Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   D11S_RS09945 Genome accession   NC_013416
Coordinates   1992046..1993269 (+) Length   407 a.a.
NCBI ID   WP_012821128.1    Uniprot ID   -
Organism   Aggregatibacter actinomycetemcomitans D11S-1     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1987046..1998269
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D11S_RS09925 (D11S_2067) nanQ 1988545..1989015 (+) 471 WP_005547536.1 N-acetylneuraminate anomerase -
  D11S_RS09930 (D11S_2069) ampD 1989489..1990043 (-) 555 WP_005567973.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  D11S_RS09935 (D11S_2070) pilA 1990165..1990617 (+) 453 WP_005586498.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  D11S_RS09940 (D11S_2071) pilB 1990644..1992053 (+) 1410 WP_012821127.1 GspE/PulE family protein Machinery gene
  D11S_RS09945 (D11S_2072) pilC 1992046..1993269 (+) 1224 WP_012821128.1 type II secretion system F family protein Machinery gene
  D11S_RS09950 (D11S_2073) - 1993266..1993955 (+) 690 WP_005547547.1 prepilin peptidase -
  D11S_RS09955 (D11S_2074) coaE 1994005..1994628 (+) 624 WP_005547548.1 dephospho-CoA kinase -
  D11S_RS09960 (D11S_2075) yacG 1994618..1994830 (+) 213 WP_005547550.1 DNA gyrase inhibitor YacG -
  D11S_RS09965 (D11S_2076) - 1994830..1995102 (+) 273 WP_005547552.1 GNAT family N-acetyltransferase -
  D11S_RS09970 (D11S_2077) - 1995499..1996872 (+) 1374 WP_012821129.1 alanine/glycine:cation symporter family protein -
  D11S_RS09980 (D11S_2078) raiA 1997101..1997424 (+) 324 WP_005540708.1 ribosome-associated translation inhibitor RaiA -
  D11S_RS09985 (D11S_2079) - 1997573..1998127 (+) 555 WP_005547559.1 DUF5358 domain-containing protein -

Sequence

Protein


Download         Length: 407 a.a.        Molecular weight: 46090.56 Da        Isoelectric Point: 9.9659

>NTDB_id=35490 D11S_RS09945 WP_012821128.1 1992046..1993269(+) (pilC) [Aggregatibacter actinomycetemcomitans D11S-1]
MIKLKLFQWRAVNRLQQKQKDLIVAETEAMAQQQLLSCGLQNIKLQQNWQFSHKPKNADICTLLSQLATLLQAAVPLKNS
LQILLQNCTNIALNRWLRCLLQEIESGLAFSQALEQQGLYLTYQERQLIQVGEMTGKLAAVCHEIAQHKQQALALQRKIQ
KILLYPLLVLGISLILTALLLLFIVPQFAAMYDNSNAQLPVFTQVLLALSQGLQGYWFALLMFIALTVALIRFRLKHSPW
LNRQKNRLINSIPLLNRIVQLSRLVGFSHSLFLMLQAGIPLNQALQSFLPKQQSWQTKPQQQGDWLLIEGVQSALHWIQQ
GYPFSASVSGQIFPPAAQQMLQVGEQSGQLPKMLQFIANDHQQQLDHQIDLLSQMLEPLLMVIIGGLIGLIMLGMYLPIF
NMGSLVQ

Nucleotide


Download         Length: 1224 bp        

>NTDB_id=35490 D11S_RS09945 WP_012821128.1 1992046..1993269(+) (pilC) [Aggregatibacter actinomycetemcomitans D11S-1]
ATGATTAAATTGAAACTGTTTCAATGGCGCGCCGTTAATCGACTACAGCAAAAACAAAAAGACTTAATCGTGGCGGAAAC
GGAGGCGATGGCACAACAACAGCTGCTTTCATGCGGGTTGCAAAACATCAAATTACAACAAAACTGGCAATTTAGCCACA
AACCGAAAAATGCCGACATCTGCACGCTGCTTTCCCAACTGGCGACGCTGTTACAAGCCGCCGTGCCGCTGAAAAACAGC
CTGCAAATTTTATTGCAAAATTGTACCAATATTGCGTTGAATCGCTGGCTACGCTGCTTGCTACAGGAGATTGAAAGCGG
CTTAGCATTTTCTCAAGCATTGGAACAACAAGGTTTATACTTAACCTATCAGGAACGCCAACTGATTCAGGTGGGTGAAA
TGACAGGCAAACTTGCCGCCGTTTGTCATGAAATCGCACAACATAAACAACAGGCGCTGGCGTTGCAGCGTAAAATTCAG
AAAATCCTGCTTTATCCGTTGCTGGTGCTCGGAATCTCATTGATTTTGACCGCACTTTTATTGCTGTTCATCGTGCCGCA
ATTTGCCGCCATGTATGACAACAGCAACGCGCAACTGCCCGTGTTCACGCAGGTTTTACTAGCCCTTTCCCAAGGCTTGC
AGGGTTATTGGTTCGCGCTGCTCATGTTTATTGCGCTGACCGTGGCGTTAATTCGCTTTCGCCTCAAACATTCGCCTTGG
CTTAACCGACAAAAAAACCGGCTGATTAACAGTATTCCGCTACTTAATCGTATCGTACAACTCTCCCGTTTAGTGGGATT
CAGTCACAGCTTGTTTTTGATGTTACAGGCAGGTATTCCGCTGAATCAGGCGCTACAATCTTTCCTACCGAAACAACAAA
GCTGGCAAACTAAACCGCAGCAGCAAGGGGATTGGCTGCTTATTGAGGGAGTGCAATCGGCACTGCATTGGATTCAACAA
GGCTATCCGTTCTCCGCCAGCGTAAGCGGACAAATCTTCCCGCCGGCGGCACAACAAATGCTGCAAGTCGGCGAACAAAG
CGGTCAATTGCCGAAAATGCTGCAATTTATCGCCAACGATCATCAGCAACAATTGGATCACCAAATCGATCTACTGTCAC
AAATGCTGGAACCGTTGTTGATGGTAATTATCGGCGGGCTGATCGGCTTGATTATGCTCGGTATGTATTTACCGATTTTC
AACATGGGCTCGCTGGTACAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(64-186)

Type II secretion system (T2SS), protein F (T2SSF)

(267-398)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae Rd KW20

63.027

99.017

0.624
  pilC Haemophilus influenzae 86-028NP

62.283

99.017

0.617
  pilC Glaesserella parasuis strain SC1401

39.152

98.526

0.386

Multiple sequence alignment