Detailed information    

insolico Bioinformatically predicted

Overview

Name   comM   Type   Machinery gene
Locus tag   D11S_RS00650 Genome accession   NC_013416
Coordinates   124032..124736 (+) Length   234 a.a.
NCBI ID   WP_005575487.1    Uniprot ID   -
Organism   Aggregatibacter actinomycetemcomitans D11S-1     
Function   require for natural transformation (predicted from homology)   
Unclear

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 121322..143287 124032..124736 within 0


Gene organization within MGE regions


Location: 121322..143287
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D11S_RS00640 (D11S_0136) - 121322..123241 (-) 1920 WP_005548209.1 Mu transposase C-terminal domain-containing protein -
  D11S_RS00645 (D11S_0137) - 123234..123896 (-) 663 WP_005548207.1 heteromeric transposase endonuclease subunit TnsA -
  D11S_RS00650 comM 124032..124736 (+) 705 WP_005575487.1 ATP-binding protein Machinery gene
  D11S_RS00655 (D11S_0139) - 124748..125566 (-) 819 WP_005548203.1 divergent polysaccharide deacetylase family protein -
  D11S_RS00660 (D11S_0140) envC 125572..126831 (-) 1260 WP_032999579.1 murein hydrolase activator EnvC -
  D11S_RS00665 (D11S_0141) - 127040..128698 (-) 1659 WP_012820810.1 phospho-sugar mutase -
  D11S_RS00670 (D11S_0142) - 129004..129687 (+) 684 WP_005548197.1 2,3-diphosphoglycerate-dependent phosphoglycerate mutase -
  D11S_RS00675 (D11S_0143) - 129772..130266 (-) 495 WP_005548195.1 YfbU family protein -
  D11S_RS00680 (D11S_0144) - 130284..131027 (-) 744 WP_032996149.1 VacJ family lipoprotein -
  D11S_RS00685 (D11S_0145) nikA 131126..132709 (-) 1584 WP_005548193.1 nickel ABC transporter substrate-binding protein -
  D11S_RS00690 (D11S_0146) hslU 132775..134106 (-) 1332 WP_005538655.1 HslU--HslV peptidase ATPase subunit -
  D11S_RS00695 (D11S_0147) hslV 134127..134654 (-) 528 WP_005548189.1 ATP-dependent protease subunit HslV -
  D11S_RS00700 (D11S_0149) aphA 134869..135576 (+) 708 WP_012820812.1 acid phosphatase AphA -
  D11S_RS00710 (D11S_02245) - 135958..136275 (-) 318 Protein_135 DUF4298 domain-containing protein -
  D11S_RS00720 (D11S_0152) mtr 136554..137798 (-) 1245 WP_005548180.1 tryptophan permease -
  D11S_RS00725 (D11S_0153) ppa 137960..138487 (+) 528 WP_005548178.1 inorganic diphosphatase -
  D11S_RS00730 (D11S_0154) - 138563..139336 (+) 774 WP_005548176.1 M48 family metallopeptidase -
  D11S_RS00735 (D11S_0155) ribB 140016..140660 (+) 645 WP_005548174.1 3,4-dihydroxy-2-butanone-4-phosphate synthase -
  D11S_RS00740 (D11S_0156) trpS 140747..141751 (-) 1005 WP_005548172.1 tryptophan--tRNA ligase -
  D11S_RS00745 (D11S_0157) ftsY 141926..143287 (-) 1362 WP_005548170.1 signal recognition particle-docking protein FtsY -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 26184.03 Da        Isoelectric Point: 9.8867

>NTDB_id=35468 D11S_RS00650 WP_005575487.1 124032..124736(+) (comM) [Aggregatibacter actinomycetemcomitans D11S-1]
MPLICNFDSGTIPKPGEISLAHNGVLFLDELPEFERKVLDALRQPLESGEIIISRANAKIQFPAKFQLIAAMNPSPTGHY
QGTHNRTSPQQVMRYLNRLSGPFLDRFDLSIEVPLLPQGSLQNSGDRGESSATVREKVLKTRAIQLQRAGKINAHLNSKE
IERDCKLTDKDAQFLENALTKLGLSVRAYHRILKVSRTIADLDGEQHINQRHLAEALGYRAMDRLLQKLAKNSA

Nucleotide


Download         Length: 705 bp        

>NTDB_id=35468 D11S_RS00650 WP_005575487.1 124032..124736(+) (comM) [Aggregatibacter actinomycetemcomitans D11S-1]
ATGCCACTTATTTGTAACTTTGACAGCGGCACGATCCCCAAACCGGGCGAAATTTCCCTCGCTCACAATGGCGTGCTTTT
CTTAGATGAGTTGCCCGAATTTGAACGCAAAGTGCTGGACGCGCTGCGTCAACCATTGGAAAGTGGCGAAATTATTATTT
CCCGCGCCAACGCCAAGATTCAATTTCCGGCAAAATTTCAACTGATTGCCGCGATGAATCCCAGCCCGACAGGGCATTAT
CAAGGCACGCATAATCGCACCTCACCACAACAAGTTATGCGTTATCTGAATCGGTTATCCGGCCCTTTTTTAGATCGCTT
CGATTTATCCATTGAAGTGCCCTTATTACCACAAGGCAGCTTACAAAATAGCGGCGATCGTGGCGAATCCAGCGCAACGG
TGCGAGAAAAAGTCCTGAAAACCCGTGCCATTCAACTTCAGCGCGCCGGCAAAATTAATGCCCATTTAAATAGCAAAGAA
ATCGAACGGGACTGCAAACTAACCGACAAAGACGCACAGTTCCTGGAAAATGCCCTGACTAAACTGGGGCTTTCCGTACG
AGCGTACCACCGCATACTGAAAGTGTCCCGCACCATTGCCGATTTAGATGGAGAACAACACATCAACCAGCGCCATCTGG
CCGAAGCTCTGGGTTATCGGGCAATGGACAGGTTGTTGCAAAAATTGGCGAAAAACTCGGCGTAA

Domains

Predicted by InterproScan.

Magnesium chelatase, subunit ChlI (Mg_chelatase)

(9-118)

Magnesium chelatase, subunit ChlI C-terminal (Mg_chelatase_C)

(128-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comM Haemophilus influenzae Rd KW20

86.957

98.291

0.855
  comM Glaesserella parasuis strain SC1401

81.034

99.145

0.803
  comM Vibrio cholerae strain A1552

67.873

94.444

0.641
  comM Vibrio campbellii strain DS40M4

65.909

94.017

0.62
  RA0C_RS07335 Riemerella anatipestifer ATCC 11845 = DSM 15868

52

96.154

0.5
  comM Legionella pneumophila str. Paris

51.869

91.453

0.474
  comM Legionella pneumophila strain ERS1305867

51.869

91.453

0.474

Multiple sequence alignment