATCGG
GGCCTTATCAGCCTCTTTCTTCCAACCACAGGTTCAACAAGCAAATTCTGCTATCACTAGTGTCAGCAATGTTCAATATA
ATAATGAAACTTCCACCACAAAAGCTGTAGAGAAAGTACAAAATGCTGTTGTGTCTGTTATTAATTACCAAAAGTCAGCC
AACAATAGTCTTGGTGCTATCTTTGGAAATATTGAATCATCTGACGAACTAGCTGTTGCTGGAGAGGGGTCTGGGGTTAT
CTATAAAAAAGATGGTCAATATGCCTATATTGTGACAAATACACATGTTATTAATAACGCAGAAAAAATTGATATTCTTT
TAGCATCTGGAGAAAAAATCAGCGGTGAACTCGTTGGTTCCGATACCTATTCTGATATAGCTGTTATAAAAATATCAGCA
GATAAAGTCACTACTGTTGCTGAATTTGCTGATTCCGATACAATTAAAGTTGGAGAAACTGCTATCGCAATTGGTAGTCC
TCTAGGTAGTGTCTACGCCAATACAGTTACTCAAGGTATTATTTCCAGCCTAAGTCGGACAGTTACTTCACAATCAGAAG
ACGGACAAACAATCTCAACCAATGCTATTCAAACCGATACAGCTATCAACCCAGGAAACTCTGGAGGACCATTGATTAAT
ATACAAGGACAAGTTATTGGTATCACCTCTAGCAAAATCACCTCAAGTTCTGTAAGTAGCTCAGGTGTGGCTGTGGAAGG
GATGGGATTTGCTATTCCTGCAAATGATGCCGTAGCTATTATCAATCAACTTGAAAAAGATGGAAAAGTTAGCCGACCTG
CTCTTGGAGTTCATATGGTTAACTTGACGACCTTGTCAACTAGTCAATTGGAAAAAGCTGGATTATCAAATACGGAATTA
ACATCTGGTGTAGTAATTGTCTCTACACAAAGTGGGCTACCTGCAGATGGAAAATTAGAAACTTTTGATGTTATTACTGA
GATTGACGGAGAAGCTATTCAAAATAAGAGTGATCTACAGAGCGCTCTCTACAAACATCAAATTGGAGATACAATCACTA
TAACTTATTACCGCAACAATCAGAAACAAACTGTTGACATTAAGTTGACACATTCTACAGAAGAACTTAGCGAATAA

Domains

Predicted by InterproScan.

• Trypsin-like peptidase domain (Trypsin_2) (103-248)

• PDZ domain (PDZ_2) (293-389)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	60.705	99.749	0.606
htrA	Streptococcus gordonii str. Challis substr. CH1	60.253	99.246	0.598
htrA	Streptococcus pneumoniae D39	58.015	98.744	0.573
htrA	Streptococcus pneumoniae TIGR4	58.015	98.744	0.573
htrA	Streptococcus mitis NCTC 12261	58.015	98.744	0.573
htrA	Streptococcus pneumoniae R6	58.015	98.744	0.573
htrA	Streptococcus pneumoniae Rx1	58.015	98.744	0.573