Detailed information NTG0352735

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: ES298_RS10085
• Genome accession: NZ_CP038253
• Coordinates: 1945559..1946020 (-)
• Length: 153 a.a.
• NCBI ID: WP_000250531.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain TVO_1901929
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1940559..1951020

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ES298_RS10055 (ES298_10595)	-	1940866..1941690 (-)	825	WP_000727904.1	membrane protein insertase YidC	-
ES298_RS10060 (ES298_10600)	rnpA	1941665..1942036 (-)	372	WP_000739246.1	ribonuclease P protein component	-
ES298_RS11215	-	1942053..1942184 (-)	132	WP_000768904.1	hypothetical protein	-
ES298_RS10065 (ES298_10605)	-	1942185..1943375 (-)	1191	WP_000167765.1	acetate kinase	-
ES298_RS10070 (ES298_10610)	comYH	1943426..1944379 (-)	954	WP_000345126.1	class I SAM-dependent methyltransferase	Machinery gene
ES298_RS10075 (ES298_10615)	-	1944440..1945032 (-)	593	Protein_1983	class I SAM-dependent methyltransferase	-
ES298_RS10080 (ES298_10620)	comGG/cglG	1945135..1945581 (-)	447	WP_001809944.1	competence type IV pilus minor pilin ComGG	Machinery gene
ES298_RS10085 (ES298_10625)	comGF/cglF	1945559..1946020 (-)	462	WP_000250531.1	competence type IV pilus minor pilin ComGF	Machinery gene
ES298_RS10090 (ES298_10630)	comGE/cglE	1945983..1946285 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
ES298_RS10095 (ES298_10635)	comGD/cglD	1946248..1946682 (-)	435	WP_033606693.1	competence type IV pilus minor pilin ComGD	Machinery gene
ES298_RS10100 (ES298_10640)	comGC/cglC	1946645..1946968 (-)	324	WP_000738628.1	comG operon protein ComGC	Machinery gene
ES298_RS10105 (ES298_10645)	comGB/cglB	1946970..1947986 (-)	1017	WP_078130737.1	competence type IV pilus assembly protein ComGB	Machinery gene
ES298_RS10110 (ES298_10650)	comGA/cglA/cilD	1947934..1948875 (-)	942	WP_000249536.1	competence type IV pilus ATPase ComGA	Machinery gene
ES298_RS10115 (ES298_10655)	-	1948951..1949316 (-)	366	WP_000286415.1	DUF1033 family protein	-
ES298_RS10120 (ES298_10660)	-	1949467..1950525 (-)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17849.37 Da
• Isoelectric Point: 6.4832

>NTDB_id=352735 ES298_RS10085 WP_000250531.1 1945559..1946020(-) (comGF/cglF) [Streptococcus pneumoniae strain TVO_1901929]
MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQAMSQLLISEVRYQQQSEQKEWLLFVDQLEVELDRSQFEKVEGN
RLYMKQDGKDIAIGKSKSDDFRKTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES

Nucleotide

• Length: 462 bp

>NTDB_id=352735 ES298_RS10085 WP_000250531.1 1945559..1946020(-) (comGF/cglF) [Streptococcus pneumoniae strain TVO_1901929]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTGCTTGCCCTCAT
TGTCATCAGTGGGGGATTACTCCTTTTTCAAGCTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGACCAACTTGAGGTAGAATTAGACCGTTCGCAGTTCGAAAAAGTAGAAGGCAAT
CGCCTATACATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGACGATTTTCGTAAAACCGATGCTAG
TGGACGGGGGTATCAGCCTATGGTTTATGGCCTCAAATCAGCTCAGATTACAGAGGACAATCAACTGGTTCATTTTCGTT
TCCAGTTTCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAGAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	95.425	100	0.954
comGF/cglF	Streptococcus pneumoniae D39	95.425	100	0.954
comGF/cglF	Streptococcus pneumoniae R6	95.425	100	0.954
comGF/cglF	Streptococcus pneumoniae TIGR4	95.425	100	0.954
comGF/cglF	Streptococcus mitis SK321	92.81	100	0.928
comGF/cglF	Streptococcus mitis NCTC 12261	91.503	100	0.915