Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   GOM47_RS07345 Genome accession   NZ_CP046524
Coordinates   1441672..1443519 (-) Length   615 a.a.
NCBI ID   WP_235080367.1    Uniprot ID   -
Organism   Streptococcus oralis strain SOT     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1436672..1448519
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GOM47_RS07315 (GOM47_07310) - 1436841..1437332 (-) 492 WP_235080361.1 prolyl-tRNA synthetase associated domain-containing protein -
  GOM47_RS07320 (GOM47_07315) - 1437345..1437929 (-) 585 WP_235080362.1 uracil-DNA glycosylase family protein -
  GOM47_RS07325 (GOM47_07320) pepV 1437983..1439383 (-) 1401 WP_235080363.1 dipeptidase PepV -
  GOM47_RS07330 (GOM47_07325) - 1439396..1440001 (-) 606 WP_235080364.1 nitroreductase family protein -
  GOM47_RS07335 (GOM47_07330) - 1440187..1440708 (-) 522 WP_235080365.1 hypothetical protein -
  GOM47_RS07340 (GOM47_07335) - 1440843..1441682 (-) 840 WP_235080366.1 metallophosphoesterase family protein -
  GOM47_RS07345 (GOM47_07340) uvrC 1441672..1443519 (-) 1848 WP_235080367.1 excinuclease ABC subunit UvrC Machinery gene
  GOM47_RS07350 (GOM47_07345) - 1443621..1444322 (-) 702 WP_235080368.1 M57 family metalloprotease -
  GOM47_RS07355 (GOM47_07350) - 1444429..1445208 (-) 780 WP_235080369.1 alpha/beta hydrolase -
  GOM47_RS07360 (GOM47_07355) - 1445277..1446938 (-) 1662 WP_235080370.1 ribonuclease J -

Sequence

Protein


Download         Length: 615 a.a.        Molecular weight: 70608.16 Da        Isoelectric Point: 9.1021

>NTDB_id=352831 GOM47_RS07345 WP_235080367.1 1441672..1443519(-) (uvrC) [Streptococcus oralis strain SOT]
MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSYFRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEIN
LIKENKPKYNIMLKDDKSYPFIKITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
YYHIGQCMAHTICKKDEAYFKSMAQEVSDFLKGQDDKIIDDLKGKMAKAAQSMEFERAAEYRDLIQAIGTLRTKQRVMAK
DLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNLFPYYNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKAL
VDTKILKPQRGEKKQLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGTSPVSAMVV
FVNGKPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREGLTPPDLIVIDGGQGQVNIAKQVIQEELGLDIPIAGLQ
KNDKHQTHELLFGDPLEVVELSRNSQEFFLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMKHFKSL
TKIKEASVDEIVEVGVPRAVAEDVKRKLNPQGEVELAQVAEERVDYQTEGNHHEP

Nucleotide


Download         Length: 1848 bp        

>NTDB_id=352831 GOM47_RS07345 WP_235080367.1 1441672..1443519(-) (uvrC) [Streptococcus oralis strain SOT]
ATGAATAACTTGATCAAATCAAAACTGGAGCTCTTGCCGACCAGCCCCGGTTGTTACATTCACAAGGATAAAAATGGCAC
CATTATTTATGTCGGAAAGGCCAAAAATCTGCGCAACCGCGTACGATCCTATTTTCGTGGGAGTCACGATACCAAGACGG
AAGCTCTGGTATCTGAGATTGTGGATTTTGAATTTATCGTCACTGAGTCTAATATTGAAGCCCTTCTGCTGGAAATTAAC
CTTATCAAGGAAAACAAGCCCAAGTACAATATCATGCTCAAGGATGATAAGTCCTATCCTTTTATCAAAATCACCAATGA
GCGTTATCCTCGCTTGATCATCACCCGTCAGGTAAAAAAGGACGGTGGTCTCTACTTTGGCCCCTACCCAGATGTGGGAG
CAGCTAATGAAATCAAGCGGCTTCTAGATCGGATTTTCCCTTTTCGTAAGTGTACCAACCCGCCCTCTAAAGTCTGTTTT
TACTACCATATCGGCCAGTGTATGGCCCATACTATCTGTAAGAAGGATGAGGCTTATTTCAAGTCTATGGCTCAGGAGGT
TTCTGATTTCCTAAAAGGACAGGATGACAAAATCATCGATGACCTCAAGGGGAAGATGGCAAAGGCAGCTCAAAGTATGG
AGTTTGAACGTGCGGCGGAATACCGTGACCTGATTCAGGCCATTGGAACGCTTCGGACCAAGCAACGGGTTATGGCTAAG
GATCTTCAAAATCGCGATGTCTTTGGCTACTATGTGGACAAGGGTTGGATGTGTGTCCAGGTTTTCTTTGTTCGTCAGGG
AAAACTCATCGAGCGGGATGTCAATCTCTTCCCTTACTACAATGATCCGGATGAGGACTTCTTGACCTATGTGGGGCAAT
TTTATCAAGAAAAATCCCACCTGGTTCCCAATGAAGTGCTGATTCCGCAGGATATCGATGAAGAAGCAGTCAAGGCCTTG
GTGGATACCAAGATTCTCAAACCCCAGCGTGGAGAGAAAAAACAACTGGTCAATCTAGCCATAAAAAATGCTCGTGTTAG
TCTGGAGCAGAAGTTCAATCTGCTAGAAAAATCTGTTGAAAAGACCCAAGGAGCTATTGAAAATCTGGGACGCTTGCTCC
AAATCCCGACCCCAGTACGTATCGAGTCCTTTGATAACTCTAATATAATGGGAACTAGCCCTGTTTCAGCTATGGTAGTC
TTTGTCAATGGCAAACCGAGTAAGAAGGACTACCGAAAGTACAAGATAAAAACGGTTGTGGGTCCAGACGATTATGCTAG
TATGCGTGAGGTTATCCGCAGACGTTATGGACGAGTTCAGCGTGAGGGTTTAACCCCGCCAGATTTGATCGTCATCGATG
GGGGGCAAGGTCAAGTCAATATAGCTAAGCAAGTCATCCAAGAAGAGCTAGGTTTGGATATCCCAATTGCAGGTCTGCAA
AAGAATGATAAGCACCAAACCCATGAACTGCTCTTCGGAGATCCACTGGAAGTGGTGGAGTTGTCTCGTAATTCTCAGGA
ATTTTTCCTCCTCCAACGCATCCAAGATGAGGTACACCGCTTTGCTATCACTTTCCACCGCCAACTGCGCTCCAAAAATT
CTTTTTCATCTCAATTGGATGGGATTGACGGTCTGGGACCTAAACGCAAGCAGAATCTCATGAAGCATTTTAAATCTCTC
ACTAAAATCAAGGAAGCCAGTGTGGATGAAATTGTCGAAGTGGGTGTGCCAAGAGCAGTCGCAGAAGATGTGAAAAGAAA
GTTGAACCCTCAGGGAGAAGTGGAGTTGGCTCAAGTGGCGGAAGAGAGAGTAGATTACCAAACGGAAGGAAACCATCATG
AACCATAA

Domains

Predicted by InterProScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(372-523)

GIY-YIG catalytic domain (GIY-YIG)

(17-90)

UvrB/uvrC motif (UVR)

(196-228)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

97.886

100

0.979
  uvrC Streptococcus pneumoniae R6

97.561

100

0.976
  uvrC Streptococcus pneumoniae D39

97.561

100

0.976

Multiple sequence alignment