Detailed information NTG0358816

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: E8M05_RS11185
• Genome accession: NZ_CP039457
• Coordinates: 2147537..2148802 (+)
• Length: 421 a.a.
• NCBI ID: WP_013852370.1
• Uniprot ID: A0AAE6YQ67
• Organism: Streptococcus pasteurianus strain WUSP067
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2142537..2153802

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E8M05_RS11155 (E8M05_11145)	-	2143004..2145598 (+)	2595	WP_136596478.1	YfhO family protein	-
E8M05_RS11170 (E8M05_11160)	-	2146155..2146298 (+)	144	WP_160312943.1	hypothetical protein	-
E8M05_RS11180 (E8M05_11170)	rlmH	2146847..2147326 (-)	480	WP_003067023.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
E8M05_RS11185 (E8M05_11175)	htrA	2147537..2148802 (+)	1266	WP_013852370.1	S1C family serine protease	Regulator
E8M05_RS11190 (E8M05_11180)	spo0J	2148862..2149638 (+)	777	WP_003067028.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 421 a.a.
• Molecular weight: 43814.70 Da
• Isoelectric Point: 4.1803

>NTDB_id=358816 E8M05_RS11185 WP_013852370.1 2147537..2148802(+) (htrA) [Streptococcus pasteurianus strain WUSP067]
MKKIKLPKLPKLPKFNYKNWLKPLGVILVGFIAGIAGTILVLNMAGISITNVSGSSTKTTTSSVSYSNSNDTTKAVEKVQ
DAVVSVINYKSDSSSSASDLYNQMFGNDSDSSSNSSSTDDLTVYSEGSGVIYKKDGDSAYVVTNNHVIDGAEQIEIMLAN
GTKVVGELVGADTYSDIAVVKISSDNVSTVAEFADSDKLTVGETAIAIGSPLGTEYANSVTQGIVSSLSRTVTMTNDDGE
TISTNAIQTDAAINPGNSGGALINIEGQVIGINSSKISSTSSSGESVEGMGFAIPSNDVVSIINQLEENGQVIRPALGIS
MINLSDLSTNAIAQLNIPTSVTSGVVVAAVQSGMPAEGNLEQYDVITAIDDKEVTSTSDLQSILYTHSVGDSVKVTFYRG
TDKKTATIELTKTTQDLSSSN

Nucleotide

• Length: 1266 bp

>NTDB_id=358816 E8M05_RS11185 WP_013852370.1 2147537..2148802(+) (htrA) [Streptococcus pasteurianus strain WUSP067]
GTGAAAAAAATAAAATTACCAAAATTACCCAAGTTACCAAAATTTAATTACAAAAATTGGTTAAAACCATTGGGTGTCAT
TTTAGTCGGCTTTATAGCTGGTATCGCAGGTACAATACTCGTCCTAAACATGGCAGGTATTTCAATCACTAACGTCAGTG
GTTCAAGTACAAAAACAACAACAAGTAGCGTAAGCTATTCTAACTCTAACGATACAACAAAAGCTGTGGAAAAAGTTCAA
GACGCGGTTGTATCTGTTATTAACTACAAATCAGACTCGTCATCTTCTGCAAGTGACCTCTACAATCAAATGTTTGGCAA
TGACTCAGACAGTAGTAGCAATTCAAGCTCTACAGATGATTTGACTGTTTACAGTGAGGGGTCTGGGGTTATTTACAAAA
AAGATGGTGATTCTGCCTATGTCGTCACTAACAATCACGTTATTGATGGTGCCGAACAAATTGAAATTATGCTTGCTAAT
GGAACAAAAGTTGTTGGTGAGCTAGTCGGAGCAGATACTTATTCAGATATTGCTGTTGTTAAAATTTCTTCTGACAATGT
ATCTACAGTTGCTGAATTTGCCGATTCTGATAAATTGACTGTCGGTGAAACTGCTATCGCTATTGGTAGCCCACTTGGTA
CTGAATATGCTAACTCTGTAACACAAGGTATTGTCTCAAGTCTTAGCCGTACAGTAACCATGACAAATGATGATGGTGAA
ACTATCTCAACAAATGCTATCCAAACAGATGCAGCAATTAACCCAGGTAACTCTGGTGGTGCTTTAATTAACATTGAAGG
ACAAGTTATCGGTATCAATTCAAGTAAGATTTCATCTACATCAAGTTCTGGTGAATCTGTCGAAGGTATGGGATTTGCCA
TTCCATCTAACGATGTTGTATCCATTATTAACCAATTGGAAGAAAATGGGCAAGTTATCCGCCCAGCACTTGGTATTTCA
ATGATAAACTTGAGCGACCTTTCAACTAATGCAATTGCTCAACTTAACATTCCAACAAGTGTAACAAGCGGTGTCGTTGT
TGCCGCTGTTCAATCTGGTATGCCTGCTGAAGGTAATCTCGAACAGTACGATGTCATCACAGCTATTGACGACAAAGAAG
TAACATCTACTTCAGATCTTCAAAGTATTCTTTATACTCATTCTGTTGGTGACTCTGTCAAAGTAACCTTCTACCGTGGA
ACTGATAAGAAAACAGCTACAATTGAATTAACTAAGACAACGCAAGATTTATCTTCCTCAAACTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (315-410)

• Trypsin-like peptidase domain (Trypsin_2) (127-272)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	64.938	96.2	0.625
htrA	Streptococcus gordonii str. Challis substr. CH1	59.804	96.912	0.58
htrA	Streptococcus pneumoniae D39	57.664	97.625	0.563
htrA	Streptococcus pneumoniae TIGR4	57.664	97.625	0.563
htrA	Streptococcus mitis NCTC 12261	57.664	97.625	0.563
htrA	Streptococcus pneumoniae R6	57.664	97.625	0.563
htrA	Streptococcus pneumoniae Rx1	57.664	97.625	0.563