Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   E8M06_RS00360 Genome accession   NZ_CP039462
Coordinates   61100..62002 (+) Length   300 a.a.
NCBI ID   WP_044668627.1    Uniprot ID   A0A0Z8H8G0
Organism   Streptococcus suis strain WUSS351     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IS/Tn 59401..60888 61100..62002 flank 212


Gene organization within MGE regions


Location: 59401..62002
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E8M06_RS00360 (E8M06_00360) comR 61100..62002 (+) 903 WP_044668627.1 helix-turn-helix domain-containing protein Regulator

Sequence

Protein


Download         Length: 300 a.a.        Molecular weight: 35438.56 Da        Isoelectric Point: 4.4032

>NTDB_id=358821 E8M06_RS00360 WP_044668627.1 61100..62002(+) (comR) [Streptococcus suis strain WUSS351]
MNDKEFGQRVRQLRESANMTREQFCDDELELSVRQLTRIEAGTSKPTFSKIQYIATRLGMGLYELMPDYVSLPERYSKLK
FDVLRTPTYENEELMEKRADMMTEIYDEYYDDLPEEEKIAIDAIQSIIDVFETKTAEFGQDILEDYFEQIHRKKQFSVND
LLIIQLYLINLRMEVKQSSDFQYFLELVEKFPSQVELVESGDLFILRDVMITSVGLLGQKEEFSYIPTLFEALDKIMQKT
QDFQKKPILNLLKWKYELLINKDKDAATALYEEALLFARIIGNAHLTAKLEEEWRKDSQL

Nucleotide


Download         Length: 903 bp        

>NTDB_id=358821 E8M06_RS00360 WP_044668627.1 61100..62002(+) (comR) [Streptococcus suis strain WUSS351]
ATGAACGATAAGGAATTTGGACAACGTGTGCGCCAGCTGCGAGAATCAGCCAATATGACGCGTGAACAGTTTTGTGATGA
TGAACTGGAGCTCTCCGTCCGCCAATTAACCCGTATCGAAGCAGGTACTTCTAAGCCGACTTTTTCAAAAATCCAATATA
TCGCAACCCGCTTAGGCATGGGGCTCTATGAGCTTATGCCAGATTATGTGTCTCTGCCTGAACGATATTCCAAACTGAAG
TTTGATGTACTCCGTACACCGACTTATGAAAATGAGGAATTGATGGAAAAACGGGCAGATATGATGACAGAAATTTATGA
TGAATATTATGATGACTTGCCTGAAGAAGAGAAAATAGCGATTGATGCCATTCAATCTATTATTGATGTATTTGAAACGA
AGACAGCAGAATTTGGTCAAGATATTCTAGAAGATTATTTTGAACAGATACATAGAAAAAAACAATTTTCAGTCAATGAT
TTGTTGATAATCCAGCTCTATTTAATCAATTTGAGAATGGAAGTTAAACAGAGTAGTGATTTCCAGTATTTTTTAGAGTT
GGTTGAAAAGTTTCCGAGTCAAGTAGAATTAGTTGAATCTGGGGATTTGTTTATTTTAAGGGATGTGATGATAACTTCTG
TTGGACTTTTGGGACAAAAGGAAGAATTTAGCTATATTCCTACACTCTTTGAAGCACTTGATAAGATAATGCAGAAGACC
CAAGATTTTCAAAAGAAACCTATTCTTAATCTGCTTAAGTGGAAATATGAGTTGTTAATAAATAAAGATAAAGATGCAGC
AACTGCCTTATATGAAGAAGCACTTCTTTTTGCAAGAATAATTGGTAATGCACACCTAACGGCTAAATTAGAAGAAGAGT
GGAGAAAAGATAGTCAATTATAG

Domains

Predicted by InterproScan.

Helix-turn-helix domain (HTH_31)

(5-60)

ComR tetratricopeptide (ComR_TPR)

(73-294)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0Z8H8G0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus suis P1/7

67.224

99.667

0.67
  comR Streptococcus suis 05ZYH33

67.224

99.667

0.67
  comR Streptococcus suis D9

60.797

100

0.61
  comR Streptococcus mutans UA159

43.144

99.667

0.43
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

40.345

96.667

0.39
  comR Streptococcus pyogenes MGAS8232

39.527

98.667

0.39

Multiple sequence alignment