Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   ES298_RS10090 Genome accession   NZ_CP038253
Coordinates   1945983..1946285 (-) Length   100 a.a.
NCBI ID   WP_000413382.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901929     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1940983..1951285
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ES298_RS10060 (ES298_10600) rnpA 1941665..1942036 (-) 372 WP_000739246.1 ribonuclease P protein component -
  ES298_RS11215 - 1942053..1942184 (-) 132 WP_000768904.1 hypothetical protein -
  ES298_RS10065 (ES298_10605) - 1942185..1943375 (-) 1191 WP_000167765.1 acetate kinase -
  ES298_RS10070 (ES298_10610) comYH 1943426..1944379 (-) 954 WP_000345126.1 class I SAM-dependent methyltransferase Machinery gene
  ES298_RS10075 (ES298_10615) - 1944440..1945032 (-) 593 Protein_1983 class I SAM-dependent methyltransferase -
  ES298_RS10080 (ES298_10620) comGG/cglG 1945135..1945581 (-) 447 WP_001809944.1 competence type IV pilus minor pilin ComGG Machinery gene
  ES298_RS10085 (ES298_10625) comGF/cglF 1945559..1946020 (-) 462 WP_000250531.1 competence type IV pilus minor pilin ComGF Machinery gene
  ES298_RS10090 (ES298_10630) comGE/cglE 1945983..1946285 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  ES298_RS10095 (ES298_10635) comGD/cglD 1946248..1946682 (-) 435 WP_033606693.1 competence type IV pilus minor pilin ComGD Machinery gene
  ES298_RS10100 (ES298_10640) comGC/cglC 1946645..1946968 (-) 324 WP_000738628.1 comG operon protein ComGC Machinery gene
  ES298_RS10105 (ES298_10645) comGB/cglB 1946970..1947986 (-) 1017 WP_078130737.1 competence type IV pilus assembly protein ComGB Machinery gene
  ES298_RS10110 (ES298_10650) comGA/cglA/cilD 1947934..1948875 (-) 942 WP_000249536.1 competence type IV pilus ATPase ComGA Machinery gene
  ES298_RS10115 (ES298_10655) - 1948951..1949316 (-) 366 WP_000286415.1 DUF1033 family protein -
  ES298_RS10120 (ES298_10660) - 1949467..1950525 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -

Sequence

Protein


Download         Length: 100 a.a.        Molecular weight: 11108.08 Da        Isoelectric Point: 9.7273

>NTDB_id=352736 ES298_RS10090 WP_000413382.1 1945983..1946285(-) (comGE/cglE) [Streptococcus pneumoniae strain TVO_1901929]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVSINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide


Download         Length: 303 bp        

>NTDB_id=352736 ES298_RS10090 WP_000413382.1 1945983..1946285(-) (comGE/cglE) [Streptococcus pneumoniae strain TVO_1901929]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCTTGCAGACGGGGCAAAATCAGGTAAGCATCAACGGAGTTGAGATTCAGGTATTTTCT
AGTGAAAAAGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(16-97)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae Rx1

100

100

1
  comGE/cglE Streptococcus pneumoniae D39

100

100

1
  comGE/cglE Streptococcus pneumoniae R6

100

100

1
  comGE/cglE Streptococcus pneumoniae TIGR4

100

100

1
  comGE/cglE Streptococcus mitis NCTC 12261

98

100

0.98
  comGE/cglE Streptococcus mitis SK321

98

100

0.98
  comYE Streptococcus mutans UA140

44.444

90

0.4
  comYE Streptococcus mutans UA159

44.444

90

0.4

Multiple sequence alignment